Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Sarah L Waters"'
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 8, p e1007961 (2020)
Tumour spheroids are widely used as an in vitro assay for characterising the dynamics and response to treatment of different cancer cell lines. Their popularity is largely due to the reproducible manner in which spheroids grow: the diffusion of nutri
Externí odkaz:
https://doaj.org/article/99d7b95699f64d4489e431f58cdd5e9a
Autor:
Michael J Chen, Jonathan P Whiteley, Colin P Please, Franziska Ehlicke, Sarah L Waters, Helen M Byrne
Publikováno v:
Journal of Tissue Engineering, Vol 10 (2019)
A key step in the tissue engineering of articular cartilage is the chondrogenic differentiation of mesenchymal stem cells (MSCs) into chondrocytes (native cartilage cells). Chondrogenesis is regulated by transforming growth factor- β (TGF- β ), a s
Externí odkaz:
https://doaj.org/article/6c223b1bbe114660b51045dad77469b1
Autor:
Candice Ashmore-Harris, Evangelia Antonopoulou, Rhona E. Aird, Tak Yung Man, Simon M. Finney, Annelijn M. Speel, Wei-Yu Lu, Stuart J. Forbes, Victoria L. Gadd, Sarah L. Waters
Publikováno v:
npj Regenerative Medicine, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Currently liver transplantation is the only treatment option for liver disease, but organ availability cannot meet patient demand. Alternative regenerative therapies, including cell transplantation, aim to modulate the injured microenvironme
Externí odkaz:
https://doaj.org/article/ae12cbb445934c8a8595557d05d68977
Autor:
Candice Ashmore-Harris, Evangelia Antonopoulou, Simon M. Finney, Melissa R. Vieira, Matthew G. Hennessy, Andreas Muench, Wei-Yu Lu, Victoria L. Gadd, Alicia J. El Haj, Stuart J. Forbes, Sarah L. Waters
Publikováno v:
npj Regenerative Medicine, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract Cell therapies are emerging as promising treatments for a range of liver diseases but translational bottlenecks still remain including: securing and assessing the safe and effective delivery of cells to the disease site; ensuring successful
Externí odkaz:
https://doaj.org/article/ae003db3cf7c435db3b3e580984070d7
Autor:
Lloyd A C Chapman, Rebecca J Shipley, Jonathan P Whiteley, Marianne J Ellis, Helen M Byrne, Sarah L Waters
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105813 (2014)
The need for efficient and controlled expansion of cell populations is paramount in tissue engineering. Hollow fibre bioreactors (HFBs) have the potential to meet this need, but only with improved understanding of how operating conditions and cell se
Externí odkaz:
https://doaj.org/article/e8d7f704587d42848b1366cb2516c3ab
Autor:
Pedro Amado, Shaokai Zheng, Dirk Lange, Dario Carugo, Sarah L. Waters, Dominik Obrist, Fiona Burkhard, Francesco Clavica
Publikováno v:
Frontiers in Urology, Vol 3 (2024)
Ureteral stents are hollow tubes that are inserted into the ureter to maintain the flow of urine from the kidney to the bladder. However, the use of these indwelling stents is associated with potential complications. Biofilm, an organized consortium
Externí odkaz:
https://doaj.org/article/3009d12153e8459a9289644f98f77bbf
Publikováno v:
Frontiers in Urology, Vol 3 (2023)
In ureteroscopy, a common method for kidney stone removal, a ureteroscope is inserted into the patient’s kidney, through which working tools such as a laser are inserted. During the procedure, the renal space proximal to the scope tip is irrigated
