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pro vyhledávání: '"Sarah Leigh-Brown"'
Autor:
Sarah Leigh-Brown, Angela Goncalves, David Thybert, Klara Stefflova, Stephen Watt, Paul Flicek, Alvis Brazma, John C Marioni, Duncan T Odom
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137367 (2015)
Phenotypic differences between species are driven by changes in gene expression and, by extension, by modifications in the regulation of the transcriptome. Investigation of mammalian transcriptome divergence has been restricted to analysis of bulk ge
Externí odkaz:
https://doaj.org/article/d8a1019b5ad84ccbbf80157fe88db89a
Autor:
Paul Flicek, Klara Stefflova, Sarah Leigh-Brown, Alvis Brazma, David Thybert, Angela Goncalves, Duncan T. Odom, Stephen Watt, John C. Marioni
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137367 (2015)
PLoS ONE
PLoS ONE
Phenotypic differences between species are driven by changes in gene expression and, by extension, by modifications in the regulation of the transcriptome. Investigation of mammalian transcriptome divergence has been restricted to analysis of bulk ge
Autor:
David Thybert, John C. Marioni, Alvis Brazma, Klara Stefflova, Paul Flicek, Duncan T. Odom, Angela Goncalves, Ernest Turro, Sarah Leigh-Brown
Publikováno v:
Genome Research; Vol 22
Genome Research
Genome Research
Gene expression levels are thought to diverge primarily via regulatory mutations in trans within species, and in cis between species. To test this hypothesis in mammals we used RNA-sequencing to measure gene expression divergence between C57BL/6J and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e571c4ed6f62dcc8bce45216175b106
https://europepmc.org/articles/PMC3514667/
https://europepmc.org/articles/PMC3514667/
Publikováno v:
Genome Biology
Nuclear transcription factors have been detected in mammalian mitochondria and may directly regulate mitochondrial gene expression. Emerging genomics techniques may overcome outstanding challenges in this field.