New Insights into the Role of PPARγ in Skin Physiopathology

Autor: Stefania Briganti, Sarah Mosca, Anna Di Nardo, Enrica Flori, Monica Ottaviani

Publikováno v: Biomolecules, Vol 14, Iss 6, p 728 (2024)

Peroxisome proliferator-activated receptor gamma (PPARγ) is a transcription factor expressed in many tissues, including skin, where it is essential for maintaining skin barrier permeability, regulating cell proliferation/differentiation, and modulat

Externí odkaz: https://doaj.org/article/73f4af5f9a944f16856505bab4f45d0e

The αMSH-Dependent PI3K Pathway Supports Energy Metabolism, via Glucose Uptake, in Melanoma Cells

Autor: Giorgia Cardinali, Daniela Kovacs, Sarah Mosca, Barbara Bellei, Enrica Flori, Aldo Morrone, Anna Maria Mileo, Vittoria Maresca

Publikováno v: Cells, Vol 12, Iss 7, p 1099 (2023)

Stimulation of melanocytes and murine melanoma cells with αMSH plus the PI3K inhibitor LY294002 resulted in ROS increase, oxidative DNA damage, and pigment retention. We performed cellular and molecular biology assays (Western blot, FACS, immunofluo

Externí odkaz: https://doaj.org/article/993c6cb220b14dc9b612695a2a85ae7c

Sebocytes contribute to melasma onset

Autor: Enrica Flori, Arianna Mastrofrancesco, Sarah Mosca, Monica Ottaviani, Stefania Briganti, Giorgia Cardinali, Angela Filoni, Norma Cameli, Marco Zaccarini, Christos C. Zouboulis, Mauro Picardo

Publikováno v: iScience, Vol 25, Iss 3, Pp 103871- (2022)

Summary: Melasma is a hyperpigmentary disorder with photoaging features, whose manifestations appear on specific face areas, rich in sebaceous glands (SGs). To explore the SGs possible contribution to the onset, the expression of pro-melanogenic and

Externí odkaz: https://doaj.org/article/8067f5c3a8b54b279d1598a060ea7d08

The PI3K pathway induced by αMSH exerts a negative feedback on melanogenesis and contributes to the release of pigment

Autor: Giorgia Cardinali, Vittoria Maresca, Stefania Briganti, Sarah Mosca, Enrica Flori, Anna Maria Mileo, Irene Bottillo

Publikováno v: Pigment cellmelanoma researchREFERENCES. 34(1)

The melanocortin-1 receptor (MC1R) belongs to the family of the G protein-coupled receptor (GPCR). Activated GPCRs can promote the phosphoinositide 3-kinase (PI3K) pathway. Few studies deal with the role of the PI3K pathway activation in response to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc671b5ea321c7eff144274ef9d74aba
https://pubmed.ncbi.nlm.nih.gov/32608114

Enfants confiés aux proches : comparaison France - Italie

Autor: Livia Cadei, Bernadette Tillard, Chiara Sità, Sarah Mosca

Publikováno v: Revue internationale de l'éducation familiale
Revue internationale de l'éducation familiale, L'Harmattan, 2018, La Revue Internationale de l'Education Familiale
Revue internationale de l'éducation familiale, L'Harmattan, 2018, Familles en contextes de vulnérabilités psychosociales : réalités des enfants, des parents et des services, pp.23-45. ⟨10.3917/rief.043.0023⟩
La Revue Internationale de l'Education Familiale
La Revue Internationale de l'Education Familiale, 2018, La Revue Internationale de l'Education Familiale, 43, pp.23-45
Revue internationale de l'éducation familiale, L'Harmattan, 2018
Revue internationale de l'éducation familiale, 2018
Revue internationale de l'éducation familiale, 2018, Familles en contextes de vulnérabilités psychosociales : réalités des enfants, des parents et des services, 43, pp.23-45. ⟨10.3917/rief.043.0023⟩
Revue internationale de l'éducation familiale, 2018, La Revue Internationale de l'Education Familiale

L ’implication de la famille élargie et du réseau social des familles est un objet peu exploré en France comme en Italie. Cet article se focalise sur cette forme de suppléance familiale dans chacun de ces deux pays. Après avoir présenté les

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372e53e7f78845ffb612e59c7563e447
https://hal.univ-lille.fr/hal-01955419/file/France-Italie-ACL2017-11-15.pdf