Deep sequencing of RNA from ancient maize kernels.

Autor: Sarah L Fordyce, Maria C Ávila-Arcos, Morten Rasmussen, Enrico Cappellini, J Alberto Romero-Navarro, Nathan Wales, David E Alquezar-Planas, Steven Penfield, Terence A Brown, Jean-Philippe Vielle-Calzada, Rafael Montiel, Tina Jørgensen, Nancy Odegaard, Michael Jacobs, Bernardo Arriaza, Thomas F G Higham, Christopher Bronk Ramsey, Eske Willerslev, M Thomas P Gilbert

Publikováno v: PLoS ONE, Vol 8, Iss 1, p e50961 (2013)

The characterization of biomolecules from ancient samples can shed otherwise unobtainable insights into the past. Despite the fundamental role of transcriptomal change in evolution, the potential of ancient RNA remains unexploited - perhaps due to do

Externí odkaz: https://doaj.org/article/b0b48a9c0776467e9bac0e115d298efc

Increased p53 signaling impairs neural differentiation in HUWE1-promoted intellectual disabilities

Autor: Rossana Aprigliano, Merdane Ezgi Aksu, Stefano Bradamante, Boris Mihaljevic, Wei Wang, Kristin Rian, Nicola P. Montaldo, Kayla Mae Grooms, Sarah L. Fordyce Martin, Diana L. Bordin, Matthias Bosshard, Yunhui Peng, Emil Alexov, Cindy Skinner, Nina-Beate Liabakk, Gareth J. Sullivan, Magnar Bjørås, Charles E. Schwartz, Barbara van Loon

Publikováno v: Cell Reports Medicine, Vol 2, Iss 4, Pp 100240- (2021)

Summary: Essential E3 ubiquitin ligase HUWE1 (HECT, UBA, and WWE domain containing 1) regulates key factors, such as p53. Although mutations in HUWE1 cause heterogenous neurodevelopmental X-linked intellectual disabilities (XLIDs), the disease mechan

Externí odkaz: https://doaj.org/article/b8557ff56ac14f5fb273cea9a18c581c

Population genetics of Anopheles koliensis through Papua New Guinea: New cryptic species and landscape topography effects on genetic connectivity

Autor: Luke Ambrose, Sarah L. Fordyce, Nigel W. Beebe, Robert D. Cooper, Jeffrey O. Hanson, Weixin Xu, Cynthia Riginos

Publikováno v: Ecology and Evolution, Vol 9, Iss 23, Pp 13375-13388 (2019)
Ambrose, L, Hanson, J O, Riginos, C, Xu, W, Fordyce, S, Cooper, R D & Beebe, N W 2019, ' Population genetics of Anopheles koliensis through Papua New Guinea : New cryptic species and landscape topography effects on genetic connectivity ', Ecology and Evolution, vol. 9, no. 23, pp. 13375-13388 . https://doi.org/10.1002/ece3.5792
Ecology and Evolution

New Guinea is a topographically and biogeographically complex region that supports unique endemic fauna. Studies describing the population connectivity of species through this region are scarce. We present a population and landscape genetic study on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fe8addbb23d70325dd2376df1da25d
https://doaj.org/article/c3d189bea5b54adba0b0b225a89b69d3

Runs of homozygosity in killer whale genomes provide a global record of demographic histories

Autor: Kelly M. Robertson, Rebecca Hooper, Rochelle Constantine, Renaud de Stephanis, Sara Tavares, Alana Alexander, Guangyi Fan, John A. Totterdell, Ruth Esteban, Nicholas J. Davison, Tim Gerrodette, Lisa T. Ballance, John W. Durban, Songhai Li, Paul Tixier, Phillip A. Morin, Michael D. Martin, C. S. Baker, Sarah L. Fordyce Martin, Robin W. Baird, Jay Barlow, Luciano Dalla Rosa, Filipa I. P. Samarra, Andrew Brownlow, Tim Collins, Laurent Excoffier, Andrew D. Foote, M. Bradley Hanson, Jochen B. W. Wolf, M. Thomas P. Gilbert, Karin A. Forney, Christophe Guinet, Paul R. Wade, Yaolei Zhang

