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Autor:
Terzah M. Horton, Sharon Bergeron, Emasenyie Isikwei, Joel M. Reid, Charles G. Minard, Sarah Menig, Brenda J. Weigel, Elizabeth Fox, Xiaowei Liu, Katherine Tarlock, Todd M. Cooper
Publikováno v:
Journal of Clinical Oncology. 39:10018-10018
10018 Background: Outcomes for children with relapsed/refractory (R/R) AML and MDS are poor and new therapies are needed. Pevonedistat is an inhibitor of the NEDD-8 activating enzyme, a key regulator of the ubiquitin proteasome system that is respons