Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sarah L. Hayward"'
Publikováno v:
mBio, Vol 3, Iss 6 (2012)
ABSTRACT Respiratory syncytial virus (RSV) is the most common viral cause of severe lower respiratory tract illness in infants and children. The virus replicates in polarized epithelial cells in the airway and, to a lesser extent, infects airway anti
Externí odkaz:
https://doaj.org/article/81d852e0441447de97bf1bb118ca5bfc
Autor:
Alison Swaims-Kohlmeier, Alexander N. Wein, Felica P. Hardnett, Anandi N. Sheth, Zheng-Rong Tiger Li, M. Elliot Williams, Jessica Radzio-Basu, HaoQiang Zheng, Chuong Dinh, Lisa B. Haddad, Elizabeth M.B. Collins, Jenna L. Lobby, Kirsten Kost, Sarah L. Hayward, Igho Ofotokun, Rustom Antia, Christopher D. Scharer, Anice C. Lowen, J. Gerardo Garcia-Lerma, Jacob E. Kohlmeier
Despite their importance for immunity against sexually transmitted infections (STIs), the composition of the female reproductive tract (FRT) memory CD4 T cell population in response to changes in the local tissue environment during the menstrual cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e86e42516ff915ae2e2ddcbe8251df1c
https://doi.org/10.1101/2022.10.01.510445
https://doi.org/10.1101/2022.10.01.510445
Autor:
Ida E M Uddbäck, Sarah L. Hayward, Alexander N. Wein, Jenna L. Lobby, Allan Randrup Thomsen, Emily K. Cartwright, Jacob E. Kohlmeier, Shiki Takamura, Jan Pravsgaard Christensen, Amalie Skak Schøller
Publikováno v:
Mucosal immunology
Tissue resident memory T cells (TRM) in the lungs are pivotal for protection against repeated infection with respiratory viruses. However, the gradual loss of these cells over time and the associated decline in clinical protection represent a serious
Autor:
Christopher D. Scharer, Sarah L. Hayward, Jeremy M. Boss, Jacob E. Kohlmeier, Emily K. Cartwright, Shiki Takamura, Zheng-Rong Tiger Li
Publikováno v:
Nature Immunology
Tissue-resident memory T cells (TRM cells) are critical for cellular immunity to respiratory pathogens and reside in both the airways and the interstitium. In the present study, we found that the airway environment drove transcriptional and epigeneti
Autor:
Shiki Takamura, Nivedha Kumar, Alexander N. Wein, Sarah L. Hayward, Jacob E. Kohlmeier, Tetsuo Tsukamoto, Zheng-Rong Tiger Li, Paul Dunbar, Satoshi Ueha, Emily K. Cartwright, Ida E M Uddbäck
Publikováno v:
Mucosal Immunology. 13:161-171
Lung resident memory CD8 T cells (TRM) are critical for protection against respiratory viruses, but the cellular interactions required for their development are poorly understood. Herein we describe the necessity of classical monocytes for the establ
Autor:
Sean R. McMaster, Timothy L. Denning, Alexander N. Wein, Jacob E. Kohlmeier, Sarah L. Hayward, Emily K. Cartwright, Paul Dunbar
Publikováno v:
Mucosal immunology
Resident memory CD8 T (TRM) cells in the lung parenchyma (LP) and airways provide heterologous protection against influenza virus challenge. However, scant knowledge exists regarding factors necessary to establish and maintain lung CD8 TRM. Here we d
Autor:
Jenna L Lobby, Ida Uddback, Emily Cartwright, Sarah L Hayward, Shiki Takamura, Allan R Thomsen, Jan Christensen, Jacob E Kohlmeier
Publikováno v:
The Journal of Immunology. 204:85.5-85.5
Lung tissue-resident memory T cells (TRM) are crucial mediators of cellular immunity against influenza viruses, but the number of these cells in the lung tissue gradually declines in the months following influenza infection. Recently, we showed that
Autor:
Emily K. Cartwright, Shiki Takamura, Daniel T. McManus, Makoto Kurachi, Kouji Matsushima, Takeshi Shimaoka, Paul Dunbar, Sean R. McMaster, Alexander N. Wein, Sarah L. Hayward, Tomoko Masumoto, Tatsuya Tsukui, Satoshi Ueha, Jacob E. Kohlmeier
Publikováno v:
The Journal of Experimental Medicine
Lung TRM cells are present in both the interstitium and airways, but factors regulating their localization to these distinct sites are unknown. This work shows that the CXCR6/CXCL16 axis governs the partitioning of TRM cells to different compartments
Autor:
Paul R, Dunbar, Emily K, Cartwright, Alexander N, Wein, Tetsuo, Tsukamoto, Zheng-Rong, Tiger Li, Nivedha, Kumar, Ida E, Uddbäck, Sarah L, Hayward, Satoshi, Ueha, Shiki, Takamura, Jacob E, Kohlmeier
Publikováno v:
Mucosal immunology
Lung resident memory CD8 T cells (TRM) are critical for protection against respiratory viruses, but the cellular interactions required for their development are poorly understood. Herein we describe the necessity of classical monocytes for the establ
Autor:
Griffith D. Parks, Beth C. Holbrook, Sarah L. Hayward, Martha A. Alexander-Miller, Tyler Aycock, Nancy D. Kock, Lance K. Blevins
Publikováno v:
Virology. 476:124-133
Respiratory infection of young infants results in increased morbidity and mortality compared to infection of adults. In spite of the significance of this health issue, our understanding of the immune response elicited in infants, especially in the re