Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive, HER2-negative breast cancer (FAKTION): overall survival, updated progression-free survival, and expanded biomarker analysis from a randomised, phase 2 trial

Autor: Sacha J Howell, Angela Casbard, Margherita Carucci, Kate Ingarfield, Rachel Butler, Sian Morgan, Magdalena Meissner, Catherine Bale, Pavel Bezecny, Sarah Moon, Chris Twelves, Ramachandran Venkitaraman, Simon Waters, Elza C de Bruin, Gaia Schiavon, Andrew Foxley, Robert H Jones

Publikováno v: Howell, S J, Casbard, A, Carucci, M, Ingarfield, K, Butler, R, Morgan, S, Meissner, M, Bale, C, Bezecny, P, Moon, S, Twelves, C, Venkitaraman, R, Waters, S, de Bruin, E C, Schiavon, G, Foxley, A & Jones, R H 2022, ' Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive, HER2-negative breast cancer (FAKTION) : overall survival, updated progression-free survival, and expanded biomarker analysis from a randomised, phase 2 trial ', The Lancet. Oncology, vol. 23, no. 7, pp. 851-864 . https://doi.org/10.1016/S1470-2045(22)00284-4

BACKGROUND: Capivasertib, an AKT inhibitor, added to fulvestrant, was previously reported to improve progression-free survival in women with aromatase inhibitor-resistant oestrogen receptor (ER)-positive, HER2-negative advanced breast cancer. The ben

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8b7c1cc7c7d91a6ed98ec5f578778f
https://doi.org/10.1016/s1470-2045(22)00284-4

Quality Indicators for Transition from Pediatric to Adult Care for Youth With Chronic Conditions: Proposal for an Online Modified Delphi Study

Autor: Alene Toulany, Dmitry Khodyakov, Sarah Mooney, Lisa Stromquist, Katherine Bailey, Claire EH Barber, Michelle Batthish, Kristin Cleverley, Gina Dimitropoulos, Jan Willem Gorter, Danijela Grahovac, Ruth Grimes, Beverly Guttman, Michèle L Hébert, Tomisin John, Lisha Lo, Dorothy Luong, Laura MacGregor, Geetha Mukerji, Jacklynn Pidduck, Vjura Senthilnathan, Rayzel Shulman, Patricia Trbovich, Sarah EP Munce

Publikováno v: JMIR Research Protocols, Vol 13, p e60860 (2024)

BackgroundThe transition from pediatric to adult care poses a significant health system–level challenge impeding the delivery of quality health services for youth with chronic health conditions. In Canada and globally, the transition to adult care

Externí odkaz: https://doaj.org/article/ca0853d8e7874f5cb9a3707a59e54450

Mainstreaming germline BRCA1/2 testing in non-mucinous epithelial ovarian cancer in the North West of England

Autor: Andrew R Clamp, Gordon C Jayson, Martin Hogg, Sarah Moon, Doina Badea, Helene Schlecht, Fiona Lalloo, Elaine F. Harkness, Jurjees Hasan, Nicola Flaum, Dennis Hadjiyiannakis, Tara Clancy, Andrew J Wallace, George J Burghel, Claire Mitchell, Richard J. Edmondson, Robert D. Morgan, Emma J Crosbie, M Bulman, Emma R. Woodward, D. Gareth Evans

Publikováno v: Eur J Hum Genet

Poly(ADP-ribose) polymerase (PARP) inhibitors improve survival in BRCA-mutant high-grade serous ovarian carcinoma. As a result, germline and somatic BRCA1/2 testing has become standard practice in women diagnosed with ovarian cancer. We outline chang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fde76bae880cf2e9e8baf636fc4a23f
https://doi.org/10.1038/s41431-020-0692-y

"If we are Asian, then are we funny?": Margaret Cho's "All-American Girl" as the First (and Last?) Asian American Sitcom

Autor: Cassinelli, Sarah Moon

Publikováno v: Studies in American Humor, 2008 Jan 01(17), 131-144.

Externí odkaz: https://www.jstor.org/stable/42573541

Writing Democracy: The Political Turn in and Beyond the Trump Era

Autor: Sarah Moon

Publikováno v: Community Literacy Journal. 15

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b2113a1e55f2133389816433907f623
https://doi.org/10.25148/clj.15.1.009374