Výsledky vyhledávání - "Sarah L Henkle"

Akademický článek

Mesenchymal stem cell 1 (MSC1)-based therapy attenuates tumor growth whereas MSC2-treatment promotes tumor growth and metastasis.

Autor: Ruth S Waterman, Sarah L Henkle, Aline M Betancourt

Publikováno v: PLoS ONE, Vol 7, Iss 9, p e45590 (2012)

Currently, there are many promising clinical trials using mesenchymal stem cells (MSCs) in cell-based therapies of numerous diseases. Increasingly, however, there is a concern over the use of MSCs because they home to tumors and can support tumor gro

Externí odkaz: https://doaj.org/article/024f9d6e5e7544229985ecf223e1ce10

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Akademický článek

Toll-like receptor 3 and suppressor of cytokine signaling proteins regulate CXCR4 and CXCR7 expression in bone marrow-derived human multipotent stromal cells.

Autor: Suzanne L Tomchuck, Sarah L Henkle, Seth B Coffelt, Aline M Betancourt

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e39592 (2012)

BACKGROUND:The use of bone marrow-derived human multipotent stromal cells (hMSC) in cell-based therapies has dramatically increased in recent years, as researchers have exploited the ability of these cells to migrate to sites of tissue injury, inflam

Externí odkaz: https://doaj.org/article/a2e82ba0149445dea129945470065c61

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Akademický článek

A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype.

Autor: Ruth S Waterman, Suzanne L Tomchuck, Sarah L Henkle, Aline M Betancourt

Publikováno v: PLoS ONE, Vol 5, Iss 4, p e10088 (2010)

Our laboratory and others reported that the stimulation of specific Toll-like receptors (TLRs) affects the immune modulating responses of human multipotent mesenchymal stromal cells (hMSCs). Toll-like receptors recognize "danger" signals, and their a

Externí odkaz: https://doaj.org/article/452cd3d69af8428795acb46dec7f3a7b

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Toll-like receptor 3 and suppressor of cytokine signaling proteins regulate CXCR4 and CXCR7 expression in bone marrow-derived human multipotent stromal cells

Autor: Sarah L. Henkle, Aline M. Betancourt, Suzanne L. Tomchuck, Seth B. Coffelt

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e39592 (2012)
PLoS ONE

Background The use of bone marrow-derived human multipotent stromal cells (hMSC) in cell-based therapies has dramatically increased in recent years, as researchers have exploited the ability of these cells to migrate to sites of tissue injury, inflam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6fd0b8a3cb6f2f9a85ea98d2410bd3
http://europepmc.org/articles/PMC3382127?pdf=render

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The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells

Autor: Jennifer L. Dembinski, Sarah L. Henkle, Kerstin Höner zu Bentrup, Aline B. Scandurro, Kevin J. Zwezdaryk, Suzanne L. Tomchuck, Seth B. Coffelt, Frank C. Marini, Elizabeth S. Danka, Keri Watson, Heather L. LaMarca

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 106(10)

Bone marrow-derived mesenchymal stem cells or multipotent mesenchymal stromal cells (MSCs) have been shown to engraft into the stroma of several tumor types, where they contribute to tumor progression and metastasis. However, the chemotactic signals

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a9fa38c580df3d091960893d471ab0
https://pubmed.ncbi.nlm.nih.gov/19234121

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