Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sarah N. Rampersad"'
Publikováno v:
Cellular Signalling. 28:741-748
Although cAMP-signalling regulates numerous functions of vascular endothelial cells (VECs), including their ability to impact vascular resistance in response to changes in blood flow dynamics, few of the mechanisms underlying these effects have yet t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e58013e38ee30eb8736772cf80615e9
https://doi.org/10.1016/j.cellsig.2015.12.001
https://doi.org/10.1016/j.cellsig.2015.12.001
Publikováno v:
The American Journal of Pathology. 179:1549-1559
Because both endothelin-1 (ET-1) and angiotensin II (AngII) are independent mediators of arterial remodeling, we sought to determine the role of ET receptor inhibition in AngII-accelerated atherosclerosis and aortic aneurysm formation. We administere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058f9c8e4b03d6011c5587251dafa561
https://doi.org/10.1016/j.ajpath.2011.05.014
https://doi.org/10.1016/j.ajpath.2011.05.014
Autor:
Miles D. Houslay, Martin J. Lynch, Elaine Huston, Jeffrey D. Ovens, Donald H. Maurice, Lindsay S. Wilson, Stuart J. Netherton, M. Bibiana Umana, Sarah N. Rampersad, George S. Baillie
Publikováno v:
Journal of Biological Chemistry. 285:33614-33622
Vascular endothelial cell (VEC) permeability is largely dependent on the integrity of vascular endothelial cadherin (VE-cadherin or VE-Cad)-based intercellular adhesions. Activators of protein kinase A (PKA) or of exchange protein activated by cAMP (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb77e948e073f914aec1de5a29c1cfc
https://doi.org/10.1074/jbc.m110.140004
https://doi.org/10.1074/jbc.m110.140004
Autor:
Sarah N. Rampersad, Paulina Brzezinska, M. Bibiana Umana, Donald H. Maurice, Fabien Hubert, Alie Wudwud, Nathalie Butler, Silja I. Freitag
Publikováno v:
Cellular signalling. 28(6)
Blood flow-associated fluid shear stress (FSS) dynamically regulates the endothelium's ability to control arterial structure and function. While arterial endothelial cells (AEC) subjected to high levels of laminar FSS express a phenotype resistant to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4623e212f1b85c22ff0d29fb8247a9
https://pubmed.ncbi.nlm.nih.gov/26979996
https://pubmed.ncbi.nlm.nih.gov/26979996
Publikováno v:
Molecular genetics and genomics : MGG. 290(6)
Ribosomal protein genes occasionally undergo successful migration from the mitochondrion to the nucleus in flowering plants and we previously presented evidence that the S19 ribosomal protein gene (rps19) had been transferred to the nucleus in the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204ab49daa821fa6d6227583d6527070
https://pubmed.ncbi.nlm.nih.gov/26141567
https://pubmed.ncbi.nlm.nih.gov/26141567
Autor:
Fabien Hubert, Donald H. Maurice, M Umana, Silja I. Freitag, Nathalie Butler, Paulina Brzezinska, Alie Wudwud, Sarah N. Rampersad
Publikováno v:
The FASEB Journal. 29
Herein, we report a novel role for cAMP-signaling in human aortic endothelial cell (HAEC) adaptation to fluid-mediated shear stress (FSS). Our results showed that increases in cAMP enhanced elongat...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9bbdd2d829158e14a7a5e41868c6c38
https://doi.org/10.1096/fasebj.29.1_supplement.625.2
https://doi.org/10.1096/fasebj.29.1_supplement.625.2
Publikováno v:
The FASEB Journal. 28
Vascular smooth muscle cells (VSMCs) are differentiated and quiescent (contracile phenotype) in adult blood vessels. In contrast, VSMCs can become activated and highly proliferative and migratory (...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a69ce7ad51335d60ab3b17367a700cd
https://doi.org/10.1096/fasebj.28.1_supplement.1065.6
https://doi.org/10.1096/fasebj.28.1_supplement.1065.6
Autor:
Paulina Brzezinska, M Umana, Fabien Hubert, Alie Wudwud, Donald H. Maurice, Sarah N. Rampersad, Silja I. Freitag
Publikováno v:
The FASEB Journal. 28
Vascular myocyte (VSMC) migration is a vital process allowing for the regulation of vascular development, tissue repair and the modulation of pathophysiological conditions including atherosclerosis. Atherosclerosis induced damage to the vascular endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b292e74bfebacd222b0b11342bf1e17
https://doi.org/10.1096/fasebj.28.1_supplement.1065.3
https://doi.org/10.1096/fasebj.28.1_supplement.1065.3
Autor:
Alie Wudwud, M Umana, Fabien Hubert, Donald H. Maurice, Paulina Brzezinska, Sarah N. Rampersad, Silja I. Freitag
Publikováno v:
The FASEB Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccd5121e625ba89b49e5b843733b0167
https://doi.org/10.1096/fasebj.28.1_supplement.851.14
https://doi.org/10.1096/fasebj.28.1_supplement.851.14
Autor:
Paulina Brzezinska, Sarah N. Rampersad, Fabien Hubert, Donald H. Maurice, Lindsay S. Wilson, M. Bibiana Umana, Milosz Kaczmarek, Tammy K. Truong, Alie Wudwud, Silja I. Freitag
Publikováno v:
Biochemical Society transactions. 42(2)
The cyclic nucleotide second messengers cAMP and cGMP each affect virtually all cellular processes. Although these hydrophilic small molecules readily diffuse throughout cells, it is remarkable that their ability to activate their multiple intracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454c229a3e099b3e00d31f25981f75b1
https://pubmed.ncbi.nlm.nih.gov/24646226
https://pubmed.ncbi.nlm.nih.gov/24646226