Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Sarah L O'Beirne"'
Autor:
Wu-Lin Zuo, Mahboubeh R Rostami, Michelle LeBlanc, Robert J Kaner, Sarah L O'Beirne, Jason G Mezey, Philip L Leopold, Karsten Quast, Sudha Visvanathan, Jay S Fine, Matthew J Thomas, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0237529 (2020)
Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic fibrotic lung disease with an irreversible decline of lung function. "Bronchiolization", characterized by ectopic appearance of airway epithelial cells in the alveolar regions, is one of t
Externí odkaz:
https://doaj.org/article/0145c5d89b5d45929b0413cd0eb395e9
Autor:
Sarah L O'Beirne, Jacqueline Salit, Juan L Rodriguez-Flores, Michelle R Staudt, Charbel Abi Khalil, Khalid A Fakhro, Amal Robay, Monica D Ramstetter, Joel A Malek, Mahmoud Zirie, Amin Jayyousi, Ramin Badii, Ajayeb Al-Nabet Al-Marri, Abdulbari Bener, Mai Mahmoud, Maria J Chiuchiolo, Alya Al-Shakaki, Omar Chidiac, Dora Stadler, Jason G Mezey, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0199837 (2018)
BACKGROUND:Type 2 diabetes (T2D) susceptibility is influenced by genetic and lifestyle factors. To date, the majority of genetic studies of T2D have been in populations of European and Asian descent. The focus of this study is on genetic variations u
Externí odkaz:
https://doaj.org/article/3bc29196bf8746a88fb56c0bfb23126d
Autor:
Sarah L O'Beirne, Jacqueline Salit, Juan L Rodriguez-Flores, Michelle R Staudt, Charbel Abi Khalil, Khalid A Fakhro, Amal Robay, Monica D Ramstetter, Iman K Al-Azwani, Joel A Malek, Mahmoud Zirie, Amin Jayyousi, Ramin Badii, Ajayeb Al-Nabet Al-Marri, Maria J Chiuchiolo, Alya Al-Shakaki, Omar Chidiac, Maey Gharbiah, Abdulbari Bener, Dora Stadler, Neil R Hackett, Jason G Mezey, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0156834 (2016)
The prevalence of type 2 diabetes (T2D) is increasing in the Middle East. However, the genetic risk factors for T2D in the Middle Eastern populations are not known, as the majority of studies of genetic risk for T2D are in Europeans and Asians.All su
Externí odkaz:
https://doaj.org/article/23fe42e26a404d9889315c23e2c9f95d
Autor:
Sarah L O'Beirne, Jacqueline Salit, Juan L Rodriguez-Flores, Michelle R Staudt, Charbel Abi Khalil, Khalid A Fakhro, Amal Robay, Monica D Ramstetter, Iman K Al-Azwani, Joel A Malek, Mahmoud Zirie, Amin Jayyousi, Ramin Badii, Ajayeb Al-Nabet Al-Marri, Maria J Chiuchiolo, Alya Al-Shakaki, Omar Chidiac, Maey Gharbiah, Abdulbari Bener, Dora Stadler, Neil R Hackett, Jason G Mezey, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161910 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0156834.].