Publikováno v: Molecular Ecology (0962-1083) (Wiley), 2021-12, Vol. 30, N. 23, P. 6162-6177
Foote, A D, Hooper, R, Alexander, A, Baird, R W, Baker, C S, Ballance, L, Barlow, J, Brownlow, A, Collins, T, Constantine, R, Dalla Rosa, L, Davison, N J, Durban, J W, Esteban, R, Excoffier, L, Fordyce Martin, S L, Forney, K A, Gerrodette, T, Gilbert, M T P, Guinet, C, Hanson, M B, Li, S, Martin, M D, Robertson, K M, Samarra, F I P, de Stephanis, R, Tavares, S B, Tixier, P, Totterdell, J A, Wade, P, Wolf, J B W, Fan, G, Zhang, Y & Morin, P A 2021, ' Runs of homozygosity in killer whale genomes provide a global record of demographic histories ', Molecular Ecology, vol. 30, no. 23, pp. 6162-6177 . https://doi.org/10.1111/mec.16137
Molecular Ecology
Foote, Andrew D.; Hooper, Rebecca; Alexander, Alana; Baird, Robin W.; Baker, Charles Scott; Ballance, Lisa; Barlow, Jay; Brownlow, Andrew; Collins, Tim; Constantine, Rochelle; Dalla Rosa, Luciano; Davison, Nicholas J.; Durban, John W.; Esteban, Ruth; Excoffier, Laurent; Fordyce Martin, Sarah L.; Forney, Karin A.; Gerrodette, Tim; Gilbert, M. Thomas P.; Guinet, Christophe; ... (2021). Runs of homozygosity in killer whale genomes provide a global record of demographic histories. Molecular Ecology, 30(23), pp. 6162-6177. Wiley-Blackwell 10.1111/mec.16137
Molecular Ecology, 2021, 30, pp.6162-6177. ⟨10.1111/mec.16137⟩
Molecular Ecology, Wiley, 2021, ⟨10.1111/mec.16137⟩
Foote, A D, Hooper, R, Alexander, A, Baird, R W, Baker, C S, Ballance, L, Barlow, J, Brownlow, A, Collins, T, Constantine, R, Dalla Rosa, L, Davison, N J, Durban, J W, Esteban, R, Excoffier, L, Martin, S L F, Forney, K A, Gerrodette, T, Gilbert, M T P, Guinet, C, Hanson, M B, Li, S, Martin, M D, Robertson, K M, Samarra, F I P, de Stephanis, R, Tavares, S B, Tixier, P, Totterdell, J A, Wade, P, Wolf, J B W, Fan, G, Zhang, Y & Morin, P A 2021, ' Runs of homozygosity in killer whale genomes provide a global record of demographic histories ', Molecular Ecology, vol. 30, no. 23, pp. 6162-6177 . https://doi.org/10.1111/mec.16137

International audience; Runs of homozygosity (ROH) occur when offspring inherit haplotypes that are identical by descent from each parent. Length distributions of ROH are informative about population history; specifically, the probability of inbreedi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::babc6dbefac028fcbf455e942059f6fb
https://pubmed.ncbi.nlm.nih.gov/34416064

Increased p53 signaling impairs neural differentiation causing HUWE1-promoted intellectual disabilities

Autor: Rossana Aprigliano, Stefano Bradamante, Boris Mihaljevic, Wei Wang, Sarah L. Fordyce Martin, Diana L. Bordin, Matthias Bosshard, Nicola P. Montaldo, Yunhui Peng, Emil Alexov, Cindy Skinner, Nina-Beate Liabakk, Magnar Bjørås, Charles E. Schwartz, Barbara van Loon

SUMMARYEssential E3 ubiquitin ligase HUWE1 (HECT, UBA and WWE domain containing 1) regulates key factors, as p53. Mutations in HUWE1 have been associated with neurodevelopmental X-linked intellectual disabilities (XLIDs), however the pathomechanism a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a6c31003adc04e99f6de765ba0c8f0
https://doi.org/10.1101/2020.05.10.087296