Výsledky vyhledávání - "Sarah N. Statt"

A genetic enrichment strategy for delay of onset of Alzheimer’s disease clinical trials

Autor: Daniel K. Burns, Scott Marshall, Ann M. Saunders, Emiliangelo Ratti, Sarah N. Statt, Eric Lai, Meredith Culp, Tom Swanson, Bernard F. Andruss, Scott S. Sundseth, Carl Chiang, Tobi Guennel, Bradley Hall, Craig A. Metz, Gary J. Latham, Michael W. Lutz, Stephen Haneline, Robert Alexander, David Yarnall

Publikováno v: Alzheimer's & Dementia. 16

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41d84fd3d71adfba01f2581899ad3588
https://doi.org/10.1002/alz.044920

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A combination of long-range PCR and long-read sequencing resolves common, high-risk dark and camouflaged carrier screening genes

Autor: Gary J. Latham, Julie R. Thibert, Cody Edwards, John Harting, Jacob Wisotsky, Theodore Markulin, Jon Kemppainen, Brian C. Haynes, Cheryl Heiner, Sarah N. Statt, Liangjing Chen

Publikováno v: Molecular Genetics and Metabolism. 132:S238-S239

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::27bf436513ebaddb8c5f11d48e2907a1
https://doi.org/10.1016/s1096-7192(21)00452-2

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A Novel Triplet-Primed PCR Assay to Detect the Full Range of Trinucleotide CAG Repeats in the Huntingtin Gene (HTT)

Autor: Sergio Fanelli, Julie R. Thibert, Annunziata Morella, Federica Consoli, Ferdinando Squitieri, Sarah N. Statt, Alessandro De Luca, Gary J. Latham

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1689, p 1689 (2021)

The expanded CAG repeat number in HTT gene causes Huntington disease (HD), which is a severe, dominant neurodegenerative illness. The accurate determination of the expanded allele size is crucial to confirm the genetic status in symptomatic and presy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6300a7a2c432e8043d737471ecce3350
https://doi.org/10.3390/ijms22041689

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[P1–270]: A STREAMLINED PCR‐BASED FRAGMENT ANALYSIS ASSAY THAT RESOLVES BOTH SINGLE NUCLEOTIDE AND POLY‐T LENGTH POLYMORPHISMS AT APOE AND TOMM40 SUSCEPTIBILITY LOCI IN ALZHEIMER's DISEASE

Autor: Bradley Hall, Gary J. Latham, Julie R. Thibert, Jacob Wisotsky, Sarah N. Statt, Jon Kemppainen

Publikováno v: Alzheimer's & Dementia. 13

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b5b04ea0be39a546905e7b4a6ac90c9e
https://doi.org/10.1016/j.jalz.2017.06.286

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[P3–072]: MULTI‐SITE EVALUATION OF THE AMPLIDEX® PCR/CE TOMM40 KIT FOR RAPID AND ACCURATE GENOTYPING OF POLY‐T LENGTH POLYMORPHISMS AT RS10524523 OF THE TOMM40 GENE

Autor: Gary J. Latham, Sarah N. Statt, EunRan Suh, Julie R. Thibert, Vivianna M. Van Deerlin

Publikováno v: Alzheimer's & Dementia. 13

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a5c16e33c915d3ab20fb5aaadebdd2dd
https://doi.org/10.1016/j.jalz.2017.06.1282

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Abstract 5574: A comprehensive, targeted next-generation sequencing method that rapidly and accurately detects circulating tumor DNA variants at 0.1% frequency in plasma samples

Autor: Blake Printy, Yves Konigshofer, Farol L. Tomson, Jessica L. Larson, Gary J. Latham, Brian C. Haynes, Sarah N. Statt, Jeffrey Shelton, Liangjing Chen, Joseph K. Kaplan, Shobha Gokul, Lando Ringel

Publikováno v: Cancer Research. 78:5574-5574

Introduction: Mutation analysis of circulating tumor DNA (ctDNA) in blood-based liquid biopsies provides a minimally invasive approach to detect and monitor disease. Existing next-generation sequencing (NGS) liquid biopsy techniques have laborious an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63b5c569e834e2e55d637501a8dae4da
https://doi.org/10.1158/1538-7445.am2018-5574

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