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pro vyhledávání: '"Sarah L. Pallas"'
Refinement of developing visual projections is reported to depend on visual experience in rats, cats, ferrets, and monkeys. Visual deprivation in these species delays visual pathway development, reportedly maintaining a juvenile condition and prolong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9f341d4c8d86e5d11e8ea783f502353
https://doi.org/10.1101/2022.10.06.511220
https://doi.org/10.1101/2022.10.06.511220
Autor:
Sarah L. Pallas
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
Evolution and development are interdependent, particularly with regard to the construction of the nervous system and its position as the machine that produces behavior. On the one hand, the processes directing development and plasticity of the brain
Externí odkaz:
https://doaj.org/article/df372342309e42d38bd2d29430cace0d
Autor:
Yu-Ting Mao, Sarah L. Pallas
Publikováno v:
Neural Plasticity, Vol 2013 (2013)
Loss of sensory input from peripheral organ damage, sensory deprivation, or brain damage can result in adaptive or maladaptive changes in sensory cortex. In previous research, we found that auditory cortical tuning and tonotopy were impaired by cross
Externí odkaz:
https://doaj.org/article/908251e4377e4c73ac639df4152bab18
Autor:
James P Carson, Tao Ju, Hui-Chen Lu, Christina Thaller, Mei Xu, Sarah L Pallas, Michael C Crair, Joe Warren, Wah Chiu, Gregor Eichele
Publikováno v:
PLoS Computational Biology, Vol 1, Iss 4, p e41 (2005)
Massive amounts of data are being generated in an effort to represent for the brain the expression of all genes at cellular resolution. Critical to exploiting this effort is the ability to place these data into a common frame of reference. Here we ha
Externí odkaz:
https://doaj.org/article/114c931ac2d846c988f5ee8e4d7a0250
The topographically ordered retinocollicular projection is an excellent system for studying the mechanism of axon guidance. Gradients of EphA receptors in the retina and ephrin-As in the superior colliculus (SC) pattern the anteroposterior axis of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c1436a5726957e40d3933242a389b7e
https://europepmc.org/articles/PMC6506164/
https://europepmc.org/articles/PMC6506164/
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 39(23)
During a critical period in postnatal development, spontaneous and evoked retinal activity shape nascent visual pathways in an adaptive fashion. Visual experience increases transcription of the neurotrophin BDNF, activating the BDNF receptor TrkB, wh
Autor:
Timothy S. Balmer, Sarah L. Pallas
Publikováno v:
Journal of Neurophysiology. 113:2049-2061
Progressive loss of plasticity during development prevents refined circuits from regressing to an immature state and is thought to depend on maturation of GABAergic inhibition. For example, a gradual reduction in size of visual receptive fields (RFs)
Publikováno v:
Developmental Neurobiology. 79:i-i
Autor:
Timothy S. Balmer, Sarah L. Pallas
Publikováno v:
Cerebral Cortex. 25:904-917
Visual deprivation is reported to prevent or delay the development of mature receptive field (RF) properties in primary visual cortex (V1) in several species. In contrast, visual deprivation neither prevents nor delays refinement of RF size in the su
Publikováno v:
Journal of Neurophysiology. 105:1558-1573
Sensory neocortex is capable of considerable plasticity after sensory deprivation or damage to input pathways, especially early in development. Although plasticity can often be restorative, sometimes novel, ectopic inputs invade the affected cortical