Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sarah Martinez Roth"'
Autor:
Megan E. McNamara, Netanel Loyfer, Amber J. Kiliti, Marcel O. Schmidt, Sapir Shabi-Porat, Sidharth S. Jain, Sarah Martinez Roth, A. Patrick McDeed IV, Nesreen Shahrour, Elizabeth Ballew, Yun-Tien Lin, Heng-Hong Li, Anne Deslattes Mays, Sonali Rudra, Anna T. Riegel, Keith Unger, Tommy Kaplan, Anton Wellstein
Publikováno v:
JCI Insight, Vol 8, Iss 14 (2023)
Radiation therapy is an effective cancer treatment, although damage to healthy tissues is common. Here we analyzed cell-free, methylated DNA released from dying cells into the circulation to evaluate radiation-induced cellular damage in different tis
Externí odkaz:
https://doaj.org/article/0eb9bcb8aa8b40a4ba4c47c4e39aa949
Autor:
Sarah Martinez Roth, Eveline E. Vietsch, Megan E. Barefoot, Marcel O. Schmidt, Matthew D. Park, Archana Ramesh, Michael R. Lindberg, Giuseppe Giaccone, Anna T. Riegel, Ana Barac, Keith Unger, Anton Wellstein
Publikováno v:
Gastrointestinal Disorders, Vol 3, Iss 3, Pp 100-112 (2021)
Thoracic high-dose radiation therapy (RT) for cancer has been associated with early and late cardiac toxicity. To assess altered rates of cardiomyocyte cell death due to RT we monitored changes in cardiomyocyte-specific, cell-free methylated DNA (cfD
Externí odkaz:
https://doaj.org/article/44f090ede39b42859e5a5e78d9c4ff96
Autor:
Megan E. Barefoot, Netanel Loyfer, Amber J. Kiliti, Marcel O. Schmidt, Sapir Shabi-Porat, Sidharth Jain, Sarah Martinez Roth, A. Patrick McDeed, Nesreen Shahrour, Elizabeth Ballew, Yun-Tien Lin, Heng-Hong Li, Anne Deslattes Mays, Sonali Rudra, Anna T. Riegel, Keith Unger, Tommy Kaplan, Anton Wellstein
Radiation therapy is an effective cancer treatment although damage to healthy tissues is common. Here we characterize the methylomes of healthy human and mouse tissues to establish sequencing-based, cell-type specific reference DNA methylation atlase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cf636d536fd4c82418cea0d19b0e95c
https://doi.org/10.1101/2022.04.12.487966
https://doi.org/10.1101/2022.04.12.487966
Autor:
Archana Ramesh, Giuseppe Giaccone, Marcel O. Schmidt, Anna T. Riegel, Ana Barac, Sarah Martinez Roth, Eveline E. Vietsch, Megan E. Barefoot, Keith Unger, Matthew D. Park, Michael R. Lindberg, Anton Wellstein
Publikováno v:
Gastrointestinal Disorders
Volume 3
Issue 3
Pages 11-112
Gastrointestinal Disorders, Vol 3, Iss 11, Pp 100-112 (2021)
Volume 3
Issue 3
Pages 11-112
Gastrointestinal Disorders, Vol 3, Iss 11, Pp 100-112 (2021)
Thoracic high-dose radiation therapy (RT) for cancer has been associated with early and late cardiac toxicity. To assess altered rates of cardiomyocyte cell death due to RT we monitored changes in cardiomyocyte-specific, cell-free methylated DNA (cfD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1014602ccf7c8352e4fd4db3759b8c
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071613498
Methods in Molecular Biology ISBN: 9781071613498
Cancer cell vascular invasion and extravasation at metastatic sites are hallmarks of malignant progression of cancer and associated with poor disease outcome. Here we describe an in vivo approach to study the invasive ability of cancer cells into the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ef553bf4805ab7c99121021c5783cc
https://pubmed.ncbi.nlm.nih.gov/33742390
https://pubmed.ncbi.nlm.nih.gov/33742390
Autor:
Sarah Martinez Roth
Publikováno v:
Cancer Research. 79:2912A-2912A
Cancer cells are subjected to evolutionary selection and adaptation of clonal populations by changes in the tumor and metastatic microenvironment as well as their response to drug treatment. We wished to evaluate how this tumor heterogeneity impacts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2f6fe369a46d7ef6a9caf0772762114
https://doi.org/10.1158/1538-7445.am2019-2912a
https://doi.org/10.1158/1538-7445.am2019-2912a
Autor:
Sarah Martinez Roth, Elana J. Fertig, Dalal AlDeghaither, Sandra A. Jablonski, Joseph C. Murray, Louis M. Weiner, Shaojun Tang
Publikováno v:
Cancer Research. 77:633-633
Antibody dependent cellular cytotoxicity (ADCC) is one mechanism by which monoclonal antibodies (mAb) work. In addition to ADCC, mAbs act on their target by causing signal perturbation and complement activation. Cetuximab is an EGFR targeting mAb use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32bde38b4095915133a51af1c07b3eef
https://doi.org/10.1158/1538-7445.am2017-633
https://doi.org/10.1158/1538-7445.am2017-633
Autor:
Sandra A. Jablonski, Dalal AlDeghaither, Joseph C. Murray, Louis M. Weiner, Elana J. Fertig, Shaojun Tang, Sarah Martinez Roth
Publikováno v:
Journal of Clinical Oncology. 35:130-130
130 Background: EGFR overexpression & amplification is seen in many types of cancer. Cetuximab is an EGFR targeting monoclonal antibody that acts by signal perturbation, complement activation & inducing antibody dependent cellular cytotoxicity(ADCC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77e3610523b74dda21a7915ea8e68d17
https://doi.org/10.1200/jco.2017.35.7_suppl.130
https://doi.org/10.1200/jco.2017.35.7_suppl.130