Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sarah O' Connell"'
Autor:
Kai Wu, Ian N. Moore, Bridget Bart, John-Paul Todd, Elham Bayat Mokhtari, Gabriela S. Alvarado, Swagata Kar, Jaclyn Wear, Manjari Sriparna, Kathryn E. Foulds, Matthew Gagne, Mario Roederer, Kizzmekia S. Corbett, Seyhan Boyoglu-Barnum, Darin K. Edwards, Barbara J. Flynn, Katelyn Steingrebe, Adrian B. McDermott, Samantha J. Provost, Angela Choi, Shayne F. Andrew, Eli Boritz, Sayda Elbashir, Zackery Flinchbaugh, Timothy S. Johnston, Martha Nason, Sarah O’ Connell, Anthony Cook, Bianca M. Nagata, Mahnaz Minai, Prakriti Mudvari, Mark G. Lewis, Andrew Pekosz, Amy R. Henry, Farida Laboune, Dillon R. Flebbe, Becky Chang, Alex Van Ry, Nancy J. Sullivan, Juan I. Moliva, Saule T. Nurmukhambetova, Laurent Pessaint, Lilin Lai, Matthew A. Koch, Barney S. Graham, Hanne Leth Andersen, Maciel Porto, Kevin W. Bock, Daniel C. Douek, Anne P. Werner, Mehul S. Suthar, Evan Lamb, Alan Dodson, Andrea Carfi, Robert A. Seder
Publikováno v:
Nature Immunology. 22:1306-1315
B.1.351 is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant most resistant to antibody neutralization. We demonstrate how the dose and number of immunizations influence protection. Nonhuman primates received two doses of 30 or
Autor:
Daniel C. Douek, Rachel L. Davis, Alex Van Ry, Timothy S. Johnston, Stephen D. Schmidt, Adrian B. McDermott, John R. Mascola, Yi Zhang, Anne P. Werner, Lilin Lai, Evan Lamb, Sarah O’ Connell, Kevin W. Bock, John-Paul Todd, Misook Choe, Amy R. Henry, Wei Shi, Alan Dodson, Danielle A. Wagner, Matthew A. Koch, Barney S. Graham, Aurélie Ploquin, Mehul S. Suthar, Farida Laboune, Chaim A. Schramm, Mitzi M. Donaldson, Samantha J. Provost, John Misasi, Christopher Stringham, Bianca M. Nagata, Hanne Leth Andersen, Ian N. Moore, Kizzmekia S. Corbett, Andrea Carfi, Robert A. Seder, Sandeep Narpala, Seyhan Boyoglu-Barnum, Mark G. Lewis, Josue Marquez, Sijy O'Dell, Nancy J. Sullivan, Lingshu Wang, Juan I. Moliva, Saule T. Nurmukhambetova, Courtney Tucker, Zackery Flinchbaugh, Laurent Pessaint, Shayne F. Andrew, Mahnaz Minai, Eli Boritz, Barbara J. Flynn, Andrew Pekosz, Dillon R. Flebbe, Daniel Valentin, Darin K. Edwards, Matthew Gagne, Angela Choi, Manjari Sriparna, Kathryn E. Foulds, Martha Nason, Anthony L. Cook, Gabriela S. Alvarado, Kai Wu, Nicole A. Doria-Rose, Mario Roederer
Publikováno v:
bioRxiv
Neutralizing antibody responses gradually wane after vaccination with mRNA-1273 against several variants of concern (VOC), and additional boost vaccinations may be required to sustain immunity and protection. Here, we evaluated the immune responses i
Autor:
Kizzmekia S. Corbett, Anne P. Werner, Sarah O’ Connell, Matthew Gagne, Lilin Lai, Juan I. Moliva, Barbara Flynn, Angela Choi, Matthew Koch, Kathryn E. Foulds, Shayne F. Andrew, Dillon R. Flebbe, Evan Lamb, Saule T. Nurmukhambetova, Samantha J. Provost, Kevin W. Bock, Mahnaz Minai, Bianca M. Nagata, Alex Van Ry, Zackery Flinchbaugh, Timothy S. Johnston, Elham Bayat Mokhtari, Prakriti Mudvari, Amy R. Henry, Farida Laboune, Becky Chang, Maciel Porto, Jaclyn Wear, Gabriela S. Alvarado, Seyhan Boyoglu-Barnum, John-Paul M. Todd, Bridget Bart, Anthony Cook, Alan Dodson, Laurent Pessaint, Katelyn Steingrebe, Sayda Elbashir, Hanne Andersen, Kai Wu, Darin K. Edwards, Swagata Kar, Mark G. Lewis, Eli Bortiz, Ian N. Moore, Andrea Carfi, Mehul S. Suthar, Adrian McDermott, Mario Roederer, Martha C. Nason, Nancy J. Sullivan, Daniel C. Douek, Barney S. Graham, Robert A. Seder
Publikováno v:
bioRxiv
BackgroundVaccine efficacy against the B.1.351 variant following mRNA-1273 vaccination in humans has not been determined. Nonhuman primates (NHP) are a useful model for demonstrating whether mRNA-1273 mediates protection against B.1.351.MethodsNonhum
Autor:
Kizzmekia S. Corbett, Martha C. Nason, Britta Flach, Matthew Gagne, Sarah O’ Connell, Timothy S. Johnston, Shruti N. Shah, Venkata Viswanadh Edara, Katharine Floyd, Lilin Lai, Charlene McDanal, Joseph R. Francica, Barbara Flynn, Kai Wu, Angela Choi, Matthew Koch, Olubukola M. Abiona, Anne P. Werner, Gabriela S. Alvarado, Shayne F. Andrew, Mitzi M. Donaldson, Jonathan Fintzi, Dillon R. Flebbe, Evan Lamb, Amy T. Noe, Saule T. Nurmukhambetova, Samantha J. Provost, Anthony Cook, Alan Dodson, Andrew Faudree, Jack Greenhouse, Swagata Kar, Laurent Pessaint, Maciel Porto, Katelyn Steingrebe, Daniel Valentin, Serge Zouantcha, Kevin W. Bock, Mahnaz Minai, Bianca M. Nagata, Juan I. Moliva, Renee van de Wetering, Seyhan Boyoglu-Barnum, Kwanyee Leung, Wei Shi, Eun Sung Yang, Yi Zhang, John-Paul M. Todd, Lingshu Wang, Hanne Andersen, Kathryn E. Foulds, Darin K. Edwards, John R. Mascola, Ian N. Moore, Mark G. Lewis, Andrea Carfi, David Montefiori, Mehul S. Suthar, Adrian McDermott, Nancy J. Sullivan, Mario Roederer, Daniel C. Douek, Barney S. Graham, Robert A. Seder
Publikováno v:
bioRxiv
Immune correlates of protection can be used as surrogate endpoints for vaccine efficacy. The nonhuman primate (NHP) model of SARS-CoV-2 infection replicates key features of human infection and may be used to define immune correlates of protection fol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a2c90ec45ef1373e88339143a1b79f
https://doi.org/10.1101/2021.04.20.440647
https://doi.org/10.1101/2021.04.20.440647