Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Sarah L, Miles"'
Autor:
Kathleen C. Brown, Kushal J. Modi, Reagan S. Light, Ashley J. Cox, Timothy E. Long, Rama S. Gadepalli, John M. Rimoldi, Sarah L. Miles, Gary Rankin, Monica Valentovic, Krista L. Denning, Maria T. Tirona, Paul T. Finch, Joshua A. Hess, Piyali Dasgupta
Publikováno v:
Journal of Medicinal Chemistry. 66:4294-4323
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32a804c7c1f00bc606e3d8948614846d
https://doi.org/10.1021/acs.jmedchem.2c01594
https://doi.org/10.1021/acs.jmedchem.2c01594
Autor:
Jamie R. Friedman, Stephen D. Richbart, Justin C. Merritt, Kathleen C. Brown, Krista L. Denning, Maria T. Tirona, Monica A. Valentovic, Sarah L. Miles, Piyali Dasgupta
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 118, Iss , Pp - (2019)
Cancer progression is a complex multistep process comprising of angiogenesis of the primary tumor, its invasion into the surrounding stroma and its migration to distant organs to produce metastases. Nutritional compounds of the “capsaicinoid” fam
Externí odkaz:
https://doaj.org/article/692173106ad64abe9c59da76c343c209
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 5022 (2021)
Ovarian cancer is a fatal gynecological cancer because of a lack of early diagnosis, which often relapses as chemoresistant. Trichodermin, a trichothecene first isolated from Trichoderma viride, is an inhibitor of eukaryotic protein synthesis. Howeve
Externí odkaz:
https://doaj.org/article/93ddb02051ac4956a2d936cd09ef6106
Autor:
Piyali Dasgupta, Stephen D. Richbart, Austin T. Akers, Jamie R. Friedman, Sarah L. Miles, Eric W. Bow, John M. Rimoldi, Yi Charlie Chen
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2e7d4dc5014d68ead36c2657d2815c1
https://doi.org/10.1096/fasebj.2022.36.s1.l6388
https://doi.org/10.1096/fasebj.2022.36.s1.l6388
Autor:
Emily G. Moles, Jamie R. Friedman, Sarah L. Miles, Kathleen C. Brown, Kelly J. Hopper, Yi Charlie Chen, Piyali Dasgupta
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f61e55344819fd8f4ea6c4d1799882b
https://doi.org/10.1096/fasebj.2022.36.s1.l6394
https://doi.org/10.1096/fasebj.2022.36.s1.l6394
Autor:
Justin C. Merritt, Stephen D. Richbart, Emily G. Moles, Ashley J. Cox, Kathleen C. Brown, Sarah L. Miles, Paul T. Finch, Joshua A. Hess, Maria T. Tirona, Monica A. Valentovic, Piyali Dasgupta
Publikováno v:
Pharmacologytherapeutics. 238
Capsaicin (trans-8-methyl-N-vanillyl-6-noneamide) is a hydrophobic, lipophilic vanilloid phytochemical abundantly found in chili peppers and pepper extracts. Several convergent studies show that capsaicin displays robust cancer activity, suppressing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc92bba69fa9fed1497aef647988719
https://pubmed.ncbi.nlm.nih.gov/35351463
https://pubmed.ncbi.nlm.nih.gov/35351463
Autor:
Stephen D Richbart, Piyali Dasgupta, Jamie K. Lau, Sarah L. Miles, Kathleen C. Brown, Nicholas A. Nolan, Jamie R. Friedman, Justin C Merritt, Austin T. Akers, Zachary R. Robateau
Publikováno v:
Pharmacology & Therapeutics. 194:222-254
The neurotransmitter acetylcholine (ACh) acts as an autocrine growth factor for human lung cancer. Several lines of evidence show that lung cancer cells express all of the proteins required for the uptake of choline (choline transporter 1, choline tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd78ede5b163a5deb7ca76c6655d5b8
https://doi.org/10.1016/j.pharmthera.2018.10.002
https://doi.org/10.1016/j.pharmthera.2018.10.002
Autor:
Gary O. Rankin, Yi Charlie Chen, Piyali Dasgupta, Stephen J. Cutler, Sarah L. Miles, Ying Gao
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 5022, p 5022 (2021)
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 5022, p 5022 (2021)
Ovarian cancer is a fatal gynecological cancer because of a lack of early diagnosis, which often relapses as chemoresistant. Trichodermin, a trichothecene first isolated from Trichoderma viride, is an inhibitor of eukaryotic protein synthesis. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e94a70383b4bf125b8880661b323833
Autor:
Yi Charlie Chen, Austin T. Akers, Eric W. Bow, Krista L. Denning, Kathleen C. Brown, Piyali Dasgupta, Stephen D Richbart, Jamie R. Friedman, John M. Rimoldi, Nicholas A. Nolan, Sarah L. Miles
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdde525bf3d68c12ef92758b3930ba6d
https://doi.org/10.1096/fasebj.2021.35.s1.00366
https://doi.org/10.1096/fasebj.2021.35.s1.00366
Autor:
Gary O. Rankin, Joshua A. Hess, Rama S.V. Gadepalli, Monica A. Valentovic, Sarah L. Miles, Paul T Finch, John M. Rimoldi, Maria Tria Tirona, Kathleen C. Brown, Jamie R Friedman, Piyali Dasgupta, Stephen D Richbart
Publikováno v:
Journal of medicinal chemistry. 64(3)
Capsaicin displays robust growth-inhibitory activity in multiple human cancers. However, the feasibility of capsaicin as a clinically relevant anticancer drug is hampered by its adverse side effects. This concern has led to extensive research focused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec177064c5870b5f339ab64903374b0
https://pubmed.ncbi.nlm.nih.gov/33508189
https://pubmed.ncbi.nlm.nih.gov/33508189