Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Sarah N Deffit"'
Autor:
Sarah N Deffit, Brian A Yee, Aidan C Manning, Suba Rajendren, Pranathi Vadlamani, Emily C Wheeler, Alain Domissy, Michael C Washburn, Gene W Yeo, Heather A Hundley
Publikováno v:
eLife, Vol 6 (2017)
ADAR proteins alter gene expression both by catalyzing adenosine (A) to inosine (I) RNA editing and binding to regulatory elements in target RNAs. Loss of ADARs affects neuronal function in all animals studied to date. Caenorhabditis elegans lacking
Externí odkaz:
https://doaj.org/article/0be709163d094d89ae3e71f8c13c24d9
Autor:
Suba Rajendren, Alfa Dhakal, Jack Townsend, Sarah N. Deffit, Pranathi Vadlamani, Heather A. Hundley
Publikováno v:
Genome Res
Adenosine (A) to inosine (I) RNA editing contributes to transcript diversity and modulates gene expression in a dynamic, cell type–specific manner. During mammalian brain development, editing of specific adenosines increases, whereas the expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c92e4350118d11700b1b9e0baed87a
https://europepmc.org/articles/PMC7849389/
https://europepmc.org/articles/PMC7849389/
Autor:
Gail J Gardiner, Sarah N Deffit, Shawna eMcLetchie, Liliana ePérez, Crystal C Walline, Janice S Blum
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
The nicotinamide adenine dinucleotide phosphate (NADPH) oxidase expressed in phagocytes is a multi-subunit enzyme complex that generates superoxide (O2.-). This radical is an important precursor of hydrogen peroxide (H2O2) and other reactive oxygen s
Externí odkaz:
https://doaj.org/article/00925d87b48b4dbbad61dd66c53af474
Publikováno v:
The American Biology Teacher. 79:661-667
The use of primary scientific inquiry and experimentation to develop students’ understanding of methodologies used by scientists and the nature of science is a key component of the Next-Generation Science Standards (NGSS). Introduction to inquiry-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50e982fd14c07722ab5e6ec2720fd13f
https://doi.org/10.1525/abt.2017.79.8.661
https://doi.org/10.1525/abt.2017.79.8.661
Autor:
Nabeel S. Ganem, Aidan C. Manning, Einav Mantsur, Emily C. Wheeler, Ayelet T. Lamm, Noa Ben-Asher, Orna Ben-Naim Zgayer, Heather A. Hundley, Michael C. Washburn, Sarah N. Deffit, Gene W. Yeo
Publikováno v:
Cell reports
SUMMARY A-to-I RNA editing, catalyzed by ADAR proteins, is widespread in eukaryotic transcriptomes. Studies showed that, in C. elegans, ADR-2 can actively deaminate dsRNA, whereas ADR-1 cannot. Therefore, we set out to study the effect of each of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e3a39934921ef5e5b737b98b17689d
https://pubmed.ncbi.nlm.nih.gov/31018137
https://pubmed.ncbi.nlm.nih.gov/31018137
Autor:
Heather A. Hundley, Sarah N. Deffit
Publikováno v:
WIREs RNA. 7:113-127
Hundreds to millions of adenosine (A)-to-inosine (I) modifications are present in eukaryotic transcriptomes and play an essential role in the creation of proteomic and phenotypic diversity. As adenosine and inosine have different base-pairing propert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e5d009917072b7cdebddb67467a0eb6
https://doi.org/10.1002/wrna.1319
https://doi.org/10.1002/wrna.1319
Autor:
Michael C. Washburn, Emily C. Wheeler, Sarah N. Deffit, Suba Rajendren, Brian A. Yee, Alain Domissy, Gene W. Yeo, Pranathi Vadlamani, Aidan C. Manning, Heather A. Hundley
Publikováno v:
eLife, Vol 6 (2017)
DNA is the blueprint that tells each cell in an organism how it should operate. It encodes the instructions to make proteins and other molecules. To make a protein, a section of DNA known as a gene is used as a template to make molecules known as mes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8155bb622cdae2af9dbfa65c0a542346
https://doi.org/10.7554/elife.28625
https://doi.org/10.7554/elife.28625
Autor:
Sarah N Deffit, Brian A Yee, Aidan C Manning, Suba Rajendren, Pranathi Vadlamani, Emily C Wheeler, Alain Domissy, Michael C Washburn, Gene W Yeo, Heather A Hundley
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cc14afe1d133666045c8a2301d3d4b8
https://doi.org/10.7554/elife.28625.018
https://doi.org/10.7554/elife.28625.018
Autor:
Sarah N, Deffit, Brian A, Yee, Aidan C, Manning, Suba, Rajendren, Pranathi, Vadlamani, Emily C, Wheeler, Alain, Domissy, Michael C, Washburn, Gene W, Yeo, Heather A, Hundley
Publikováno v:
eLife
ADAR proteins alter gene expression both by catalyzing adenosine (A) to inosine (I) RNA editing and binding to regulatory elements in target RNAs. Loss of ADARs affects neuronal function in all animals studied to date. Caenorhabditis elegans lacking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a82fcfa90aabd4f7c53d362ee0e66683
https://pubmed.ncbi.nlm.nih.gov/28925356
https://pubmed.ncbi.nlm.nih.gov/28925356