Výsledky vyhledávání - "Sarah M. Sterling"

Akademický článek

Practices for running a research-oriented shared cryo-EM facility

Autor: Richard M. Walsh, Megan L. Mayer, Christopher H. Sun, Shaun Rawson, Remya Nair, Sarah M. Sterling, Zongli Li

Publikováno v: Frontiers in Molecular Biosciences, Vol 9 (2022)

The Harvard Cryo-Electron Microscopy Center for Structural Biology, which was formed as a consortium between Harvard Medical School, Boston Children’s Hospital, Dana-Farber Cancer Institute, and Massachusetts General Hospital, serves both academic

Externí odkaz: https://doaj.org/article/d9a2330689554521b1c605072c89289c

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Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants

Autor: Haisun Zhu, Christy L. Lavine, Wei Yang, Pei Tong, Avneesh Gautam, Sarah M. Sterling, Hanqin Peng, Krishna Anand, Shaun Rawson, Shen Lu, Jianming Lu, Tianshu Xiao, Yongfei Cai, Michael S. Seaman, Bing Chen, Jun Zhang, Duane R. Wesemann, Richard M. Walsh, Sophia Rits-Volloch

Publikováno v: bioRxiv

SARS-CoV-2 from alpha to epsilon As battles to contain the COVID-19 pandemic continue, attention is focused on emerging variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that have been deemed variants of concern becau

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172e4deeaf26e6441edd55554dc8400c
https://doi.org/10.1101/2021.04.13.439709

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Structural impact on SARS-CoV-2 spike protein by D614G substitution

Autor: Sarah M. Sterling, Tianshu Xiao, Hanqin Peng, Yongfei Cai, Bing Chen, Jun Zhang, Jianming Lu, Piotr Sliz, Richard M. Walsh, Sophia Rits-Volloch

Publikováno v: bioRxiv

Substitution for aspartic acid by glycine at position 614 in the spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the ongoing pandemic, appears to facilitate rapid viral spread. The G614 varian

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db09d1c6195dd190738553c2cac5c011
https://doi.org/10.1101/2020.10.13.337980

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Distinct conformational states of SARS-CoV-2 spike protein

Autor: Richard M. Walsh, Yongfei Cai, Sophia Rits-Volloch, Bing Chen, Jun Zhang, Shaun Rawson, Tianshu Xiao, Sarah M. Sterling, Hanqin Peng

Publikováno v: Science (New York, N.y.)
bioRxiv

The ongoing SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic has created urgent needs for intervention strategies to control the crisis. The spike (S) protein of the virus forms a trimer and catalyzes fusion between viral and tar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8101174852016f1a9aef859ff534ee6e
https://doi.org/10.1101/2020.05.16.099317

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Effects of Bni5 Binding on Septin Filament Organization

Autor: Sarah M. Sterling, Elizabeth A. Booth, Dustin Dovala, Eva Nogales, Jeremy Thorner

Publikováno v: Journal of molecular biology, vol 428, iss 24 Pt B
Booth, EA; Sterling, SM; Dovala, D; Nogales, E; & Thorner, J. (2016). Effects of Bni5 Binding on Septin Filament Organization. Journal of Molecular Biology, 428(24), 4962-4980. doi: 10.1016/j.jmb.2016.10.024. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/80x3w0tz

© 2016 The Authors Septins are a protein family found in all eukaryotes (except higher plants) that have roles in membrane remodeling and formation of diffusion barriers and as a scaffold to recruit other proteins. In budding yeast, proper execution

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb14c3eb193d11c596cdfaff39ae9858
https://doi.org/10.1016/j.jmb.2016.10.024

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Phospholipid Diffusion Coefficients of Cushioned Model Membranes Determined via Z-Scan Fluorescence Correlation Spectroscopy

Autor: Jorg Fick, Michael Mason, David J. Neivandt, Igor Prudovsky, Edward S. Allgeyer, Sarah M. Sterling

Publikováno v: Langmuir. 29:7966-7974

Model cellular membranes enable the study of biological processes in a controlled environment and reduce the traditional challenges associated with live or fixed cell studies. However, model membrane systems based on the air/water or oil/solution int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2442eec98d9e5ab39dbe88cbe5dfa2
https://doi.org/10.1021/la400768s

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Protein-Phospholipid Interactions in Nonclassical Protein Secretion: Problem and Methods of Study

Autor: David J. Neivandt, Thallapuranam Krishnaswamy Suresh Kumar, Igor Prudovsky, Sarah M. Sterling

Publikováno v: International Journal of Molecular Sciences, Vol 14, Iss 2, Pp 3734-3772 (2013)
International Journal of Molecular Sciences

Extracellular proteins devoid of signal peptides use nonclassical secretion mechanisms for their export. These mechanisms are independent of the endoplasmic reticulum and Golgi. Some nonclassically released proteins, particularly fibroblast growth fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1804e8778bb2bc5b21905fcf2bfe1610
https://doi.org/10.3390/ijms14023734

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Coordinate action of distinct sequence elements localizes checkpoint kinase Hsl1 to the septin collar at the bud neck in Saccharomyces cerevisiae

Autor: Aspram Sargsyan, Elizabeth N. Liao, Gregory C. Finnigan, Angela Duvalyan, Jeremy Thorner, Sarah M. Sterling, Galo Garcia, Eva Nogales

Publikováno v: Molecular Biology of the Cell

A long-standing conundrum is resolved about the underlying sequence determinants and molecular mechanism responsible for the recruitment of the protein kinase Hsl1 (an indispensable component of the so-called “morphogenesis checkpoint”) exclusive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13803cb45ee1339ffef7c337b98bb9b0
https://pubmed.ncbi.nlm.nih.gov/27193302

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Comparison Actin- and Glass-Supported Phospholipid Bilayer Diffusion Coefficients

Autor: Sharon Ashworth, Ryan Dawes, David J. Neivandt, Edward S. Allgeyer, Sarah M. Sterling

The formation of biomimetic lipid membranes has the potential to provide insights into cellular lipid membrane dynamics. The construction of such membranes necessitates not only the utilization of appropriate lipids, but also physiologically relevant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df36c9bf2add4e99f81d6bc90c443e6
https://europepmc.org/articles/PMC4407249/

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Combining total internal reflection sum frequency spectroscopy spectral imaging and confocal fluorescence microscopy

Autor: Mudalige S. Gunewardene, Michael Mason, Samuel T. Hess, Edward S. Allgeyer, David J. Neivandt, Sarah M. Sterling

Publikováno v: Langmuir : the ACS journal of surfaces and colloids. 31(3)

Understanding surface and interfacial lateral organization in material and biological systems is critical in nearly every field of science. The continued development of tools and techniques viable for elucidation of interfacial and surface informatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6395e39bfd5024643c3e69228d1fdd16
https://pubmed.ncbi.nlm.nih.gov/25506739

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