Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Sarah M. Cheal"'
Publikováno v:
Journal of Nuclear Medicine. 63:1302-1315
Pretargeted radioimmunodiagnosis and radioimmunotherapy aim to efficiently combine antitumor antibodies and medicinal radioisotopes for high-contrast imaging and high-therapeutic-index (TI) tumor targeting, respectively. As opposed to conventional ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f567b2edd8c8f708387c5c049b6d45
https://doi.org/10.2967/jnumed.121.262186
https://doi.org/10.2967/jnumed.121.262186
Autor:
Sarah M. Cheal, Steven M. Larson, Nai Kong V. Cheung, Neeta Pandit-Taskar, Achim Jungbluth, Andrea Cercek, Garrett M. Nash, Sébastien Monette, Pat B. Zanzonico, Brian H. Santich, Hong-fen Guo, Hong Xu, Mitesh Patel, Daniela Burnes Vargas, Blesida Punzalan, Edward K. Fung, Darren R. Veach, Sebastian K. Chung, Meghan M. Bell, Christopher S. Chandler
Peritoneal carcinomatosis (PC) is considered incurable, and more effective therapies are needed. Herein we test the hypothesis that GPA33-directed intracompartmental pretargeted radioimmunotherapy (PRIT) can cure colorectal peritoneal carcinomatosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acef59b9b8016bb1ef603c3ce50fbe38
https://doi.org/10.1158/1535-7163.c.6543270.v1
https://doi.org/10.1158/1535-7163.c.6543270.v1
Autor:
Sarah M. Cheal, Steven M. Larson, Nai Kong V. Cheung, Neeta Pandit-Taskar, Achim Jungbluth, Andrea Cercek, Garrett M. Nash, Sébastien Monette, Pat B. Zanzonico, Brian H. Santich, Hong-fen Guo, Hong Xu, Mitesh Patel, Daniela Burnes Vargas, Blesida Punzalan, Edward K. Fung, Darren R. Veach, Sebastian K. Chung, Meghan M. Bell, Christopher S. Chandler
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4552114e96bd1d8d447a47494ca35371
https://doi.org/10.1158/1535-7163.22522074
https://doi.org/10.1158/1535-7163.22522074
Bispecific antibodies (BsAb) have proven to be useful targeting vectors for pretargeted radioimmunotherapy (PRIT). We sought to overcome key PRIT limitations such as high renal radiation exposure and immunogenicity (e.g., of streptavidin–antibody f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::663f162f0f480009d3a3366e306760d8
https://doi.org/10.1158/1535-7163.c.6536547.v1
https://doi.org/10.1158/1535-7163.c.6536547.v1
Supplementary Figure S1. Modeling comparison of two different therapy regimens. Supplementary Figure S2. Positron-emission tomography imaging data for I-124 labeled bispecific antibody in tumor-bearing mice. Supplementary Figure S3. Biodistribution d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fa32b74b1154b31f255371a759fe36
https://doi.org/10.1158/1535-7163.22500711.v1
https://doi.org/10.1158/1535-7163.22500711.v1
Autor:
Nai K. Cheung, Steven M. Larson, Charles M. Rudin, Adam O. Michel, Sebastien Monette, Pat B. Zanzonico, Hong-Fen Guo, Aiza A. Malik, Daniela Burnes Vargas, Mitesh Patel, Edward K. Fung, Darren R. Veach, Guangbin Yang, Ouathek Ouerfelli, Michael R. McDevitt, Mahiuddin Ahmed, Sarah M. Cheal, Brian H. Santich
Summary of immunogenicity experiment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66e998a48dfc37d4b7f720c68d19b49
https://doi.org/10.1158/1078-0432.22479494
https://doi.org/10.1158/1078-0432.22479494
Autor:
Nai K. Cheung, Steven M. Larson, Charles M. Rudin, Adam O. Michel, Sebastien Monette, Pat B. Zanzonico, Hong-Fen Guo, Aiza A. Malik, Daniela Burnes Vargas, Mitesh Patel, Edward K. Fung, Darren R. Veach, Guangbin Yang, Ouathek Ouerfelli, Michael R. McDevitt, Mahiuddin Ahmed, Sarah M. Cheal, Brian H. Santich
2-step SADA-PRIT imaging by PET/CT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227c28b24bf83bfd1f7bde02d3209963
https://doi.org/10.1158/1078-0432.22479479.v1
https://doi.org/10.1158/1078-0432.22479479.v1
Autor:
Michael J. Morris, Steven M. Larson, Howard I. Scher, Neil H. Bander, Wolfgang A. Weber, Victor E. Reuter, Jason S. Lewis, Joseph R. Osborne, Jarett L. Feldman, Scott T. Tagawa, David M. Nanus, Massimo Loda, Glenn Heller, Mithat Gönen, Stephen B. Solomon, Alex Mak Fung, Danny F. Martinez, Jorge A. Carrasquillo, Robert A. Lefkowitz, Volkan Beylergil, Sarah M. Cheal, Serge K. Lyashchenko, Jeremy C. Durack, Joseph A. O'Donoghue, Neeta Pandit-Taskar
Supplementary Table S1. Patient demographics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7911cde2c14dc035eb71eb5f63c968
https://doi.org/10.1158/1078-0432.22461827
https://doi.org/10.1158/1078-0432.22461827
Autor:
Nai K. Cheung, Steven M. Larson, Charles M. Rudin, Adam O. Michel, Sebastien Monette, Pat B. Zanzonico, Hong-Fen Guo, Aiza A. Malik, Daniela Burnes Vargas, Mitesh Patel, Edward K. Fung, Darren R. Veach, Guangbin Yang, Ouathek Ouerfelli, Michael R. McDevitt, Mahiuddin Ahmed, Sarah M. Cheal, Brian H. Santich
2-step IgG-PRIT imaging by PET/CT (no CA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159371a30c8b7589fca7e3bf2b89bf2e
https://doi.org/10.1158/1078-0432.22479473.v1
https://doi.org/10.1158/1078-0432.22479473.v1
Autor:
Michael J. Morris, Steven M. Larson, Howard I. Scher, Neil H. Bander, Wolfgang A. Weber, Victor E. Reuter, Jason S. Lewis, Joseph R. Osborne, Jarett L. Feldman, Scott T. Tagawa, David M. Nanus, Massimo Loda, Glenn Heller, Mithat Gönen, Stephen B. Solomon, Alex Mak Fung, Danny F. Martinez, Jorge A. Carrasquillo, Robert A. Lefkowitz, Volkan Beylergil, Sarah M. Cheal, Serge K. Lyashchenko, Jeremy C. Durack, Joseph A. O'Donoghue, Neeta Pandit-Taskar
Supplementary Figures S1-4. Figure S1. 89Zr-J591 versus bone scan comparison of lesion positivity. Figure S2. Patient with metastatic prostate cancer (PSA of 10.1) with 89Zr-J591+ lesions that were not seen on MDP. Figure S3. Patient with metastatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f83f971b3c5f621002858804f81b812
https://doi.org/10.1158/1078-0432.22461830
https://doi.org/10.1158/1078-0432.22461830