Externí odkaz:
https://doaj.org/article/6eb3e4129c324800973fbbe439ea96a3
Autor:
Barbara Schamberger, Ricardo Ziege, Karine Anselme, Martine Ben Amar, Michał Bykowski, André P. G. Castro, Amaia Cipitria, Rhoslyn A. Coles, Rumiana Dimova, Michaela Eder, Sebastian Ehrig, Luis M. Escudero, Myfanwy E. Evans, Paulo R. Fernandes, Peter Fratzl, Liesbet Geris, Notburga Gierlinger, Edouard Hannezo, Aleš Iglič, Jacob J. K. Kirkensgaard, Philip Kollmannsberger, Łucja Kowalewska, Nicholas A. Kurniawan, Ioannis Papantoniou, Laurent Pieuchot, Tiago H. V. Pires, Lars D. Renner, Andrew O. Sageman‐Furnas, Gerd E. Schröder‐Turk, Anupam Sengupta, Vikas R. Sharma, Antonio Tagua, Caterina Tomba, Xavier Trepat, Sarah L. Waters, Edwina F. Yeo, Andreas Roschger, Cécile M. Bidan, John W. C. Dunlop
Publikováno v:
Advanced Materials
Schamberger, B, Ziege, R, Anselme, K, Ben Amar, M, Bykowski, M, Castro, A P G, Cipitria, A, Coles, R A, Dimova, R, Eder, M, Ehrig, S, Escudero, L M, Evans, M E, Fernandes, P R, Fratzl, P, Geris, L, Gierlinger, N, Hannezo, E, Iglič, A, Kirkensgaard, J J K, Kollmannsberger, P, Kowalewska, Ł, Kurniawan, N A, Papantoniou, I, Pieuchot, L, Pires, T H V, Renner, L D, Sageman-Furnas, A O, Schröder-Turk, G E, Sengupta, A, Sharma, V R, Tagua, A, Tomba, C, Trepat, X, Waters, S L, Yeo, E F, Roschger, A, Bidan, C M & Dunlop, J W C 2023, ' Curvature in Biological Systems : Its Quantification, Emergence, and Implications across the Scales ', Advanced Materials, vol. 35, no. 13, 2206110 . https://doi.org/10.1002/adma.202206110
Schamberger, B, Ziege, R, Anselme, K, Ben Amar, M, Bykowski, M, Castro, A P G, Cipitria, A, Coles, R A, Dimova, R, Eder, M, Ehrig, S, Escudero, L M, Evans, M E, Fernandes, P R, Fratzl, P, Geris, L, Gierlinger, N, Hannezo, E, Iglič, A, Kirkensgaard, J J K, Kollmannsberger, P, Kowalewska, Ł, Kurniawan, N A, Papantoniou, I, Pieuchot, L, Pires, T H V, Renner, L D, Sageman-Furnas, A O, Schröder-Turk, G E, Sengupta, A, Sharma, V R, Tagua, A, Tomba, C, Trepat, X, Waters, S L, Yeo, E F, Roschger, A, Bidan, C M & Dunlop, J W C 2023, ' Curvature in Biological Systems : Its Quantification, Emergence, and Implications across the Scales ', Advanced Materials, vol. 35, no. 13, 2206110 . https://doi.org/10.1002/adma.202206110
Surface curvature both emerges from, and influences the behavior of, living objects at length scales ranging from cell membranes to single cells to tissues and organs. The relevance of surface curvature in biology is supported by numerous experimenta
Autor:
Solveig A. van der Vegt, Ying-Jie Wang, Liudmila Polonchuk, Ken Wang, Sarah L. Waters, Ruth E. Baker
Publikováno v:
Frontiers in pharmacology. 13
Immune checkpoint inhibitors (ICIs), as a novel immunotherapy, are designed to modulate the immune system to attack malignancies. Despite their promising benefits, immune-related adverse events (IRAEs) may occur, and incidences are bound to increase
Autor:
Tom Quaiser, Sarah L. Waters, Philip S. Macklin, Christopher W. Pugh, Helen M. Byrne, Franziska Braun, Joshua A. Bull
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Digital pathology enables computational analysis algorithms to be applied at scale to histological images. An example is the identification of immune cells within solid tumours. Image analysis algorithms can extract precise cell locations from immuno