Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sarah M. Scarry"'
Autor:
Ben Gold, Jun Zhang, Landys Lopez Quezada, Julia Roberts, Yan Ling, Madeleine Wood, Wasima Shinwari, Laurent Goullieux, Christine Roubert, Laurent Fraisse, Eric Bacqué, Sophie Lagrange, Bruno Filoche-Rommé, Michal Vieth, Philip A. Hipskind, Louis N. Jungheim, Jeffrey Aubé, Sarah M. Scarry, Stacey L. McDonald, Kelin Li, Andrew Perkowski, Quyen Nguyen, Véronique Dartois, Matthew Zimmerman, David B. Olsen, Katherine Young, Shilah Bonnett, Douglas Joerss, Tanya Parish, Helena I. Boshoff, Kriti Arora, Clifton E. Barry, Laura Guijarro, Sara Anca, Joaquín Rullas, Beatriz Rodríguez-Salguero, Maria S. Martínez-Martínez, Esther Porras-De Francisco, Monica Cacho, David Barros-Aguirre, Paul Smith, Steven J. Berthel, Carl Nathan, Robert H. Bates
Publikováno v:
ACS Infectious Diseases. 8:557-573
Rising antimicrobial resistance challenges our ability to combat bacterial infections. The problem is acute for tuberculosis (TB), the leading cause of death from infection before COVID-19. Here, we developed a framework for multiple pharmaceutical c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10fbb240736098b21d77522307cf2134
https://doi.org/10.1021/acsinfecdis.1c00570
https://doi.org/10.1021/acsinfecdis.1c00570
Autor:
Samantha Ottavi, Sarah M. Scarry, John Mosior, Yan Ling, Julia Roberts, Amrita Singh, David Zhang, Laurent Goullieux, Christine Roubert, Eric Bacqué, H. Rachel Lagiakos, Jeremie Vendome, Francesca Moraca, Kelin Li, Andrew J. Perkowski, Remya Ramesh, Matthew M. Bowler, William Tracy, Victoria A. Feher, James C. Sacchettini, Ben S. Gold, Carl F. Nathan, Jeffrey Aubé
Publikováno v:
Journal of Medicinal Chemistry. 65:1996-2022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13bb9e5143b62526d09858cde7842507
https://doi.org/10.1021/acs.jmedchem.1c01565
https://doi.org/10.1021/acs.jmedchem.1c01565
Autor:
Ben, Gold, Jun, Zhang, Landys Lopez, Quezada, Julia, Roberts, Yan, Ling, Madeleine, Wood, Wasima, Shinwari, Laurent, Goullieux, Christine, Roubert, Laurent, Fraisse, Eric, Bacqué, Sophie, Lagrange, Bruno, Filoche-Rommé, Michal, Vieth, Philip A, Hipskind, Louis N, Jungheim, Jeffrey, Aubé, Sarah M, Scarry, Stacey L, McDonald, Kelin, Li, Andrew, Perkowski, Quyen, Nguyen, Véronique, Dartois, Matthew, Zimmerman, David B, Olsen, Katherine, Young, Shilah, Bonnett, Douglas, Joerss, Tanya, Parish, Helena I, Boshoff, Kriti, Arora, Clifton E, Barry, Laura, Guijarro, Sara, Anca, Joaquín, Rullas, Beatriz, Rodríguez-Salguero, Maria S, Martínez-Martínez, Esther, Porras-De Francisco, Monica, Cacho, David, Barros-Aguirre, Paul, Smith, Steven J, Berthel, Carl, Nathan, Robert H, Bates
Publikováno v:
ACS infectious diseases. 8(3)
Rising antimicrobial resistance challenges our ability to combat bacterial infections. The problem is acute for tuberculosis (TB), the leading cause of death from infection before COVID-19. Here, we developed a framework for multiple pharmaceutical c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::845c19ee1302d9cba5efc30dfaea239a
https://pubmed.ncbi.nlm.nih.gov/35192346
https://pubmed.ncbi.nlm.nih.gov/35192346
Autor:
Samantha, Ottavi, Sarah M, Scarry, John, Mosior, Yan, Ling, Julia, Roberts, Amrita, Singh, David, Zhang, Laurent, Goullieux, Christine, Roubert, Eric, Bacqué, H Rachel, Lagiakos, Jeremie, Vendome, Francesca, Moraca, Kelin, Li, Andrew J, Perkowski, Remya, Ramesh, Matthew M, Bowler, William, Tracy, Victoria A, Feher, James C, Sacchettini, Ben S, Gold, Carl F, Nathan, Jeffrey, Aubé
