Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sarah N. Ur"'
Autor:
Alan MV West, Scott C Rosenberg, Sarah N Ur, Madison K Lehmer, Qiaozhen Ye, Götz Hagemann, Iracema Caballero, Isabel Usón, Amy J MacQueen, Franz Herzog, Kevin D Corbett
Publikováno v:
eLife, Vol 8 (2019)
The meiotic chromosome axis plays key roles in meiotic chromosome organization and recombination, yet the underlying protein components of this structure are highly diverged. Here, we show that ‘axis core proteins’ from budding yeast (Red1), mamm
Externí odkaz:
https://doaj.org/article/5350bcb920d349cb80368c93e6ea6f6e
Autor:
Carolyn R. Milano, Sarah N. Ur, Yajie Gu, Eelco C. Tromer, Jessie Zhang, Andreas Hochwagen, Kevin D. Corbett
The meiotic chromosome axis coordinates chromosome organization and interhomolog recombination in meiotic prophase and is essential for fertility. InS. cerevisiae, the HORMAD protein Hop1 mediates enrichment of axis proteins at nucleosome-rich genomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b62f1158af6aa2b439c56ccc8685830
https://doi.org/10.1101/2023.03.04.531117
https://doi.org/10.1101/2023.03.04.531117
Autor:
Kevin D. Corbett, Sarah N. Ur
Publikováno v:
Annual Review of Genetics. 55:497-526
The specialized two-stage meiotic cell division program halves a cell's chromosome complement in preparation for sexual reproduction. This reduction in ploidy requires that in meiotic prophase, each pair of homologous chromosomes (homologs) identify
Publikováno v:
Protein Sci
The widespread CBASS (cyclic oligonucleotide‐based anti‐phage signaling system) immune systems in bacteria protect their hosts from bacteriophage infection by triggering programmed cell death. CBASS systems all encode a cyclic oligonucleotide syn
Autor:
Qishan Liang, Sara T. Richey, Chelsea Blankenchip, Sarah N. Ur, Qiaozhen Ye, Rebecca K. Lau, Kevin D. Corbett
Publikováno v:
Biophysical Journal. 122:215a
Autor:
Jonna Heldrich, Carolyn R. Milano, Tovah E. Markowitz, Sarah N. Ur, Luis A. Vale-Silva, Kevin D. Corbett, Andreas Hochwagen
Successful meiotic recombination, and thus fertility, depends on conserved axis proteins that organize chromosomes into arrays of anchored chromatin loops and provide a protected environment for DNA exchange. Here, we show that the stereotypic chromo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7bdb03e34e00d6a06cbf203570cd41e
https://doi.org/10.1101/2020.08.11.247122
https://doi.org/10.1101/2020.08.11.247122
Autor:
Qiaozhen Ye, Madison K Lehmer, Scott C. Rosenberg, Iracema Caballero, Isabel Usón, Amy J. MacQueen, Götz Hagemann, Kevin D. Corbett, Alan M V West, Franz Herzog, Sarah N. Ur
Publikováno v:
eLife
Digital.CSIC. Repositorio Institucional del CSIC
instname
eLife, Vol 8 (2019)
Digital.CSIC. Repositorio Institucional del CSIC
instname
eLife, Vol 8 (2019)
The meiotic chromosome axis plays key roles in meiotic chromosome organization and recombination, yet the underlying protein components of this structure are highly diverged. Here, we show that 'axis core proteins' from budding yeast (Red1), mammals
Autor:
Götz Hagemann, Iracema Caballero, Scott C. Rosenberg, Isabel Usón, Kevin D. Corbett, Madison K Lehmer, Alan M V West, Amy J. MacQueen, Qiaozhen Ye, Franz Herzog, Sarah N. Ur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b88c1490f37d7330355675293530005
https://doi.org/10.7554/elife.40372.040
https://doi.org/10.7554/elife.40372.040
Publikováno v:
Gene therapy, vol 21, iss 6
Rocca, CJ; Ur, SN; Harrison, F; & Cherqui, S. (2014). RAAV9 combined with renal vein injection is optimal for kidney-targeted gene delivery: Conclusion of a comparative study. Gene Therapy, 21(6), 618-628. doi: 10.1038/gt.2014.35. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/9437z8cr
Gene therapy
Rocca, CJ; Ur, SN; Harrison, F; & Cherqui, S. (2014). RAAV9 combined with renal vein injection is optimal for kidney-targeted gene delivery: Conclusion of a comparative study. Gene Therapy, 21(6), 618-628. doi: 10.1038/gt.2014.35. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/9437z8cr
Gene therapy
Effective gene therapy strategies for the treatment of kidney disorders remain elusive. We report an optimized kidney-targeted gene delivery strategy using recombinant adeno-associated virus (rAAV) administered via retrograde renal vein injection in
Publikováno v:
The EMBO journal. 35(19)
In budding yeast, the monopolin complex mediates sister kinetochore cross‐linking and co‐orientation in meiosis I. The CK1δ kinase Hrr25 is critical for sister kinetochore co‐orientation, but its roles are not well understood. Here, we present