Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sarah Mallay"'
Publikováno v:
Redox Report, Vol 25, Iss 1, Pp 87-94 (2020)
Our group recently documented that male mice containing a deletion for one copy of the glutaredoxin-2 (Grx2) gene were completely protected from developing diet-induced obesity (DIO). Objectives: Here, we conducted a similar investigation but with fe
Externí odkaz:
https://doaj.org/article/868551d49b6f4971b2571c0751a43bd8
Publikováno v:
Antioxidants, Vol 8, Iss 8, p 245 (2019)
Our group recently published a study demonstrating that deleting the gene encoding the matrix thiol oxidoreductase, glutaredoxin-2 (GRX2), alters the bioenergetics of mitochondria isolated from male C57BL/6N mice. Here, we conducted a similar study,
Externí odkaz:
https://doaj.org/article/4bf2473795564854810e825d30c2ce1c
Publikováno v:
Canadian Journal of Respiratory, Critical Care, and Sleep Medicine. 4:133-141
BACKGROUND: Severe asthma patients require high-dose inhaled corticosteroids (ICS) plus a second controller medication to control their disease or remain inadequately controlled despite this. Benra...
Publikováno v:
Canadian Journal of Respiratory, Critical Care, and Sleep Medicine. 3:106-111
BACKGROUND: Benralizumab is a monoclonal antibody to the alpha subunit of the IL-5 receptor used in the management of severe, eosinophilic asthma. Although Benralizumab has been shown to si...
Autor:
Catherine Oldford, Ryan J. Mailloux, Sarah Emily Dixon, Sarah Mallay, Ibrahim Dogar, Robert Gill, Adrian Young
Publikováno v:
Free radical biologymedicine. 146
Here, we demonstrate that the upregulation of catalase is required to compensate for the loss of nicotinamide nucleotide transhydrogenase (NNT) to maintain hydrogen peroxide (H2O2) steady-state levels in C57BL/6J liver mitochondria. Our investigation
Publikováno v:
Antioxidants
Volume 8
Issue 8
Antioxidants, Vol 8, Iss 8, p 245 (2019)
Volume 8
Issue 8
Antioxidants, Vol 8, Iss 8, p 245 (2019)
Our group recently published a study demonstrating that deleting the gene encoding the matrix thiol oxidoreductase, glutaredoxin-2 (GRX2), alters the bioenergetics of mitochondria isolated from male C57BL/6N mice. Here, we conducted a similar study,