Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Sarah L. Long"'
Autor:
Paul M. Ryan, Ellen H. Stolte, Lis E. E. London, Jerry M. Wells, Sarah L. Long, Susan A. Joyce, Cormac G. M. Gahan, Gerald F. Fitzgerald, R. Paul Ross, Noel M. Caplice, Catherine Stanton
Publikováno v:
BMC Microbiology, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background Lactobacillus mucosae DPC 6426 has previously demonstrated potentially cardio-protective properties, in the form of dyslipidaemia and hypercholesterolemia correction in an apolipoprotein-E deficient mouse model. This study aims to
Externí odkaz:
https://doaj.org/article/2d5e7ab98b354c8aa6f02f793862ed01
Autor:
Dmitry S. Karlov, Sarah L. Long, Ximin Zeng, Fuzhou Xu4, Kanhaya Lal, Liu Cao, Karim Hayoun, Jun Lin, Susan A. Joyce, Irina G. Tikhonova
The input files of BSH molecular dynamics simulations, and simulation trajectories analysis are provided.
Bile Salt Hydrolases (BSHs) are currently investigated as target enzymes for metabolic regulators in humans and growth promoters in farm an
Bile Salt Hydrolases (BSHs) are currently investigated as target enzymes for metabolic regulators in humans and growth promoters in farm an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089cd13d25b85e6c96b9e7cc62f4389b
Autor:
Sarah L. Long, Susan A. Joyce
Bile acids (BAs), biological detergents for nutrient digestion, are important local and systemic signalling molecules to interact with a variety of cell receptors central to influence host responses. While BAs are synthesized in the liver, the range
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e96c3b777a9c3f78b073c6063ab577f
https://doi.org/10.1101/2022.06.24.497474
https://doi.org/10.1101/2022.06.24.497474
Autor:
Dmitry S. Karlov, Sarah L. Long, Ximin Zeng, Fuzhou Xu, Kanhaya Lal, Liu Cao, Karim Hayoun, Jun Lin, Susan A. Joyce, Irina G. Tikhonova
Publikováno v:
Karlov, D S, Long, S L, Zeng, X, Xu, F, Lal, K, Cao, L, Hayoun, K, Lin, J, Joyce, S A & Tikhonova, I G 2023, ' Characterization of the mechanism of bile salt hydrolase substrate specificity by experimental and computational analyses ', Structure, vol. 31, no. 5, pp. 629-638.e5 . https://doi.org/10.1016/j.str.2023.02.014
Bile Salt Hydrolases (BSHs) are currently investigated as target enzymes for metabolic regulators in humans and growth promoters in farm animals. Understanding structural features underlying substrate specificity is necessary for inhibitor design. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a0e1beb86af2a45450d162db3c0903
https://doi.org/10.1016/j.str.2023.02.014
https://doi.org/10.1016/j.str.2023.02.014
Publikováno v:
Nature ecologyevolution. 5(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c7227c9acfbcc030e62224809904b06
https://pubmed.ncbi.nlm.nih.gov/34089027
https://pubmed.ncbi.nlm.nih.gov/34089027
Publikováno v:
FEMS microbiology letters. 367(10)
Lactic acid bacterium, Lactobacillus plantarum, has been applied, for centuries, for food and drink fermentations. Given the benefits associated with fermented products, Lb. plantarum strains have captured considerable industrial and scientific inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0aba000ede1ddf5990d84d4c202f88
https://pubmed.ncbi.nlm.nih.gov/32386211
https://pubmed.ncbi.nlm.nih.gov/32386211
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-20 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-20 (2020)
Gut microbial enzymes, bile salt hydrolases (BSHs) are the gateway enzymes for bile acid (BA) modification in the gut. This activity is a promising target for developing innovative non-antibiotic growth promoters to enhance animal production and heal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3c0ecb0c4830bc80c24092c416a029
http://europepmc.org/articles/PMC7080769
http://europepmc.org/articles/PMC7080769
Publikováno v:
Molecular Aspects of Medicine. 56:54-65
Bile acids are synthesized from cholesterol in the liver and released into the intestine to aid the digestion of dietary lipids. The host enzymes that contribute to bile acid synthesis in the liver and the regulatory pathways that influence the compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33055c63b18ead2a8594969bfcc5505
https://doi.org/10.1016/j.mam.2017.06.002
https://doi.org/10.1016/j.mam.2017.06.002
Autor:
Sarah L. Long, Gerald F. Fitzgerald, Catherine Stanton, R. Paul Ross, Jerry M. Wells, Ellen H. Stolte, Cormac G. M. Gahan, Lis E. E. London, Susan A. Joyce, Paul M. Ryan, Noel M. Caplice
Publikováno v:
BMC Microbiology
BMC Microbiology, Vol 19, Iss 1, Pp 1-13 (2019)
BMC Microbiology 19 (2019) 1
BMC Microbiology, 19(1)
BMC Microbiology, Vol 19, Iss 1, Pp 1-13 (2019)
BMC Microbiology 19 (2019) 1
BMC Microbiology, 19(1)
Background Lactobacillus mucosae DPC 6426 has previously demonstrated potentially cardio-protective properties, in the form of dyslipidaemia and hypercholesterolemia correction in an apolipoprotein-E deficient mouse model. This study aims to characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ffe34875d75087ea6a1168374bb246
https://zenodo.org/record/2561530
https://zenodo.org/record/2561530
Autor:
Sarah L. Long, David I. Mackinnon
Publikováno v:
Paleontological Research. 13:309-317
A new species of laqueoid brachiopod from Macclesfield Bank, South China Sea, Shimodaia macclesfieldensis sp. nov., is described and compared with the Japanese type species of the genus Shimodaia, S. pterygiota MacKinnon, Saito, and Endo, 1997. S. ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c911c52568f7c8ba816ef31a30ce8fed
https://doi.org/10.2517/1342-8144-13.4.309
https://doi.org/10.2517/1342-8144-13.4.309