Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sarah M. Engle"'
Autor:
Jonathan T. Sims, Josh Poorbaugh, Ching-Yun Chang, Timothy R. Holzer, Lin Zhang, Sarah M. Engle, Stephanie Beasley, Thompson N. Doman, Lynn Naughton, Richard E. Higgs, Nicole Kallewaard, Robert J. Benschop
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background A thorough understanding of a patient’s inflammatory response to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection is crucial to discerning the associated, underlying immunological processes and to the selec
Externí odkaz:
https://doaj.org/article/bdd024c53d764522a92238a2eb84f962
Autor:
Varsha Parthasarathy, Karen Cravero, Junwen Deng, Zhe Sun, Sarah M. Engle, Autum N. Auxier, Nathan Hahn, Jonathan T. Sims, Angela J. Okragly, Martin P. Alphonse, Shawn G. Kwatra
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
ImportancePrurigo nodularis (PN) is a chronic heterogeneous inflammatory skin disease.ObjectiveTo elucidate which components of type 2 inflammation are dysregulated systemically in PN.DesignWhole blood was obtained from PN patients with uncontrolled
Externí odkaz:
https://doaj.org/article/5555746fa38d4b13b12e24ca57522990
Autor:
Sarah M. Engle, Justin J. Crowder, Sheldon G. Watts, Christopher J. Indovina, Samuel Z. Coffey, Eric M. Rubenstein
Publikováno v:
PeerJ, Vol 5, p e3728 (2017)
Conserved homologues of the Hrd1 ubiquitin ligase target for degradation proteins that persistently or aberrantly engage the endoplasmic reticulum translocon, including mammalian apolipoprotein B (apoB; the major protein component of low-density lipo
Externí odkaz:
https://doaj.org/article/0fbaeb96e4674b609866b23971a649aa
Autor:
Varsha Parthasarathy, Karen Cravero, Lillian Xu, Junwen Deng, Zhe Sun, Sarah M. Engle, Jonathan T. Sims, Angela J. Okragly, Shawn G. Kwatra
Publikováno v:
Journal of the American Academy of Dermatology. 88:1101-1109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6149264e37a9528f703b50b96ff9e60b
https://doi.org/10.1016/j.jaad.2023.01.042
https://doi.org/10.1016/j.jaad.2023.01.042
Autor:
Samantha M. Turk, Christopher J. Indovina, Danielle L. Overton, Avery M. Runnebohm, Cade J. Orchard, Ellen M. Doss, Kyle A. Richards, Courtney Broshar Irelan, Mahmoud M. Daraghmi, Connor G. Bailey, Jacob M. Miller, Julia M. Niekamp, Samantha K. Gosser, Mary E. Tragesser-Tiña, Kieran P. Claypool, Sarah M. Engle, Bryce W. Buchanan, Kelsey A. Woodruff, James B. Olesen, Philip J. Smaldino, Eric M. Rubenstein
The relationship between lipid homeostasis and protein homeostasis (proteostasis) is complex and remains incompletely understood. We conducted a screen for genes required for efficient degradation ofDeg1-Sec62, a model aberrant translocon-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe8ef0bf08f1938422e157064af703a0
https://doi.org/10.1101/2022.12.09.519544
https://doi.org/10.1101/2022.12.09.519544
Autor:
Eric L. Simpson, Emma Guttman-Yassky, Yushi Liu, Ching Yun Chang, Sean E. Sissons, Jonathan I. Silverberg, Richard E. Higgs, Seth Forman, Jonathan Janes, Jonathan T. Sims, George H. Rodgers, Stephanie C. Colvin, Sarah M. Engle
Publikováno v:
Experimental Dermatology
Background Atopic dermatitis (AD) is a heterogeneous systemic inflammatory skin disease associated with dysregulated immune responses, barrier dysfunction, and activated sensory nerves. Objective To characterize circulating inflammatory profiles and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f92de190a7eff1fcd12f4cae9fb2830b
http://europepmc.org/articles/PMC8596730
http://europepmc.org/articles/PMC8596730
Autor:
Brian J. Nickoloff, Silvia Ottaviani, Jonathan T. Sims, Nicoletta Bivi, Richard E. Higgs, Ajay Nirula, Venkatesh Krishnan, George H. Rodgers, Giacomo Casalini, Robert J. Benschop, Anabela Cardoso, Justin Stebbing, Mario Corbellino, Sarah M. Engle, Ching Yun Chang, Robert J. Konrad, Stephanie de Bono
Publikováno v:
The Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology
Background Physicians treating COVID-19 patients increasingly believe that the hyperinflammatory acute stage of COVID-19 results in a cytokine storm. The circulating biomarkers seen across the spectrum of COVID-19 have not been characterized compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09fd77bcd0ea3c8be3c284be2af4e39
https://doi.org/10.1016/j.jaci.2020.08.031
https://doi.org/10.1016/j.jaci.2020.08.031
Autor:
Jonathan T. Sims, Josh Poorbaugh, Ching-Yun Chang, Timothy R. Holzer, Lin Zhang, Sarah M. Engle, Stephanie Beasley, Thompson N. Doman, Lynn Naughton, Richard E. Higgs, Nicole Kallewaard, Robert J. Benschop
Publikováno v:
Journal of translational medicine. 20(1)
Background A thorough understanding of a patient’s inflammatory response to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection is crucial to discerning the associated, underlying immunological processes and to the selection and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596fe31133fce39ed719a290da53b43b
https://pubmed.ncbi.nlm.nih.gov/35303909
https://pubmed.ncbi.nlm.nih.gov/35303909
Autor:
Rob Tepper, Allyson Satterwhite, Jochen Schmitz, Jonathan T. Sims, Tristan Hayes, Mark H. Kaplan, Kim Robling, Benjamin J. Ulrich, Sean E. Sissons, Sarah M. Engle, Ching-Yun Chang
Background: The pathogenesis of atopic dermatitis (AD) results from complex interactions between environmental factors, barrier defects, and immune dysregulation resulting in systemic inflammation. Therefore, we sought to characterize circulating inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee54da4d23aba8142e2beea98045af2
https://doi.org/10.22541/au.160707698.84878802/v1
https://doi.org/10.22541/au.160707698.84878802/v1
Autor:
Samuel Z. Coffey, Sarah M. Engle, Justin J. Crowder, Sheldon G. Watts, Christopher J. Indovina, Eric M. Rubenstein
Publikováno v:
PeerJ, Vol 5, p e3728 (2017)
PeerJ
PeerJ
Conserved homologues of the Hrd1 ubiquitin ligase target for degradation proteins that persistently or aberrantly engage the endoplasmic reticulum translocon, including mammalian apolipoprotein B (apoB; the major protein component of low-density lipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5e61c4058bea6f3988ebab8ef8f7896
https://peerj.com/articles/3728.pdf
https://peerj.com/articles/3728.pdf