Zobrazeno 1 - 10 of 28 pro vyhledávání: '"Sarah Kathleen Haas Lockie"'
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AgRP Neurons Require Carnitine Acetyltransferase to Regulate Metabolic Flexibility and Peripheral Nutrient Partitioning
Autor: Brian J. Oldfield, Mathieu Méquinion, Cheng Huang, Sarah Kathleen Haas Lockie, Raphael Denis, Zane B. Andrews, Rachel E. Clarke, Ralf B. Schittenhelm, Grzegorz M Kowalski, Matthew J. Watt, Romana Stark, Serge Luquet, Jeferson F. Goularte, Alexander Reichenbach, Clinton R. Bruce, Randall L. Mynatt, Moyra B Lemus
Publikováno v: Cell Reports, Vol 22, Iss 7, Pp 1745-1759 (2018)
Cell Reports
Cell Reports, Elsevier Inc, 2018, 22 (7), pp.1745-1759. ⟨10.1016/j.celrep.2018.01.067⟩
Cell Reports, 2018, 22 (7), pp.1745-1759. ⟨10.1016/j.celrep.2018.01.067⟩
International audience; AgRP neurons control peripheral substrate utilization and nutrient partitioning during conditions of energy deficit and nutrient replenishment, although the molecular mechanism is unknown. We examined whether carnitine acetylt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8e5a566cfc1878c4f06d3dbd301f54
http://www.sciencedirect.com/science/article/pii/S2211124718301165
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3
Glucose Availability Predicts the Feeding Response to Ghrelin in Male Mice, an Effect Dependent on AMPK in AgRP Neurons
Autor: Zane B. Andrews, Mathieu Méquinion, Romana Stark, David Spanswick, Sarah S Ch'ng, Dong Kong, Sarah Kathleen Haas Lockie, Andrew J Lawrence
Metabolic feedback from the periphery to the brain results from a dynamic physiologic fluctuation of nutrients and hormones, including glucose and fatty acids, ghrelin, leptin, and insulin. The specific interactions between humoral factors and how th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e7c00f3901d57aac256eae02727650
https://europepmc.org/articles/PMC6169619/
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4
Carnitine Acetyltransferase in AgRP Neurons Is Required for the Homeostatic Adaptation to Restricted Feeding in Male Mice
Autor: Zane B. Andrews, Sarah Kathleen Haas Lockie, Randall L. Mynatt, Mathieu Méquinion, Alexander Reichenbach, Romana Stark, Moyra B Lemus, Jacqueline Bayliss
Publikováno v: Endocrinology. 159(6)
Behavioral adaptation to periods of varying food availability is crucial for survival, and agouti-related protein (AgRP) neurons have been associated with entrainment to temporal restricted feeding. We have shown that carnitine acetyltransferase (Cra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c6033ae8b22a46acf2c53b76b59562
https://pubmed.ncbi.nlm.nih.gov/29697769
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5
Food Seeking in a Risky Environment: A Method for Evaluating Risk and Reward Value in Food Seeking and Consumption in Mice
Autor: Sasha Rawlinson, Natalie Guiney, Clare V. McAuley, Zane B. Andrews, Sarah Kathleen Haas Lockie
Publikováno v: Frontiers in Neuroscience
Most studies that measure food intake in mice do so in the home cage environment. This necessarily means that mice do not engage in food seeking before consumption, a behaviour that is ubiquitous in free-living animals. We modified and validated seve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc43827dba0540e2734771ee07c749f0
http://europepmc.org/articles/PMC5276994
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6
The Temporal Pattern of cfos Activation in Hypothalamic, Cortical, and Brainstem Nuclei in Response to Fasting and Refeeding in Male Mice
Autor: Moyra B Lemus, Sarah Kathleen Haas Lockie, Jacqueline Bayliss, Zane B. Andrews, Alexander Reichenbach, Qunli Wu, Romana Stark
Publikováno v: Endocrinology. 155:840-853
In this study we examined fasted and refed cfos activation in cortical, brainstem, and hypothalamic brain regions associated with appetite regulation. We examined a number of time points during refeeding to gain insight into the temporal pattern of n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99402a599cd29c6da7e005ebec51186f
https://doi.org/10.1210/en.2013-1831
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7
The hormonal signature of energy deficit: Increasing the value of food reward
Autor: Sarah Kathleen Haas Lockie, Zane B. Andrews
Publikováno v: Molecular Metabolism. 2(4):329-336
Energy deficit is characterised by high ghrelin levels, and low leptin and insulin levels and we suggest that this provides a metabolic signature sensed by the brain to increase motivated behaviour to obtain food. We believe that the hormonal profile
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c860943bc0335c53faf66b721967253e
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8
Brown adipose tissue thermogenesis in the resistance to and reversal of obesity
Autor: Sarah Kathleen Haas Lockie, Diego Perez-Tilve, Aneta Stefanidis, Brian J. Oldfield
Publikováno v: Adipocyte. 2:196-200
The capacity for increased thermogenesis through brown adipose tissue (BAT) activation is important for body weight homeostasis. Differences in BAT thermogenesis can underlie significant differences in body weight and body composition, as we demonstr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31a190c4e8df1822550ffb1d5cfed34b
https://doi.org/10.4161/adip.25417
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9
Des-Acyl Ghrelin and Ghrelin O-Acyltransferase Regulate Hypothalamic-Pituitary-Adrenal Axis Activation and Anxiety in Response to Acute Stress
Autor: Sarah J. Spencer, Sarah Kathleen Haas Lockie, Tamas Kozicz, Jacqueline Bayliss, Alexander Reichenbach, Romana Stark, Agustina Cabral, Mario Perello, Moyra B Lemus, Tara Dinan, Vanessa V. Santos, Zane B. Andrews, Bram Geenen
Publikováno v: Endocrinology, 157, 3946-3957
Endocrinology, 157, 10, pp. 3946-3957
Ghrelin exists in two forms in circulation, acyl ghrelin and des-acyl ghrelin, both of which have distinct and fundamental roles in a variety of physiological functions. Despite this fact, a large proportion of papers simply measure and refer to plas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440a71444ea27b8a10960473d5102f40
http://hdl.handle.net/2066/167714
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10
Direct Control of Brown Adipose Tissue Thermogenesis by Central Nervous System Glucagon-Like Peptide-1 Receptor Signaling
Autor: Joseph Chabenne, Daniel J. Drucker, Christelle Veyrat-Durebex, Kristy M. Heppner, Diego Perez-Tilve, Françoise Rohner-Jeanrenaud, Matthias H. Tschöp, Richard D. DiMarchi, Sarah Kathleen Haas Lockie, Gayathri Ananthakrishnan, Donald A. Morgan, Nilika Chaudhary, Brian J. Oldfield, Kamal Rahmouni
Publikováno v: Diabetes
Diabetes, Vol. 61, No 11 (2012) pp. 2753-62
We studied interscapular brown adipose tissue (iBAT) activity in wild-type (WT) and glucagon-like peptide 1 receptor (GLP-1R)–deficient mice after the administration of the proglucagon-derived peptides (PGDPs) glucagon-like peptide (GLP-1), glucago
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786d7cfecf6f8bb3e1eeee818df8031a
http://europepmc.org/articles/PMC3478556
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