Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sarah Maines-Bandiera"'
Autor:
Kasmintan A Schrader, Bella Gorbatcheva, Janine Senz, Alireza Heravi-Moussavi, Nataliya Melnyk, Clara Salamanca, Sarah Maines-Bandiera, Susanna L Cooke, Peter Leung, James D Brenton, C Blake Gilks, John Monahan, David G Huntsman
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7988 (2009)
A somatic mutation in the FOXL2 gene is reported to be present in almost all (97%; 86/89) morphologically defined, adult-type, granulosa-cell tumors (A-GCTs). This FOXL2 c.402C>G mutation changes a highly conserved cysteine residue to a tryptophan (p
Externí odkaz:
https://doaj.org/article/9dac698e2e71473caaba9fcb45cdb965
Autor:
Genny Trigo-Gonzalez, Martin M. Matzuk, Janine Senz, Gregg B. Morin, Winnie Yang, Jaeyeon Kim, Yemin Wang, Michael S. Anglesio, Sarah Maines-Bandiera, David G. Huntsman, Jiamin Chen, S.-W. Grace Cheng, Jamie Rosner, Melissa K McMonechy
Publikováno v:
The Journal of Pathology. 237:215-225
DICER1 plays a critical role in microRNA (miRNA) biogenesis. Recurrent somatic 'hotspot' mutations at the four metal-binding sites within the RNase IIIb domain of DICER1 were identified in ovarian sex cord-stromal tumours and have since been describe
Autor:
Clara Salamanca, Yi Kan Wang, Janine Senz, Alireza Heravi-Moussavi, Adrian Wan, Gregg B. Morin, Winnie Yang, David G. Huntsman, Sarah Maines-Bandiera, Michael S. Anglesio
Publikováno v:
The Journal of Pathology. 229:400-409
Our group recently described recurrent somatic mutations of the miRNA processing gene DICER1 in non-epithelial ovarian cancer. Mutations appeared to be clustered around each of four critical metal-binding residues in the RNase IIIB domain of DICER1.
Autor:
Laurie L. Molday, Peter C.K. Leung, Sarah Maines-Bandiera, Robert S. Molday, Blake Gilks, Michelle M.M. Woo, Theresa Hii, Nelly Auersperg, Marilyn J. Borugian
Publikováno v:
International Journal of Gynecological Cancer. 20:16-22
Introduction: Epithelial ovarian carcinomas are highly lethal because most are detected at late stages. A previous immunohistochemical analysis showed that oviductal glycoprotein 1 (OVGP1), a secretory product of the oviductal epithelium under estrog
Autor:
Clara Tan, Nelly Auersperg, Colleen Wu, Sarah Maines-Bandiera, Jane Cipollone, Aly Karsan, Calvin D. Roskelley
Publikováno v:
Differentiation. 76:193-205
E-cadherin expression is unusually regulated in epithelial ovarian carcinoma. It is not expressed in poorly cohesive ovarian surface epithelial (OSE) target cells, but is expressed in cohesive pre-malignant lesions and in highly cohesive, well-differ
Autor:
Yu Sun, Yinghui Guan, C. Collins, Peter C.K. Leung, Sarah Maines-Bandiera, Guiqing Huang, Peixiang Li, Joe W. Gray, Wen Lin Kuo, Nelly Auersperg, Mark Hills
Publikováno v:
International Journal of Cancer. 120:1863-1873
The transcription factor ZNF217 is often amplified in ovarian cancer, but its role in neoplastic progression is unknown. We introduced ZNF217-HA by adenoviral and retroviral infection into normal human ovarian surface epithelial cells (OSE), i.e., th
Autor:
Jeffrey M. Trent, Pilar Ramos, Sarah Maines-Bandiera, David G. Huntsman, Anthony N. Karnezis, Yemin Wang, Bernard E. Weissman, Nancy Dos Santos, Christine Chow, Shary Chen
Publikováno v:
Clinical Cancer Research. 23:AP32-AP32
PURPOSE: SCCOHT is a rare, poorly differentiated and very deadly ovarian tumor that mainly affects young women with the median age in twenties. Recently, we and others have discovered that the genome of SCCOHT was minimally disturbed compared to comm
Autor:
Jiamin, Chen, Yemin, Wang, Melissa K, McMonechy, Michael S, Anglesio, Winnie, Yang, Janine, Senz, Sarah, Maines-Bandiera, Jamie, Rosner, Genny, Trigo-Gonzalez, S W, Grace Cheng, Jaeyeon, Kim, Martin M, Matzuk, Gregg B, Morin, David G, Huntsman
Publikováno v:
The Journal of pathology. 237(2)
DICER1 plays a critical role in microRNA (miRNA) biogenesis. Recurrent somatic 'hotspot' mutations at the four metal-binding sites within the RNase IIIb domain of DICER1 were identified in ovarian sex cord-stromal tumours and have since been describe
Publikováno v:
International Journal of Cancer. 85:430-437
Epithelial ovarian carcinomas are thought to originate in the ovarian surface epithelium (OSE), i.e., the mesothelium covering the ovary, but experimental evidence for this origin has been lacking. Contrary to most epithelia, where neoplastic progres
Autor:
Nelly Auersperg, Keith R. Johnson, Calvin D. Roskelley, Barry P. Rosen, Peter C.K. Leung, Sarah Maines-Bandiera, Margaret J. Wheelock, Alice S.T. Wong
Publikováno v:
International Journal of Cancer. 81:180-188
Epithelial ovarian carcinomas arise in a simple mesothelium (ovarian surface epithelium, OSE) but exhibit properties of oviductal and endometrial epithelia. Thus, during malignant progression, their differentiation proceeds from simple to complex, in