Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sarah L, Etheridge"'
Autor:
Lele Song, Sarah L. Etheridge, Owen T. Jones, Italo A. Espinoza-Fuenzalida, Elizabeth M. Fitzgerald
Publikováno v:
Current Molecular Pharmacology. 8:169-179
Voltage-gated calcium channels (Cav) and their associated proteins are pivotal signalling complexes in excitable cell physiology. In nerves and muscle, Cav tailor calcium influx to processes including neurotransmission, muscle contraction and gene ex
Autor:
Sarah L. Etheridge, Paul Armenise, Philip Robinson, Elizabeth M. Fitzgerald, Lele Song, Owen T. Jones
Publikováno v:
Cell Calcium. 48:183-194
Voltage-gated calcium channels (Ca(v)s) comprise a pore-forming α₁ with auxiliary α₂δ and β subunits which modulate Ca(v) function and surface expression. Ca(v)α₁ and α₂δ are present in signalling complexes termed lipid rafts but it is
Publikováno v:
British Journal of Pharmacology. 158:848-861
Background and purpose: Blood vessel culture is gaining interest for use with transfection-based techniques, but alters the contractile properties of the vessels. The present study tested the effects of culture on the intrinsic tone of rat pulmonary
Publikováno v:
Cell communicationadhesion. 21(3)
The importance of desmosomes in tissue homeostasis is highlighted by natural and engineered mutations in desmosomal genes, which compromise the skin or heart and in some instances both. Desmosomal gene mutations account for 45-50% of cases of arrhyth
Autor:
Akemi Ishida-Yamamoto, Edel A. O'Toole, Sarah L. Etheridge, Nihal Kaplan, Matthew A. Brooke, Spiro Getsios, Charlotte Simpson, David P. Kelsell, Olivier Marchès
Publikováno v:
Human molecular genetics. 23(15)
iRHOM2 is a highly conserved, catalytically inactive member of the Rhomboid family, which has recently been shown to regulate the maturation of the multi-substrate ectodomain sheddase enzyme ADAM17 (TACE) in macrophages. Dominant iRHOM2 mutations are
Autor:
Irene M. Leigh, Anthony Ellis, Vincent Plagnol, D. Timothy Bishop, Nigel K. Spurr, Diana C. Blaydon, Fiona E. McRonald, Janet M. Risk, Rebecca Carroll, Andrew P. South, Howard P. Stevens, Sarah L. Etheridge, John K. Field, Janusz Jankowski, Hans Christian Hennies, David P. Kelsell
Tylosis esophageal cancer (TOC) is an autosomal-dominant syndrome characterized by palmoplantar keratoderma, oral precursor lesions, and a high lifetime risk of esophageal cancer. We have previously localized the TOC locus to a small genomic interval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8a44d2ab14f2800e0368da0941b930
https://europepmc.org/articles/PMC3276661/
https://europepmc.org/articles/PMC3276661/
Autor:
Philip Robinson, Elizabeth M. Fitzgerald, Riddhi Shah, Lele Song, Sarah L. Etheridge, Owen T. Jones
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 6, p e19802 (2011)
PLoS ONE, Vol 6, Iss 6, p e19802 (2011)
Voltage-gated calcium channels (Ca(v)) exist as heteromultimers comprising a pore-forming α(1) with accessory β and α(2)δ subunits which modify channel trafficking and function. We previously showed that α(2)δ-1 (and likely the other mammalian
Publikováno v:
British journal of pharmacology. 158(3)
Blood vessel culture is gaining interest for use with transfection-based techniques, but alters the contractile properties of the vessels. The present study tested the effects of culture on the intrinsic tone of rat pulmonary arteries (PAs) and exami