The promise, perceptions, and pitfalls of immunoassays for autoantibody testing in myositis

Autor: Sarah L. Tansley, Julia Snowball, John D. Pauling, Anya Lissina, Masataka Kuwana, Lisa G. Rider, Johan Rönnelid, Neil J. McHugh, on behalf of the International Myositis Assessment and Clinical Studies (IMACS) Group Myositis Autoantibody Scientific Interest Group

Publikováno v: Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-4 (2020)

Abstract Background A myositis-specific autoantibody can now be identified in the majority of patients with myositis. They identify homogeneous patient subgroups and are key tools in developing a personalized approach to disease management. There is

Externí odkaz: https://doaj.org/article/699e2b3a54944ccd86f92a2048285637

OA29 Blotting-based assays under-detected TIF1-gamma and NXP2 autoantibodies compared to immunoprecipitation in Juvenile Dermatomyositis cohorts

Autor: Huong D Nguyen, Charalampia Papadopoulou, Dario Cancemi, Lucy R Wedderburn, Sarah L Tansley

Publikováno v: Rheumatology Advances in Practice. 6

Introduction/Background The rare heterogenous autoimmune disease Juvenile Dermatomyositis (JDM) relies on prognostic tools including myositis specific antibodies (MSA) and myositis associated antibodies (MAA) to guide early treatment and reduce the r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::091f2a8fc5350289679c6908d6548717
https://doi.org/10.1093/rap/rkac066.029

Identification and prediction of novel classes of long-term disease trajectories for patients with juvenile dermatomyositis using growth mixture models

Autor: Charalampia Papadopoulou, Muthana Al-Obaidi, Lucy R. Wedderburn, Bianca De Stavola, Liza J McCann, Sarah L Tansley, Neil Martin, Neil McHugh, Sandrine Compeyrot-Lacassagne, Claire T Deakin, Clarissa Pilkington

Publikováno v: Rheumatology (Oxford, England)
2021, ' Identification and prediction of novel classes of long-term disease trajectories for patients with juvenile dermatomyositis using growth mixture models ', Rheumatology (Oxford, England), vol. 60, no. 4, pp. 1891–1901 . https://doi.org/10.1093/rheumatology/keaa497

Objectives Uncertainty around clinical heterogeneity and outcomes for patients with JDM represents a major burden of disease and a challenge for clinical management. We sought to identify novel classes of patients having similar temporal patterns in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b932ab8aade8a5de2a239df5112c9b
http://europepmc.org/articles/PMC8023987

Bye-bye muscle biopsy, we have autoantibodies with us now

Autor: Victoria Riddell, Sarah L Tansley

Publikováno v: Indian Journal of Rheumatology, Vol 15, Iss 6, Pp 74-80 (2020)

Muscle biopsy is generally considered the gold standard diagnostic tool for patients with presenting with features suggestive of idiopathic inflammatory myopathy. Muscle biopsy is however an invasive test, the histopathological findings can be influe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202fcc6379d7bfbd5564ab5b8b82ed98
http://www.indianjrheumatol.com/article.asp?issn=0973-3698

British Society for Rheumatology guideline on management of paediatric, adolescent and adult patients with idiopathic inflammatory myopathy

Autor: Alexander G S, Oldroyd, James B, Lilleker, Tania, Amin, Octavio, Aragon, Katie, Bechman, Verna, Cuthbert, James, Galloway, Patrick, Gordon, William J, Gregory, Harsha, Gunawardena, Michael G, Hanna, David, Isenberg, John, Jackman, Patrick D W, Kiely, Polly, Livermore, Pedro M, Machado, Sue, Maillard, Neil, McHugh, Ruth, Murphy, Clarissa, Pilkington, Athiveeraramapandian, Prabu, Phoebe, Rushe, Stefan, Spinty, Joanne, Swan, Hasan, Tahir, Sarah L, Tansley, Paul, Truepenny, Yvonne, Truepenny, Kishore, Warrier, Mark, Yates, Charalampia, Papadopoulou, Neil, Martin, Liza, McCann, Hector, Chinoy

Publikováno v: Oldroyd, A, Lilleker, J, Amin, T, Aragon, O, Bechman, K, Cuthbert, V, Galloway, J, Gordon, P, Gregory, W, Gunawardena, H, Hanna, M G, Isenberg, D, Jackman, J, Kiely, P D W, Livermore, P, Machado, P M, Maillard, S, McHugh, N, Murphy, R, Pilkington, C, Prabu, A, Rushe, P, Spinty, S, Swan, J, Tahir, H, Tansley, S L, Truepenny, P, Truepenny, Y, Warrier, K, Yates, M, Papadopoulou, C, Martin, N, McCann, L & Chinoy, H 2022, ' British Society for Rheumatology guideline on management of paediatric, adolescent, and adult patients with idiopathic inflammatory myopathy ', Rheumatology . https://doi.org/10.1093/rheumatology/keac115

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435ec4492f1f8702e91f8ee44568cd80
https://pubmed.ncbi.nlm.nih.gov/35355064