Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Sarah L. Rouse"'
Autor:
Punam Rattu, Flo Glencross, Sophie L. Mader, Chris-Kriton Skylaris, Stephen J. Matthews, Sarah L. Rouse, Syma Khalid
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 6417-6430 (2021)
Two proteins of the Escherichia coli membrane protein complex, CsgG and CsgF, are studied as proteinaceous nanopores for DNA sequencing. It is highly desirable to control the DNA as it moves through the pores, this requires characterisation of DNA tr
Externí odkaz:
https://doaj.org/article/fd4ef18f4e964d0f82717acf95699cd1
Autor:
Paul Murphy, Yingqi Xu, Sarah L. Rouse, Ellis G. Jaffray, Anna Plechanovová, Steve J. Matthews, J. Carlos Penedo, Ronald T. Hay
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
RNF4 is a prototypical single-subunit E3 enzyme that can bind both substrate and ubiquitin-loaded E2. Here, the authors show that the RNF4 N-terminal region, although lacking a defined secondary structure, maintains a compact global conformation to f
Externí odkaz:
https://doaj.org/article/c9de74e062a44078a1b0ae8e8b67bf15
Autor:
Sophie McKenna, Enrico Malito, Sarah L. Rouse, Francesca Abate, Giuliano Bensi, Emiliano Chiarot, Francesca Micoli, Francesca Mancini, Danilo Gomes Moriel, Guido Grandi, Danuta Mossakowska, Max Pearson, Yingqi Xu, James Pease, Shiranee Sriskandan, Immaculada Margarit, Matthew J. Bottomley, Stephen Matthews
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 650-660 (2020)
Over 18 million disease cases and half a million deaths worldwide are estimated to be caused annually by Group A Streptococcus. A vaccine to prevent GAS disease is urgently needed. SpyCEP (Streptococcus pyogenes Cell-Envelope Proteinase) is a surface
Externí odkaz:
https://doaj.org/article/b595bca1fd7a42ec867d442b4d2f3cb2
Autor:
Punam Rattu, Flo Glencross, Sophie L. Mader, Chris-Kriton Skylaris, Stephen J. Matthews, Sarah L. Rouse, Syma Khalid
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 1027- (2022)
Externí odkaz:
https://doaj.org/article/237975da14904d9a883d4d7d50bfed58
Autor:
Xeni Miliara, Takashi Tatsuta, Jamie-Lee Berry, Sarah L. Rouse, Kübra Solak, Dror S. Chorev, Di Wu, Carol V. Robinson, Stephen Matthews, Thomas Langer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The Ups/PRELI family mediates intramitochondrial lipid distribution and synthesis by shuttling phospholipids between both mitochondrial membranes. Here the authors combine X-ray crystallography, MD simulations and yeast genetic screens and identify r
Externí odkaz:
https://doaj.org/article/51be78de046c436f8df261a65888f530
Autor:
Amit Kumar, Xu Zhang, Oscar Vadas, Fisentzos A. Stylianou, Nicolas Dos Santos Pacheco, Sarah L. Rouse, Marc L. Morgan, Dominique Soldati-Favre, Steve Matthews
Publikováno v:
Crystals, Vol 12, Iss 1, p 110 (2022)
A model for parasitic motility has been proposed in which parasite filamentous actin (F-actin) is attached to surface adhesins by a large component of the glideosome, known as the glideosome-associated connector protein (GAC). This large 286 kDa prot
Externí odkaz:
https://doaj.org/article/07888b24129a409faa8df7d6ea879631
Autor:
Sarah L. Rouse, William J. Hawthorne, Jamie-Lee Berry, Dror S. Chorev, Sandra A. Ionescu, Sebastian Lambert, Fisentzos Stylianou, Wiebke Ewert, Uma Mackie, R. Marc L. Morgan, Daniel Otzen, Florian-Alexander Herbst, Per H. Nielsen, Morten Dueholm, Hagan Bayley, Carol V. Robinson, Stephen Hare, Stephen Matthews
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Gram-negative bacteria assemble biofilms from amyloid fibres, which translocate across the outer membrane as unfolded amyloid precursors through a secretion system. Here, the authors characterise the structural details of the amyloid transporter FapF
Externí odkaz:
https://doaj.org/article/afb451a29eaf4948a6eaf6a24df04339
Autor:
Amit Kumar, Oscar Vadas, Nicolas Dos Santos Pacheco, Xu Zhang, Kin Chao, Nicolas Darvill, Helena Ø Rasmussen, Yingqi Xu, Gloria Meng-Hsuan Lin, Fisentzos A Stylianou, Jan Skov Pedersen, Sarah L Rouse, Marc L Morgan, Dominique Soldati-Favre, Stephen Matthews
Publikováno v:
Kumar, A, Vadas, O, Dos Santos Pacheco, N, Zhang, X, Chao, K, Darvill, N, Rasmussen, H Ø, Xu, Y, Lin, G M-H, Stylianou, F A, Pedersen, J S, Rouse, S L, Morgan, M L, Soldati-Favre, D & Matthews, S 2023, ' Structural and regulatory insights into the glideosome-associated connector from Toxoplasma gondii ', eLife, vol. 12 . https://doi.org/10.7554/eLife.86049
The phylum of Apicomplexa groups intracellular parasites that employ substrate-dependent gliding motility to invade host cells, egress from the infected cells, and cross biological barriers. The glideosome-associated connector (GAC) is a conserved pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bcdeb04e5a4e623d5f3af8c20553026
https://pure.au.dk/portal/da/publications/structural-and-regulatory-insights-into-the-glideosomeassociated-connector-from-toxoplasma-gondii(882484a3-51a4-4027-b7cc-e5abd3338998).html
https://pure.au.dk/portal/da/publications/structural-and-regulatory-insights-into-the-glideosomeassociated-connector-from-toxoplasma-gondii(882484a3-51a4-4027-b7cc-e5abd3338998).html
Autor:
Amit Kumar, Oscar Vadas, Nicolas Dos Santos Pacheco, Xu Zhang, Kin Chao, Nicolas Darvill, Helena Ø Rasmussen, Yingqi Xu, Gloria Meng-Hsuan Lin, Fisentzos A Stylianou, Jan Skov Pedersen, Sarah L Rouse, Marc L Morgan, Dominique Soldati-Favre, Stephen Matthews
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aad9ed1eb2a1c5ad210f3f4ac800e1a
https://doi.org/10.7554/elife.86049.sa2
https://doi.org/10.7554/elife.86049.sa2
Autor:
Amit Kumar, Oscar Vadas, Nicolas Dos Santos Pacheco, Xu Zhang, Kin Chao, Nicolas Darvill, Helena Ø. Rasmussen, Yingqi Xu, Gloria Lin, Fisentzos A Stylianou, Jan Skov Pedersen, Sarah L. Rouse, Marc L. Morgan, Dominique Soldati-Favre, Steve Matthews
The phylum of Apicomplexa groups intracellular parasites that employ substratedependent gliding motility to invade host cells, egress from the infected cells and cross biological barriers. The glideosome associated connector (GAC) is a conserved prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6392bc8ff6b98f1054bed4c4d50dba8
https://doi.org/10.1101/2023.01.23.525158
https://doi.org/10.1101/2023.01.23.525158