Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Sarah M, Schumacher"'
Autor:
Venkata Naga Srikanth Garikipati, Suresh Kumar Verma, Zhongjian Cheng, Dongming Liang, May M. Truongcao, Maria Cimini, Yujia Yue, Grace Huang, Chunlin Wang, Cindy Benedict, Yan Tang, Vandana Mallaredy, Jessica Ibetti, Laurel Grisanti, Sarah M. Schumacher, Erhe Gao, Sudarsan Rajan, Jeremy E. Wilusz, David Goukassian, Steven R. Houser, Walter J. Koch, Raj Kishore
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Circular RNAs (circRNAs) are non-coding RNAs generated from pre-mRNAs of coding genes by the splicing machinery whose function in the heart is poorly understood. Here the authors show that AAV-mediated delivery of the circRNA circFndc3b prevents card
Externí odkaz:
https://doaj.org/article/d5d34ad17adb4becbc41b78b8495bb2e
Autor:
Venkata Naga Srikanth Garikipati, Suresh Kumar Verma, Zhongjian Cheng, Dongming Liang, May M. Truongcao, Maria Cimini, Yujia Yue, Grace Huang, Chunlin Wang, Cindy Benedict, Yan Tang, Vandana Mallaredy, Jessica Ibetti, Laurel Grisanti, Sarah M. Schumacher, Erhe Gao, Sudarsan Rajan, Jeremy E. Wilusz, David Goukassian, Steven R. Houser, Walter J. Koch, Raj Kishore
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-2 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/527dfca276e348d2980b5fc41dc6a63c
Autor:
Ama Dedo Okyere, Jianliang Song, Viren Patwa, Rhonda L. Carter, Nitya Enjamuri, Anna Maria Lucchese, Jessica Ibetti, Claudio de Lucia, Sarah M. Schumacher, Walter J. Koch, Joseph Y. Cheung, Jeffrey L. Benovic, Douglas G. Tilley
Publikováno v:
Cardiovascular Drugs and Therapy. 37:245-256
Autor:
Dhanendra Tomar, Zhiwei Dong, Santhanam Shanmughapriya, Diana A. Koch, Toby Thomas, Nicholas E. Hoffman, Shrishiv A. Timbalia, Samuel J. Goldman, Sarah L. Breves, Daniel P. Corbally, Neeharika Nemani, Joseph P. Fairweather, Allison R. Cutri, Xueqian Zhang, Jianliang Song, Fabián Jaña, Jianhe Huang, Carlos Barrero, Joseph E. Rabinowitz, Timothy S. Luongo, Sarah M. Schumacher, Michael E. Rockman, Alexander Dietrich, Salim Merali, Jeffrey Caplan, Peter Stathopulos, Rexford S. Ahima, Joseph Y. Cheung, Steven R. Houser, Walter J. Koch, Vickas Patel, Vishal M. Gohil, John W. Elrod, Sudarsan Rajan, Muniswamy Madesh
Publikováno v:
Cell Reports, Vol 15, Iss 8, Pp 1673-1685 (2016)
Mitochondrial Ca2+ Uniporter (MCU)-dependent mitochondrial Ca2+ uptake is the primary mechanism for increasing matrix Ca2+ in most cell types. However, a limited understanding of the MCU complex assembly impedes the comprehension of the precise mecha
Externí odkaz:
https://doaj.org/article/824669f56e69431d8fcf04ba6cd6b4d4
Autor:
Jessica Pfleger, Kamila Bledzka, Iyad H. Manaserh, Jessica Grondolsky, Sarah M. Schumacher, Erhe Gao, Walter J. Koch, Rajika Roy, J. Kurt Chuprun
Publikováno v:
J Mol Cell Cardiol
G protein-coupled receptor (GPCR) kinase 2 (GRK2) expression and activity are elevated early on in response to several forms of cardiovascular stress and are a hallmark of heart failure. Interestingly, though, in addition to its well-characterized ro
Autor:
Philipp Schlegel, Julia Reinkober, Eric Meinhardt, Henrike Tscheschner, Erhe Gao, Sarah M Schumacher, Ancai Yuan, Johannes Backs, Patrick Most, Thomas Wieland, Walter J Koch, Hugo A Katus, Philip W Raake
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0182110 (2017)
The increase in protein activity and upregulation of G-protein coupled receptor kinase 2 (GRK2) is a hallmark of cardiac stress and heart failure. Inhibition of GRK2 improved cardiac function and survival and diminished cardiac remodeling in various
Externí odkaz:
https://doaj.org/article/73aee9149d9c43f68bd8d68bdc460de0
Autor:
Dennis Lal, Daniel Blankenberg, Marie Gramm, Sarah M Schumacher-Bass, Costin Leu, Jarrod E. Dalton, Eduardo Pérez-Palma
Publikováno v:
Bioinformatics. 37:4285-4287
Summary Literature exploration in PubMed on a large number of biomedical entities (e.g. genes, diseases or experiments) can be time-consuming and challenging, especially when assessing associations between entities. Here, we describe SimText, a user-
Autor:
Amanda E. Paluch, Steven N. Blair, John E. Blundell, Daniel P. O'Connor, Stephanie Burgess, Madison M Kindred, Sarah M. Schumacher, Clemens Drenowatz, Gregory A. Hand, Robin P. Shook
Publikováno v:
Journal of Physical Activity and Health. 17:456-463
Background: The present study examined, among weight-stable overweight or obese adults, the effect of increasing doses of exercise energy expenditure (EEex) on changes in total daily energy expenditure (TDEE), total body energy stores, and body compo
Autor:
Ama Dedo, Okyere, Jianliang, Song, Viren, Patwa, Rhonda L, Carter, Nitya, Enjamuri, Anna Maria, Lucchese, Jessica, Ibetti, Claudio, de Lucia, Sarah M, Schumacher, Walter J, Koch, Joseph Y, Cheung, Jeffrey L, Benovic, Douglas G, Tilley
Publikováno v:
Cardiovascular drugs and therapy.
β-Adrenergic receptors (βAR) are essential targets for the treatment of heart failure (HF); however, chronic use of βAR agonists as positive inotropes to increase contractility in a GWe measured adult mouse cardiomyocyte contractility in response
Autor:
Sarah M. Schumacher, Baljit S. Khakh, Matthias Ollivier, Zhe Qu, Arash Bellafard, Mohitkumar R. Gangwani, Viviana Gradinaru, Peyman Golshani, Giovanni Coppola, Xinzhu Yu, Blanca Diaz-Castro, Jun Nagai
Publikováno v:
Neuron
Summary Astrocytes respond to neurotransmitters and neuromodulators using G-protein-coupled receptors (GPCRs) to mediate physiological responses. Despite their importance, there has been no method to genetically, specifically, and effectively attenua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf9debd44c8d05412da442b0513b55b
https://resolver.caltech.edu/CaltechAUTHORS:20210625-220915439
https://resolver.caltech.edu/CaltechAUTHORS:20210625-220915439