Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Sarah Naomi-James"'
Autor:
Rebecca E. Green, Jodie Lord, Marzia A. Scelsi, Jin Xu, Andrew Wong, Sarah Naomi-James, Alex Handy, Lachlan Gilchrist, Dylan M. Williams, Thomas D. Parker, Christopher A. Lane, Ian B. Malone, David M. Cash, Carole H. Sudre, William Coath, David L. Thomas, Sarah Keuss, Richard Dobson, Cristina Legido-Quigley, Nick C. Fox, Jonathan M. Schott, Marcus Richards, Petroula Proitsi, The Insight 46 study team
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background Identifying blood-based signatures of brain health and preclinical pathology may offer insights into early disease mechanisms and highlight avenues for intervention. Here, we systematically profiled associations between blood meta
Externí odkaz:
https://doaj.org/article/f5a5b80764c34bc1b3fd5049c6dcb527
Autor:
Heidi Murray-Smith, Suzie Barker, Frederik Barkhof, Josephine Barnes, Thomas M. Brown, Gabriella Captur, Molly R.E.Cartlidge, David M. Cash, William Coath, Daniel Davis, John C. Dickson, James Groves, Alun D. Hughes, Sarah-Naomi James, Ashvini Keshavan, Sarah E. Keuss, Josh King-Robson, Kirsty Lu, Ian B. Malone, Jennifer M. Nicholas, Alicja Rapala, Catherine J. Scott, Rebecca Street, Carole H. Sudre, David L. Thomas, Andrew Wong, Selina Wray, Henrik Zetterberg, Nishi Chaturvedi, Nick C. Fox, Sebastian J. Crutch, Marcus Richards, Jonathan M. Schott
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-21 (2024)
Abstract Background Although age is the biggest known risk factor for dementia, there remains uncertainty about other factors over the life course that contribute to a person’s risk for cognitive decline later in life. Furthermore, the pathological
Externí odkaz:
https://doaj.org/article/9fdd7c07f6e74bf4bc709c0fc60fb7cd
Autor:
Sarah-Naomi James, Carole Sudre, Nick C Fox, Marcus Richards, Alun Hughes, Josephine Barnes, Jonathan M Schott
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100262- (2024)
Introduction: Data drawn from the 1946 British birth cohort is opportunistically placed to address how midlife cardiac and vascular structure is linked with white matter brain health later in life, given that participants are born in the same week; h
Externí odkaz:
https://doaj.org/article/db444a48760f4e4183745a0cf24f8f18
Autor:
Mathijs Dijsselhof, Sarah- Naomi James, Luigi Lorenzini, Lyduine Collij, David Thomas, Catherine Scott, Emily Manning, Tamás Józsa, Dave Cash, Carole Sudre, Alun Hughes, Marcus Richards, Frederik Barkhof, Jonathan Schott, Jan Petr, Henk Mutsaerts
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100261- (2024)
Introduction: Mid-life cardiovascular and late-life structural cerebrovascular pathology play a major role in accelerating cognitive decline in normal aging and dementia. Cerebral blood flow (CBF) may be a critical intermediate biomarker of future co
Externí odkaz:
https://doaj.org/article/147f6d92988b40a5aa6337857f2680c3
Autor:
Sarah-Naomi James, Christopher A. Lane, Thomas D. Parker, Kirsty Lu, Jessica D. Collins, Heidi Murray-Smith, Michelle Byford, Andrew Wong, Ashvini Keshavan, Sarah Buchanan, Sarah E. Keuss, Diana Kuh, Nick C. Fox, Jonathan M. Schott, Marcus Richards
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-9 (2018)
Abstract Objective Identifying and recruiting people with early pre-symptomatic Alzheimer’s disease to neuroimaging research studies is increasingly important. The extent to which results of these studies can be generalised depends on the recruitme
Externí odkaz:
https://doaj.org/article/ba3b7ef34ae3429e973d5ecddf4dc1ef
Autor:
Louisa P. Needham, Kirsty Lu, Jennifer M. Nicholas, Jonathan M. Schott, Marcus Richards, Sarah-Naomi James
Publikováno v:
Maturitas. 170:31-38
Autor:
Sarah-Naomi James, Jennifer M. Nicholas, Kirsty Lu, Ashvini Keshavan, Christopher A. Lane, Thomas Parker, Sarah M. Buchanan, Sarah E. Keuss, Heidi Murray-Smith, Andrew Wong, David M. Cash, Ian B. Malone, Josephine Barnes, Carole H. Sudre, William Coath, Marc Modat, Sebastien Ourselin, Sebastian J. Crutch, Diana Kuh, Nick C. Fox, Jonathan M. Schott, Marcus Richards
Publikováno v:
Neurobiology of Aging, 122, 22-32. Elsevier Inc.