Publikováno v:
Journal of medicinal chemistry. 65(3)
A newly validated target for tuberculosis treatment is phosphopantetheinyl transferase, an essential enzyme that plays a critical role in the biosynthesis of cellular lipids and virulence factors in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d38a0e7a30c6fe08d91f48dccb443944
https://pubmed.ncbi.nlm.nih.gov/35044775
https://pubmed.ncbi.nlm.nih.gov/35044775
Autor:
Yan Ling, Landys Lopez Quezada, Tigran M. Abramyan, Sarah M. Scarry, Selin Somersan Karakaya, Kohta Saito, Drew J. Cesta, Jeffrey Aubé, David T Zhang, Julia Roberts, Prisca Elis Javidnia, Dmitri Kireev, Ben Gold
Publikováno v:
Asian Journal of Organic Chemistry. 8:1053-1057
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c88cb1dc3e0d1ae58e8d44f4353a472
https://doi.org/10.1002/ajoc.201900058
https://doi.org/10.1002/ajoc.201900058
Autor:
Vladimir V. Popik, Xiaofen Ma, Zhanhong Wu, Zibo Li, Hui Wang, Mengzhe Wang, Christopher D. McNitt, Sarah M. Scarry
Publikováno v:
Chemical Communications. 54:7810-7813
Here we report the 18F labeling of a prostate specific membrane antigen (PSMA) ligand via a strain promoted oxa-dibenzocyclooctyne (ODIBO)- or bicyclo[6.1.0]nonyne (BCN)-azide reaction. Although ODIBO reacts with azide 20 fold faster than BCN, in viv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbfcd0f926a8d37fd95ad9c2766124ce
https://doi.org/10.1039/c8cc03999b
https://doi.org/10.1039/c8cc03999b
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3372efafc59c6d3c5b8e5837306e128e
https://doi.org/10.1096/fasebj.2019.33.1_supplement.503.11
https://doi.org/10.1096/fasebj.2019.33.1_supplement.503.11
Autor:
Jeffrey Aubé, Curtis A. Engelhart, Elaine Ballinger, Kyu Y. Rhee, Allison Fay, Guangbin Yang, Laurent Fraisse, Kristin Burns-Huang, Jennifer A McConnell, Dirk Schnappinger, Isabelle Le Blanc, Cedric Couturier, Julien Vaubourgeix, Roxanne Morris, James C. Sacchettini, Carl Nathan, Thomas R. Ioerger, Laurent Goullieux, Sarah M. Scarry, Stéphanie Sans, Sophie Lagrange, Eric Bacqué, Ben Gold, Travis Hartman, John W. Mosior, Kathrine McAulay, Christine Roubert, Ouathek Ouerfelli
INTRODUCTION Mycobacterium tuberculosis (Mtb) is the leading global cause of lethal infection in humans and accounts for the largest number of drug-resistant infections by a single bacterial pathogen. Resistance is particularly high against the most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e0031c80d50796d0a46a971a13d8ef
Publikováno v:
Molecular Cancer Research. 18:IA04-IA04
RAS is the most frequently activated oncoprotein in human cancer. Mutations in KRAS are prevalent in pancreatic, colon, and lung cancer. Despite the need for anti-RAS therapies, there are no clinically successful targeted therapies for RAS. We will p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f29d0a25de358b5f8ec752f50c94ac9f
https://doi.org/10.1158/1557-3125.ras18-ia04
https://doi.org/10.1158/1557-3125.ras18-ia04
Publikováno v:
Science signaling. 11(542)
Biased agonists of G protein–coupled receptors may present a means to refine receptor signaling in a way that separates side effects from therapeutic properties. Several studies have shown that agonists that activate the κ-opioid receptor (KOR) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d93f72a371e22eff3ed7587167e9c9
https://pubmed.ncbi.nlm.nih.gov/30087177
https://pubmed.ncbi.nlm.nih.gov/30087177