Strain-resolved metagenomic analysis of the gut as a reservoir for bloodstream infection pathogens among premature infants in Singapore

Autor: Sarah M. Heston, Charis Shu En Lim, Chengsi Ong, Mei Chien Chua, Matthew S. Kelly, Kee Thai Yeo

Publikováno v: Gut Pathogens, Vol 15, Iss 1, Pp 1-14 (2023)

Abstract Background Gut dysbiosis contributes to the high risk of bloodstream infection (BSI) among premature infants. Most prior studies of the premature infant gut microbiota were conducted in Western countries and prior to development of current t

Externí odkaz: https://doaj.org/article/50057c07207943d8aabcf30311f8b8e0

The Gut Resistome during Hematopoietic Stem Cell Transplantation in Children

Autor: Sarah M. Heston, Rebecca R. Young, Kirsten Jenkins, Paul L. Martin, Andre Stokhuyzen, Doyle V. Ward, Shakti K. Bhattarai, Vanni Bucci, Mehreen Arshad, Nelson J. Chao, Patrick C. Seed, Matthew S. Kelly

BackgroundChildren undergoing hematopoietic stem cell transplantation (HCT) are at high risk of acquiring antibiotic-resistant bacteria. Few prior studies examined antibiotic resistance genes (ARGs) within the gut metagenomes of children undergoing H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4cee031806df636e00dcc025ad19cea2
https://doi.org/10.1101/2022.07.07.22277185

Risk Factors for CMV Viremia and Treatment-Associated Adverse Events Among Pediatric Hematopoietic Stem Cell Transplant Recipients

Autor: Sarah M Heston, Rebecca R Young, John S Tanaka, Kirsten Jenkins, Richard Vinesett, Frances M Saccoccio, Paul L Martin, Nelson J Chao, Matthew S Kelly

Publikováno v: Open Forum Infectious Diseases

Background Cytomegalovirus (CMV) causes substantial morbidity and mortality after hematopoietic stem cell transplantation (HSCT). There are limited data on risk factors for CMV viremia and the safety of antiviral medications used to treat CMV in chil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a44cc4728332cdbe3100ffb45c7a0c1
https://doi.org/10.1093/ofid/ofab639

#45 Antibiotic Exposure and Risk of Cytomegalovirus Viremia Among Pediatric Hematopoietic Stem Cell Transplant Recipients at a Single Institution

Autor: Sarah M Heston

Publikováno v: Journal of the Pediatric Infectious Diseases Society. 11:S2-S2

Background Cytomegalovirus (CMV) causes substantial morbidity and mortality after hematopoietic stem cell transplantation (HCT), and antibiotic exposure after HCT is increasingly recognized as a risk for negative clinical outcomes. Recent studies ide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30d615e1fcde9a45404b3c235f2d6129
https://doi.org/10.1093/jpids/piac041.006

SARS-CoV-2 Infections Among Children in the Biospecimens from Respiratory Virus-Exposed Kids (BRAVE Kids) Study

Autor: Kirsten Jenkins, Sallie R. Permar, C. Todd DeMarco, M. Anthony Moody, Nicholas A Turner, Hannah M Cunningham, Thomas N. Denny, Carter G Crew, Raul Louzao, Congwen Zhao, Lilianna Suarez, Jhoanna N. Aquino, Christopher W. Woods, Stephanie H Smith, Thaddeus C. Gurley, Jillian H. Hurst, Debra J Lugo, Sarah M Heston, Trevor S Pfeiffer, Javier Rodriguez, William J. Steinbach, Matthew S. Kelly, S. Michelle Griffin, Emmanuel B. Walter, Meghan Price, Nicole A De Naeyer, Alexandre T. Rotta, Coleen K. Cunningham, Shree Bose, Hailey N Chambers, Stuart Carr

Publikováno v: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases
medRxiv
article-version (status) pre
article-version (number) 2

Background Child with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection typically have mild symptoms that do not require medical attention, leaving a gap in our understanding of the spectrum of SARS-CoV-2-related illnesses that t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32813cbe44f31d607c3d9af42f8e2e23
http://europepmc.org/articles/PMC7665428