James, S-N, Nicholas, J M, Lu, K, Keshavan, A, Lane, C A, Parker, T, Buchanan, S M, Keuss, S E, Murray-Smith, H, Wong, A, Cash, D M, Malone, I B, Barnes, J, Sudre, C H, Coath, W, Modat, M, Ourselin, S, Crutch, S J, Kuh, D, Fox, N C, Schott, J M & Richards, M 2023, ' Adulthood cognitive trajectories over 26 years and brain health at 70 years of age : findings from the 1946 British Birth Cohort ', Neurobiology of Aging, vol. 122, pp. 22-32 . https://doi.org/10.1016/j.neurobiolaging.2022.10.003
James, S-N, Nicholas, J M, Lu, K, Keshavan, A, Lane, C A, Parker, T, Buchanan, S M, Keuss, S E, Murray-Smith, H, Wong, A, Cash, D M, Malone, I B, Barnes, J, Sudre, C H, Coath, W, Modat, M, Ourselin, S, Crutch, S J, Kuh, D, Fox, N C, Schott, J M & Richards, M 2023, ' Adulthood cognitive trajectories over 26 years and brain health at 70 years of age : findings from the 1946 British Birth Cohort ', Neurobiology of Aging, vol. 122, pp. 22-32 . https://doi.org/10.1016/j.neurobiolaging.2022.10.003
Few studies can address how adulthood cognitive trajectories relate to brain health in 70-year-olds. Participants (n = 468, 49% female) from the 1946 British birth cohort underwent 18F-Florbetapir PET/MRI. Cognitive function was measured in childhood
Autor:
Sarah Ann Mason, Lamia Al Saikhan, Siana Jones, Gemma Bale, Sarah-Naomi James, Heidi Murray-Smith, Alicja Rapala, Suzanne Williams, Brian Wong, Marcus Richards, Nick C. Fox, Rebecca Hardy, Jonathan M. Schott, Nish Chaturvedi, Alun D. Hughes
Publikováno v:
Artery Research, Vol 26, Iss 3 (2020)
The commonest causes of dementia are Alzheimer’s disease and vascular cognitive impairment. Although these conditions have been viewed as distinct entities, there is increasing evidence that neurodegenerative and vascular pathologies interact or ov
Externí odkaz:
https://doaj.org/article/f6806e0a4a4e4e698e54dbf739d2c814
Autor:
Thomas D. Parker, David M. Cash, Christopher A. Lane, Kirsty Lu, Ian B. Malone, Jennifer M. Nicholas, Sarah‐Naomi James, Ashvini Keshavan, Heidi Murray‐Smith, Andrew Wong, Sarah M. Buchanan, Sarah E. Keuss, Carole H. Sudre, David L. Thomas, Sebastian J. Crutch, Nick C. Fox, Marcus Richards, Jonathan M. Schott
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Cortical thickness has been proposed as a biomarker of Alzheimer's disease (AD)– related neurodegeneration, but the nature of its relationship with amyloid beta (Aβ) deposition and white matter hyperintensity volume (WMHV) in
Externí odkaz:
https://doaj.org/article/cd9606478e5d4d4c8b5a8c069934908e
Autor:
Kirsty Lu, Jennifer M. Nicholas, Sarah‐Naomi James, Christopher A. Lane, Thomas D. Parker, Ashvini Keshavan, Sarah E. Keuss, Sarah M. Buchanan, Heidi Murray‐Smith, David M. Cash, Carole H. Sudre, Ian B. Malone, William Coath, Andrew Wong, Susie M.D. Henley, Nick C. Fox, Marcus Richards, Jonathan M. Schott, Sebastian J. Crutch
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction We investigated whether life‐course factors and neuroimaging biomarkers of Alzheimer's disease pathology predict reaction time (RT) performance in older adults. Methods Insight 46 study participants, all born in the same week
Externí odkaz:
https://doaj.org/article/581b7ddff37a46509cc58782170ae19f