Externí odkaz:
https://doaj.org/article/83b5fcc2d5ee4b2380283a0d191ee0c8
Autor:
Kihwan Kim, William Z. Zhang, Sarah Ann Kikkers, Sarah L. O’Beirne, Yael Strulovici-Barel, Robert J. Kaner, Ronald G. Crystal, Suzanne M. Cloonan
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 68:458-462
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fd5d20d94c0aa3f256b8c4c1d920092
https://doi.org/10.1165/rcmb.2022-0372le
https://doi.org/10.1165/rcmb.2022-0372le
Autor:
Anita L. Oh, Richard A. Mularski, Igor Barjaktarevic, R. Graham Barr, Russell P. Bowler, Alejandro P. Comellas, Christopher B. Cooper, Gerard J. Criner, MeiLan K. Han, Nadia N. Hansel, Eric A. Hoffman, Richard E. Kanner, Jerry A. Krishnan, Robert Paine, Trisha M. Parekh, Stephen P. Peters, Stephanie A. Christenson, Prescott G. Woodruff, Wayne H. Anderson, Mehrdad Arjomandi, Nirav Bhakta, Surya P. Bhatt, Russell Buhr, Jeffrey L. Curtis, M. Bradley Drummond, Victor Kim, Wassim Labaki, Allison Lambert, Stephen C. Lazarus, Alex Mackay, Wendy Moore, Sarah L. O'Beirne, Laura Paulin, Benjamin M. Smith, Donald P. Tashkin, James Michael Wells
Publikováno v:
Annals of the American Thoracic Society
Rationale: Diagnosis of chronic obstructive pulmonary disease (COPD) relies on abnormal spirometry. However, spirometry may underestimate the effects of smoking, missing smokers with respiratory di...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6221bf9c64d7d4193adfd2a8793fd47
https://doi.org/10.1513/annalsats.202006-757oc
https://doi.org/10.1513/annalsats.202006-757oc
Up-regulation of ACE2, the SARS-CoV-2 receptor, in asthmatics on maintenance inhaled corticosteroids
Autor:
Sarah L. O’Beirne, Yael Strulovici-Barel, Robert J. Kaner, Ronald G. Crystal, Jacqueline Salit
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-8 (2021)
Respiratory Research
Respiratory Research
Background The first step in SARS-CoV-2 infection is binding of the virus to angiotensin converting enzyme 2 (ACE2) on the airway epithelium. Asthma affects over 300 million people world-wide, many of whom may encounter SARS-CoV-2. Epidemiologic data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1c93276f4f5eac90ca764969c8971e
https://doaj.org/article/cd423978c73e4b28b23aeac1a498ee54
https://doaj.org/article/cd423978c73e4b28b23aeac1a498ee54
Autor:
Russell P. Bowler, Stephanie Jeong, Victor Kim, Fernando J. Martinez, Richard C. Boucher, Robert Paine, Mark T. Dransfield, MeiLan K. Han, Igor Barjaktarevic, J. Michael Wells, Stephen I. Rennard, Mehmet Kesimer, Wanda K. O'Neal, Jeffrey L. Curtis, Huaqing Zhao, Robert J. Kaner, Sarah L. O’Beirne, Christopher B. Cooper, Stephanie A. Christenson, Prescott G. Woodruff
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
COPD, chronic bronchitis (CB) and active smoking have all been associated with goblet cell hyperplasia (GCH) in small studies. Active smoking is strongly associated with CB, but there is a disconnect between CB clinical symptoms and pathology. Chroni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7ce6644ce81017abd5aa8d45f98c8a
http://link.springer.com/article/10.1038/s41598-020-77229-1
http://link.springer.com/article/10.1038/s41598-020-77229-1
Autor:
Mahboubeh Rostami, Philip L. Leopold, Ronald G. Crystal, Yael Strulovici-Barel, Sarah L. O’Beirne, Jason G. Mezey, Haijun Zhang
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Rationale: Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease (COVID-19), a predominantly respiratory illness. The first step in SARS-CoV-2 infection is binding of the virus to ACE2 (angiotensin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811201b189ff5da8f87eeb012241f67f
http://europepmc.org/articles/PMC7365377
http://europepmc.org/articles/PMC7365377
Autor:
Nancy P. Y. Chung, K. M. Faisal Khan, Mirko Andreoli, Robert J. Kaner, Sarah L. O’Beirne, Ronald G. Crystal
Publikováno v:
Scientific Reports. 12
With highly active anti-retroviral therapy (HAART), higher incidence of airway abnormalities is common in the HIV population consistent with the concept of accelerated lung “aging”. Our previous findings demonstrated that HIV induces human airway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305759531553789df1416d625212e457
https://doi.org/10.1038/s41598-022-06373-7
https://doi.org/10.1038/s41598-022-06373-7