Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sarah LeBoeuf"'
Autor:
Ray Pillai, Sarah LeBoeuf, Ali Rashidfarrokhi, Shih Ming Huang, Triantafyllia Karakousi, Anastasia-Maria Zavitsanou, Warren Wu, Volkan Sayin, Robert Wild, Sergei Koralov, Thales Papagiannakopoulos
Publikováno v:
Cancer Research. 83:4904-4904
KEAP1 is mutated in approximately 20% of non-small cell lung cancer (NSCLC) and is associated with poor response rates to checkpoint blockade. Given the therapeutic challenge presented by KEAP1 mutant tumors and the great potential held by immunother
Autor:
Sarah LeBoeuf, Ray Pillai, Shih Ming Huang, Triantafyllia Karakousi, Warren Wu, Volkan Sayin, Robert Wild, Thales Papagiannakopoulos
Publikováno v:
Cancer Research. 82:2174-2174
Treating KRAS mutant lung adenocarcinoma (LUAD) remains a major challenge for clinical oncology. Approximately 20% of KRASmutant LUAD tumors carry loss-of-function mutations in KEAP1, a negative regulator of NRF2, which is the master transcriptional
Autor:
Laurie J. Gay, John Day, Sarah LeBoeuf, Melissa Ritland, Zaverio M. Ruggeri, Wolfram Ruf, Brunhilde H. Felding
Publikováno v:
Cancer Research. 75:B19-B19
Background: The incidence of brain metastasis exceeds that of primary brain tumors tenfold and is most frequently associated with lung cancer, breast cancer and melanoma. Despite a prognosis of only 6-9 months for patients with brain metastases, mech
Autor:
Laurie J. Gay, John Day, Sarah LeBoeuf, Melissa Ritland, Zaverio Ruggeri, Wolfram Ruf, Brunhilde H. Felding
Publikováno v:
Cancer Research. 74:991-991
Background: The incidence of brain metastasis exceeds that of primary brain tumors tenfold and is most frequently associated with lung cancer, breast cancer and melanoma. Despite a prognosis of only 6-9 months for patients with brain metastases, mech