Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sarah N. Motz"'
Autor:
Jitra Kriangkum, Sarah N Motz, Tanner Mack, Sara Beiggi, Eva Baigorri, Hemalatha Kuppusamy, Andrew R Belch, James B Johnston, Linda M Pilarski
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137232 (2015)
The immunoglobulin heavy chain (IGH) gene rearrangement in chronic lymphocytic leukemia (CLL) provides a unique molecular signature; however, we demonstrate that 26/198 CLL patients (13%) had more than one IGH rearrangement, indicating the power of m
Externí odkaz:
https://doaj.org/article/7f4617d9519e44029a8c3809cf2e4678
Autor:
Jitra Kriangkum, Sarah N Motz, Carina S Debes Marun, Sandrine T Lafarge, Spencer B Gibson, Christopher P Venner, James B Johnston, Andrew R Belch, Linda M Pilarski
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64927 (2013)
Clonal diversity in multiple myeloma (MM) includes both MM-related and MM-unrelated clonal expansions which are subject to dominance exerted by the MM clone. Here we show evidence for the existence of minor but highly expanded unrelated B-cell clones
Externí odkaz:
https://doaj.org/article/8f7197a1402f47988aaf48a320c703d0
Autor:
Sara Beiggi, James B. Johnston, Tanner Mack, Linda M. Pilarski, Jitra Kriangkum, Hemalatha Kuppusamy, Sarah N. Motz, Eva Baigorri, Andrew Belch
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137232 (2015)
PLoS ONE
PLoS ONE
The immunoglobulin heavy chain (IGH) gene rearrangement in chronic lymphocytic leukemia (CLL) provides a unique molecular signature; however, we demonstrate that 26/198 CLL patients (13%) had more than one IGH rearrangement, indicating the power of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2efd782c166dd246b878343b81024ec
http://europepmc.org/articles/PMC4564241?pdf=render
http://europepmc.org/articles/PMC4564241?pdf=render
Autor:
Jitra Kriangkum, Julia Kirshner, Kyle J. Thulien, Sarah N. Motz, Andrew Belch, Linda M. Pilarski
Publikováno v:
Leukemialymphoma. 52(2)
A small percentage of cases of Waldenstrom macroglobulinemia (WM) present with biclonality, defined here as the rearrangement of two distinct VDJ gene segments. Here we investigated the expansion of two clones from a patient with WM expressing molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eeb1d445ba627457fb818f0fd529bc1
https://pubmed.ncbi.nlm.nih.gov/21133724
https://pubmed.ncbi.nlm.nih.gov/21133724
Publikováno v:
Blood. 116:2981-2981
Abstract 2981 Typically MM involves a single monoclonal protein, predicting a single CDR3 peak. We have shown that a sizeable number of patients do not fit this pattern. RT-PCR and genomic PCR (gPCR) were performed using universal primers that bind t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc8551cad06ef681fa2a1f343a6373c2
https://doi.org/10.1182/blood.v116.21.2981.2981
https://doi.org/10.1182/blood.v116.21.2981.2981
Publikováno v:
Blood. 114:1813-1813
Abstract 1813 Poster Board I-839 Malignant clones in multiple myeloma (MM) express unique clonotypic VDJ sequences associated with the clinical isotype. It has been widely assumed that MM patients have only one clone. However, our analysis reveals th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6aa10d2bd276dc74f365ee8661cec0f
https://doi.org/10.1182/blood.v114.22.1813.1813
https://doi.org/10.1182/blood.v114.22.1813.1813