Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Sarah L. Withey"'
Autor:
Dave T. Gerrard, Andrew A. Berry, Rachel E. Jennings, Matthew J. Birket, Peyman Zarrineh, Myles G. Garstang, Sarah L. Withey, Patrick Short, Sandra Jiménez-Gancedo, Panos N. Firbas, Ian Donaldson, Andrew D. Sharrocks, Karen Piper Hanley, Matthew E. Hurles, José Luis Gomez-Skarmeta, Nicoletta Bobola, Neil A. Hanley
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
How the epigenomic landscape linked to transcription regulates human embryonic development is unclear. Here, the authors analyse the dynamics of H3K27Ac, H3K4me3 and H3K27me3 during the period when organs first assemble as a platform for understandin
Externí odkaz:
https://doaj.org/article/a296a0ec6d0e434aa7dff480689080a7
Autor:
Sarah L Withey, Gareth R Willis
Publikováno v:
EBioMedicine, Vol 64, Iss , Pp 103210- (2021)
Externí odkaz:
https://doaj.org/article/ce5a91a09f37460d8a00858d5e44beb4
Autor:
Ahmed Hasbi, Bertha K. Madras, Jack Bergman, Stephen Kohut, Zhicheng Lin, Sarah L. Withey, Susan R. George
Publikováno v:
iScience, Vol 23, Iss 1, Pp - (2020)
Summary: Long-term cannabis users manifest deficits in dopaminergic functions, reflecting Δ9-tetrahydrocannabinol (THC)-induced neuroadaptive dysfunctional dopamine signaling, similar to those observed upon dopamine D1-D2 heteromer activation. The m
Externí odkaz:
https://doaj.org/article/53afb47122854d4e99b4dfbe6d4c3e13
Autor:
Andrew K. Whittaker, Simon Puttick, Sarah L. Withey, Alison L. White, Simon Biggs, Hazel A. Javier, Stephen E. Rose
Publikováno v:
Journal of Colloid and Interface Science. 609:575-583
The efficient encapsulation of small molecule active ingredients has been a challenge for many decades across many commercial applications. Recently, successful attempts to address this issue have included deposition of thin metal shells onto liquid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0ba50b84f0fd8e85f8cf6a4fc995be
https://doi.org/10.1016/j.jcis.2021.11.062
https://doi.org/10.1016/j.jcis.2021.11.062
Autor:
Sarah L. Withey, Lei Cao, Fernando B. de Moura, Kenroy R. Cayetano, Michael L. Rohan, Jack Bergman, Stephen J. Kohut
Publikováno v:
Brain Imaging and Behavior. 16:1684-1694
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee00d6b7b9d192577ef44e3bbf57b846
https://doi.org/10.1007/s11682-022-00639-4
https://doi.org/10.1007/s11682-022-00639-4
Autor:
Meining Wang, Thomas C. Irvin, Christine A. Herdman, Ramsey D. Hanna, Sergio A. Hassan, Yong-Sok Lee, Sophia Kaska, Rachel Saylor Crowley, Thomas E. Prisinzano, Sarah L. Withey, Carol A. Paronis, Jack Bergman, Saadet Inan, Ellen B. Geller, Martin W. Adler, Theresa A. Kopajtic, Jonathan L. Katz, Aaron M. Chadderdon, John R. Traynor, Arthur E. Jacobson, Kenner C. Rice
Publikováno v:
Molecules, Vol 25, Iss 11, p 2640 (2020)
(−)-N-Phenethyl analogs of optically pure N-norhydromorphone were synthesized and pharmacologically evaluated in several in vitro assays (opioid receptor binding, stimulation of [35S]GTPγS binding, forskolin-induced cAMP accumulation assay, and MO
Externí odkaz:
https://doaj.org/article/413521e5240a47c49d66570b815acccf
Autor:
U Wang Lei, Abrey J. Yeo, Keerat Junday, Ashmitha Sundarrajan, Michelle Pewarchuk, Hannah C Leeson, Amanda W. Kijas, Ernst J. Wolvetang, Sarah L. Withey, Dmitry A. Ovchinnikov, Martin F. Lavin
Publikováno v:
Human Molecular Genetics. 29:990-1001
Patients with ataxia-telangiectasia (A-T) lack a functional ATM kinase protein and exhibit defective repair of DNA double-stranded breaks and response to oxidative stress. We show that CRISPR/Cas9-assisted gene correction combined with piggyBac (PB)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4be0a21c534d1c7e2c36bc1c00b09a
https://doi.org/10.1093/hmg/ddaa023
https://doi.org/10.1093/hmg/ddaa023
Publikováno v:
Perspect Behav Sci
The effective management of pain is a longstanding public health concern. Although opioids have been frontline analgesics for decades, they also have well-known undesirable effects that limit their clinical utility, such as abuse liability and respir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68bd784cba31a6367b0216a99b55f3c
https://doi.org/10.1007/s40614-019-00239-6
https://doi.org/10.1007/s40614-019-00239-6
Autor:
Connor Rogerson, Edward Britton, Andrew D. Sharrocks, Sarah L. Withey, Neil A. Hanley, Yeng Ang
Publikováno v:
Rogerson, C, Britton, E, Withey, S, Hanley, N, Ang, Y S & Sharrocks, A D 2019, ' Identification of a primitive intestinal transcription factor network shared between esophageal adenocarcinoma and its precancerous precursor state ', Genome research, vol. 29, no. 5, pp. 723-736 . https://doi.org/10.1101/gr.243345.118
Esophageal adenocarcinoma (EAC) is one of the most frequent causes of cancer death, and yet compared to other common cancers, we know relatively little about the molecular composition of this tumor type. To further our understanding of this cancer, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe5f1c81ae6826180733364986d93d5c
https://doi.org/10.1101/gr.243345.118
https://doi.org/10.1101/gr.243345.118
Autor:
Gareth R. Willis, Sarah L. Withey
Publikováno v:
EBioMedicine
EBioMedicine, Vol 64, Iss, Pp 103210-(2021)
EBioMedicine, Vol 64, Iss, Pp 103210-(2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7a1f5e48ebd2089308eddefcb73c46
https://pubmed.ncbi.nlm.nih.gov/33530001
https://pubmed.ncbi.nlm.nih.gov/33530001