A Multitubular Kidney-on-Chip to Decipher Pathophysiological Mechanisms in Renal Cystic Diseases

Autor: Sarah Myram, Bastien Venzac, Brice Lapin, Aude Battistella, Fanny Cayrac, Bertrand Cinquin, Charles Cavaniol, Giacomo Gropplero, Isabelle Bonnet, Sophie Demolombe, Stéphanie Descroix, Sylvie Coscoy

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a major renal pathology provoked by the deletion of PKD1 or PKD2 genes leading to local renal tubule dilation followed by the formation of numerous cysts, ending up with renal failure in adultho

Externí odkaz: https://doaj.org/article/228122e82c43454b8846384e590894c0

Engineering small tubes with changes in diameter for the study of kidney cell organization

Autor: Jean-Louis Viovy, Ludovic Leconte, Taous Benarab, Bastien Venzac, Sylvain Monnier, Stéphanie Descroix, Sarah Myram, Sylvie Coscoy, Randa Madoun, Fanny Cayrac, François Amblard

Publikováno v: Biomicrofluidics
Biomicrofluidics, American Institute of Physics, 2018, 12 (2), pp.024114. ⟨10.1063/1.5025027⟩
Biomicrofluidics, 2018, 12 (2), pp.024114. ⟨10.1063/1.5025027⟩

International audience; Multicellular tubes are structures ubiquitously found during development and in adult organisms. Their topologies (diameter, direction or branching), together with their mechanical characteristics, play fundamental roles in or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75d6ce7d618e262d969a42d5ffa1fb0
https://doi.org/10.1063/1.5025027