Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sarah M. Eck"'
Publikováno v:
Molecular Cancer Research. 7:1033-1044
The complex molecular communications that occur between neoplastic and stromal cells within the tumor microenvironment play an integral role in breast cancer pathogenesis. Carcinoma-associated fibroblasts (CAF) produce tumor-enhancing factors and hav
Publikováno v:
Breast Cancer Research and Treatment. 116:79-90
Matrix metalloproteinase-1 (MMP-1) is critical for mediating breast cancer metastasis to bone. We investigated the role of MMP-1 in breast cancer invasion of soft tissues and bone using human MDA MB-231 breast cancer cells stably transfected with shR
Publikováno v:
Osteoarthritis and Cartilage. 15(4):431-441
Interleukin-1beta (IL-1beta) stimulates collagenase-1 (Matrix Metalloproteinase-1 (MMP-1)) expression in articular chondrocytes, leading to cleavage of type II collagen and irreversible cartilage degradation. The nuclear factor-kappa B (NF-kappaB) pa
Autor:
Jessica S. Blackburn, Peter S Burrage, Sarah M. Eck, Constance E. Brinckerhoff, Adam C. Schmucker
Similarities in the pathologies of autoimmune diseases and cancer have been noted for at least 30 years. Inflammatory cytokines and growth factors mediate cell proliferation, and proteinases, especially the collagenase, Matrix Metalloproteinase-1 (MM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4eb6fc258034713e3b06edbcdb24915
https://europepmc.org/articles/PMC2783549/
https://europepmc.org/articles/PMC2783549/