Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Sarah L Dallas"'
Autor:
Matthew Prideaux, Sarah L Dallas, Ning Zhao, Erica D Johnsrud, Patricia A Veno, Dayong Guo, Yuji Mishina, Stephen E Harris, Lynda F Bonewald
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125731 (2015)
Parathyroid Hormone (PTH) can exert both anabolic and catabolic effects on the skeleton, potentially through expression of the PTH type1 receptor (PTH1R), which is highly expressed in osteocytes. To determine the cellular and molecular mechanisms res
Externí odkaz:
https://doaj.org/article/15c0fa0d8a314063a138ede1478f4633
Autor:
Filipa C. Simões, Thomas J. Cahill, Amy Kenyon, Daria Gavriouchkina, Joaquim M. Vieira, Xin Sun, Daniela Pezzolla, Christophe Ravaud, Eva Masmanian, Michael Weinberger, Sarah Mayes, Madeleine E. Lemieux, Damien N. Barnette, Mala Gunadasa-Rohling, Ruth M. Williams, David R. Greaves, Le A. Trinh, Scott E. Fraser, Sarah L. Dallas, Robin P. Choudhury, Tatjana Sauka-Spengler, Paul R. Riley
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Macrophages mediate the fibrotic response after a heart attack by extracellular matrix turnover and cardiac fibroblasts activation. Here the authors identify an evolutionarily-conserved function of macrophages that contributes directly to the forming
Externí odkaz:
https://doaj.org/article/edf55153a7b34a528c084339f4ceeac3
Autor:
Yukiko, Kitase, Julian A, Vallejo, Sarah L, Dallas, Yixia, Xie, Mark, Dallas, LeAnn, Tiede-Lewis, David, Moore, Anthony, Meljanac, Corrine, Kumar, Carrie, Zhao, Jennifer, Rosser, Marco, Brotto, Mark L, Johnson, Ziyue, Liu, Michael J, Wacker, Lynda, Bonewald
Publikováno v:
Aging. 15:308-352
Frailty is the hallmark of aging that can be delayed with exercise. The present studies were initiated based on the hypothesis that long-term voluntary wheel running (VWR) in female mice from 12 to 18 or 22 months of age would have beneficial effects
Autor:
Sarah L. Dallas, Weiping Qin
Publikováno v:
Curr Osteoporos Rep
(a). PURPOSE: Extracellular vesicles (EV), which include exosomes and microvesicles, are membrane-bound particles shed by most cell types and are important mediators of cell-cell communication by delivering their cargo of proteins, miRNA and mRNA to
Autor:
Sarah L. Dallas, Michael J. Wacker, Leticia Brotto, Kun Wang, Lora A. Shiflett, Lynda F. Bonewald, Jian Huang, Marco Brotto
Publikováno v:
Cell Cycle
Osteoporosis and sarcopenia (osteosarcopenia (OS)) are twin-aging diseases. The biochemical crosstalk between muscle and bone seems to play a role in OS. We have previously shown that osteocytes produce soluble factors with beneficial effects on musc
Autor:
Yukiko Kitase, Tsutomu Matsumoto, Delphine B. Maurel, Mark L. Johnson, Marie A. Harris, Sarah L. Dallas, Julian Vallejo, Stephen E. Harris, Lynda F. Bonewald, Marco Brotto, Michael J. Wacker
Publikováno v:
Bone Research, Vol 7, Iss 1, Pp 1-13 (2019)
Transgenic mice are widely used to delete or overexpress genes in a cell specific manner to advance knowledge of bone biology, function and disease. While numerous Cre models exist to target gene recombination in osteoblasts and osteoclasts, few targ
Publikováno v:
Methods in Molecular Biology ISBN: 9781071610275
Methods Mol Biol
Methods Mol Biol
Recent advances have revived interest in the concept of osteocyte perilacunar/canalicular remodeling (PLR) and have motivated efforts to identify the mechanisms regulating this process in bone in the context of normal physiology and pathological cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6fc47ddbbd67eaefd53ccd0bbffc06e
https://doi.org/10.1007/978-1-0716-1028-2_17
https://doi.org/10.1007/978-1-0716-1028-2_17
Autor:
Sarah L. Dallas, Thiagarajan Ganesh, Loretta E. Laughrey, LeAnn M. Tiede-Lewis, Sravan K. Kola, Mark T. Begonia, Mark L. Johnson
Publikováno v:
Bone Reports, Vol 12, Iss, Pp 100277-(2020)
Bone Reports
Bone Reports
Osteocytes are thought to be the primary mechanosensory cells within bone, regulating both osteoclasts and osteoblasts to control load induced changes in bone resorption and formation. Osteocytes initiate intracellular responses including activating
Autor:
Ritwik Datta, Michael J Podolsky, Sarah L. Dallas, Claude Jourdan Le Saux, Paul J. Wolters, Steven K. Huang, Christopher D Yang, Kamran Atabai, Carlos Lizama Valenzuela, Stephen L. Nishimura
Publikováno v:
JCI Insight
JCI insight, vol 5, iss 10
JCI insight, vol 5, iss 10
Although aging represents the most important epidemiologic risk factor for fibrotic disease, the reasons for this are incompletely understood. Excess collagen deposition in tissues is the sine qua non of tissue fibrosis and can be viewed as an imbala
Autor:
Michael Weinberger, Daniela Pezzolla, Filipa C. Simões, Scott E. Fraser, Mala Gunadasa-Rohling, Damien N. Barnette, Eva Masmanian, Ruth M. Williams, Sarah Mayes, Thomas J. Cahill, Robin P. Choudhury, Sarah L. Dallas, Le A. Trinh, Christophe Ravaud, Joaquim M. Vieira, Daria Gavriouchkina, Tatjana Sauka-Spengler, Paul R. Riley, Xin Sun, Amy Kenyon, Madeleine E. Lemieux, David R. Greaves
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Canonical roles for macrophages in mediating the fibrotic response after a heart attack include extracellular matrix turnover and activation of cardiac fibroblasts to initiate collagen deposition. Here we reveal that macrophages directly contribute c