Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Sarah L Maslen"'
Autor:
Andreas H Ehrensberger, Don-Marc Franchini, Philip East, Roger George, Nik Matthews, Sarah L Maslen, Jesper Q Svejstrup
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141250 (2015)
Externí odkaz:
https://doaj.org/article/abd65f3239a34b7ba3d560b3dea9b521
Autor:
Andreas H Ehrensberger, Don-Marc Franchini, Philip East, Roger George, Nik Matthews, Sarah L Maslen, Jesper Q Svejstrup
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0133246 (2015)
A protocol is presented for the isolation of native mammalian chromatin as fibers of 25-250 nucleosomes under conditions that preserve the natural epigenetic signature. The material is composed almost exclusively of histones and DNA and conforms to t
Externí odkaz:
https://doaj.org/article/1fe78f08e85f4033a0d681f092a4dba2
Autor:
Yuteng Wu, M. Teresa Bertran, Dhira Joshi, Sarah L. Maslen, Catherine Hurd, Louise J. Walport
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-9 (2023)
Abstract Photoaffinity labelling is a promising method for studying protein-ligand interactions. However, obtaining a specific, efficient crosslinker can require significant optimisation. We report a modified mRNA display strategy, photocrosslinking-
Externí odkaz:
https://doaj.org/article/ac80405cd43a480cbf4202f8da9ed517
Autor:
Leo Kiss, Tyler Rhinesmith, Jakub Luptak, Claire F. Dickson, Jonas Weidenhausen, Shannon Smyly, Ji-Chun Yang, Sarah L. Maslen, Irmgard Sinning, David Neuhaus, Dean Clift, Leo C. James
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract TRIM proteins are the largest family of E3 ligases in mammals. They include the intracellular antibody receptor TRIM21, which is responsible for mediating targeted protein degradation during Trim-Away. Despite their importance, the ubiquitin
Externí odkaz:
https://doaj.org/article/9847497c03534f53b81f80ff92484d91
Autor:
Tim Nierhaus, Stephen H. McLaughlin, Frank Bürmann, Danguole Kureisaite-Ciziene, Sarah L. Maslen, J. Mark Skehel, Conny W. H. Yu, Stefan M. V. Freund, Louise F. H. Funke, Jason W. Chin, Jan Löwe
Publikováno v:
Nature Microbiology. 7:1686-1701
During bacterial cell division, filaments of tubulin-like FtsZ form the Z-ring, which is the cytoplasmic scaffold for divisome assembly. In Escherichia coli, the actin homologue FtsA anchors the Z-ring to the membrane and recruits divisome components
Autor:
Sarah L. Maslen, Salvador Buse, Martin Spinck, Louise F. H. Funke, Daniel de la Torre, George P. C. Salmond, Wesley E. Robertson, Thomas S. Elliott, Franz L. Böge, Daniele Cervettini, Julius Fredens, Jason W. Chin, Yonka Christova, Kim C. Liu
Publikováno v:
Science. 372:1057-1062
Designing bacterial superpowers Biological systems read all 64 triplet codons in DNA to encode the synthesis of proteins composed of 20 canonical amino acids. Robertson et al. created cells that do not read several codons and showed that this confers
Autor:
Leo Kiss, Tyler Rhinesmith, Claire F Dickson, Jonas Weidenhausen, Shannon Smyly, Jakub Luptak, Ji-Chun Yang, Sarah L Maslen, Irmgard Sinning, David Neuhaus, Dean Clift, Leo C James
TRIM proteins are the largest family of E3 ligases in mammals. They include the intracellular antibody receptor TRIM21, which is responsible for mediating targeted protein degradation during Trim-Away. Despite their importance, the ubiquitination mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ff087e88dc61ef593889cbe848b8038
https://doi.org/10.1101/2022.06.29.498105
https://doi.org/10.1101/2022.06.29.498105
Autor:
Elyse S, Fischer, Conny W H, Yu, Johannes F, Hevler, Stephen H, McLaughlin, Sarah L, Maslen, Albert J R, Heck, Stefan M V, Freund, David, Barford
Publikováno v:
Nature communications. 13(1)
In response to improper kinetochore-microtubule attachments in mitosis, the spindle assembly checkpoint (SAC) assembles the mitotic checkpoint complex (MCC) to inhibit the anaphase-promoting complex/cyclosome, thereby delaying entry into anaphase. Th
Autor:
Sarah L. Maslen, Shun-ichiro Oda, Frank Adolf, Yorgo Modis, Iva A. Tchasovnikarova, Christopher H. Douse, Paul J. Lehner, Daniil M. Prigozhin, Stefan M.V. Freund, Anna Albecka, Laura E. Farleigh, Richard T. Timms
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 48, iss 18
Nucleic acids research, vol 48, iss 18
Transcription of integrated DNA from viruses or transposable elements is tightly regulated to prevent pathogenesis. The Human Silencing Hub (HUSH), composed of Periphilin, TASOR and MPP8, silences transcriptionally active viral and endogenous transge
Autor:
Shabih Shakeel, Christopher J. Russo, Gianluca Degliesposti, Pablo Alcón, Eeson Rajendra, J.M. Skehel, Ketan J. Patel, Sarah L. Maslen, Carol V. Robinson, Chris H. Hill, Dror S. Chorev, Francis J. O’Reilly, Juri Rappsilber, Shaoda He, Sjors H.W. Scheres, Lori A. Passmore
Publikováno v:
Shakeel, S, Rajendral, E, Alcón, P, O’Reilly, F J, Chorev, D S, Maslen, S, Degliesposti, G, Russo, C J, He, S, Hill, C H, Skehel, J M, Scheres, S H W, Patel, K J, Rappsilber, J, Robinson, C V & Passmore, L A 2019, ' Structure of the fanconi anaemia monoubiquitin ligase complex ', Nature, vol. 575, pp. 234-237 . https://doi.org/10.1038/s41586-019-1703-4
Nature
Nature
The Fanconi anaemia (FA) pathway repairs DNA damage caused by endogenous and chemotherapy-induced DNA crosslinks, and responds to replication stress1,2. Genetic inactivation of this pathway by mutation of genes encoding FA complementation group (FANC