Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Sarah L Mackie"'
Autor:
Wolfgang A. Schmidt, Bhaskar Dasgupta, Jennifer Sloane, Angeliki Giannelou, Yuqing Xu, Sebastian H. Unizony, Sarah L. Mackie, Miguel A. Gonzalez-Gay, Robert Spiera, Kenneth J. Warrington, Peter M. Villiger, Michael C. Nivens, Bolanle Akinlade, Yong Lin, Frank Buttgereit, John H. Stone
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-16 (2023)
Abstract Background Giant cell arteritis (GCA) is primarily treated with glucocorticoids (GCs), which have substantial toxicity. Tocilizumab, an interleukin-6-receptor inhibitor (IL-6Ri), showed beneficial effects in GCA, leading to its approval. Thi
Externí odkaz:
https://doaj.org/article/4519641ec60d4627b6d5c6d36c1bb6ac
Autor:
Dawn L Cooper, Stephen G Martin, James I Robinson, Sarah L Mackie, Christopher J Charles, Jackie Nam, YEAR Consortium, John D Isaacs, Paul Emery, Ann W Morgan
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e28918 (2012)
ObjectiveThe expression of FcγRIIIa/CD16 may render monocytes targets for activation by IgG-containing immune complexes (IC). We investigated whether FcγRIIIa/CD16 was upregulated in rheumatoid arthritis (RA), associated with TNF production in resp
Externí odkaz:
https://doaj.org/article/7dfe4c7e8db24f158c23d451fe0c074d
Autor:
Lisa M. Duff, Andrew F. Scarsbrook, Nishant Ravikumar, Russell Frood, Gijs D. van Praagh, Sarah L. Mackie, Marc A. Bailey, Jason M. Tarkin, Justin C. Mason, Kornelis S. M. van der Geest, Riemer H. J. A. Slart, Ann W. Morgan, Charalampos Tsoumpas
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 343 (2023)
The aim of this study was to develop and validate an automated pipeline that could assist the diagnosis of active aortitis using radiomic imaging biomarkers derived from [18F]-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography (FDG P
Externí odkaz:
https://doaj.org/article/7d7a3b735b86439e87f00a13c1d8467f
Autor:
Tiara Gill, Michael Putman, Sebastian E Sattui, Shahir Hamdulay, Richard Conway, David F L Liew, Aman Sharma, John H Stone, Sarah L Mackie, Puja Mehta
Publikováno v:
The Lancet Rheumatology. 5:e175-e177
Autor:
Diogo Esperança Almeida, Kate Smith, Borsha A Sarker, Andrew Barr, Richard J Wakefield, Sarah L Mackie
Publikováno v:
Rheumatology.
Objectives To determine whether the halo count (HC) on temporal and axillary artery US (TAUS) predicts time to relapse in giant cell arteritis (GCA). Methods We conducted a single-centre retrospective study of GCA patients. HC, the number of vessels
Autor:
Joyce Lim, Emma Dures, Lawrence Bailey, Celia Almeida, Carlee Ruediger, Catherine Hill, Joanna Robson, Sarah L Mackie
Publikováno v:
Rheumatology. 62
Background/Aims Recognition of jaw claudication is crucial to expedite diagnosis and treatment of giant cell arteritis (GCA). The ACR 1990 criteria defined claudication of the jaw, tongue or deglutition as “development or worsening of fatigue or di
Autor:
Susan Bridgewater, Mwidimi Ndosi, Jill Dawson, Pamela Richards, Christine Silverthorne, Emma Dures, Susan Goodman, Catherine Hill, Sarah L Mackie, Joanna C Robson
Publikováno v:
Rheumatology. 62
Background/Aims Systemic glucocorticoids are key in the management of life- and organ-threatening rheumatic diseases, but have wide-ranging adverse effects of concern to patients and clinicians. We aimed to validate a Patient Reported Outcome (PRO) m
Autor:
Daniel Maunder, Philip M Brown, Ben Barron-Millar, Dennis Lendrem, Najib Naamane, Jamie Macdonald, Xiao Wang, Amy E Anderson, Ann W Morgan, Sarah L Mackie, Rachel Crossland, Arthur G Pratt
Publikováno v:
Rheumatology. 62
Background/Aims Early diagnosis and prompt and effective intervention for people with immune-mediated inflammatory diseases (IMIDs) such as rheumatoid arthritis (RA) improves outcomes. Non-invasive biomarkers that reflect unique aspects of underlying
Autor:
Nishita Padmanabhan, Sara Muller, James Bailey, Toby Helliwell, Sarah L Mackie, Christian D Mallen, Edward Roddy
Publikováno v:
Rheumatology. 62
Background/Aims Giant cell arteritis (GCA) is considered a medical emergency, and relapses are common, affecting around 50% of patients. Many of the early symptoms of GCA are non-specific and highly prevalent in older people, making the diagnosis cha
Autor:
Funmi Morgan, Hussain Al-Hilali, Margaret Grover, Lorna Neill, Eleanor Snowden, Jean Scopes, George Crowther, Amy Rebane, Hanif Ismail, Sarah L Mackie
Publikováno v:
Rheumatology. 62
Background/Aims Glucocorticoid toxicities are well-known, but patient involvement work (PMR Voices 2021) had highlighted a need for better patient education/counselling about side-effects, including early neuropsychiatric toxicity, and support for se