Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Sarah K. Sasse"'
Autor:
Serge Campeau, Connor McNulty, Jacob T. Stanley, Anthony N. Gerber, Sarah K. Sasse, Robin D. Dowell
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Chronic stress is epidemiologically correlated with physical and psychiatric disorders. Whereas many animal models of chronic stress induce symptoms of psychopathology, repeated homotypic stressors to moderate intensity stimuli typically reduce stres
Externí odkaz:
https://doaj.org/article/8032d76b380d4d2093d5837009267aa7
Autor:
Fabienne Gally, Sarah K. Sasse, Jonathan S. Kurche, Margaret A. Gruca, Jonathan H. Cardwell, Tsukasa Okamoto, Hong W. Chu, Xiaomeng Hou, Olivier B. Poirion, Justin Buchanan, Sebastian Preissl, Bing Ren, Sean P. Colgan, Robin D. Dowell, Ivana V. Yang, David A. Schwartz, Anthony N. Gerber
Publikováno v:
JCI Insight, Vol 6, Iss 2 (2021)
The G/T transversion rs35705950, located approximately 3 kb upstream of the MUC5B start site, is the cardinal risk factor for idiopathic pulmonary fibrosis (IPF). Here, we investigate the function and chromatin structure of this –3 kb region and pr
Externí odkaz:
https://doaj.org/article/b83bf4c5e2db4e1eaeaab26d621e57b0
Autor:
Arnav Gupta, Sarah K. Sasse, Reena Berman, Margaret A. Gruca, Robin D. Dowell, Hong Wei Chu, Gregory P. Downey, Anthony N. Gerber
Publikováno v:
Physiological genomics. 54(10)
Military Deployment to Southwest Asia and Afghanistan and exposure to toxic airborne particulates has been associated with an increased risk of developing respiratory disease, collectively termed deployment-related respiratory diseases (DRRD). Our kn
Autor:
Raphael Borie, Jonathan Cardwell, Iain R. Konigsberg, Camille M. Moore, Weiming Zhang, Sarah K. Sasse, Fabienne Gally, Evgenia Dobrinskikh, Avram Walts, Julie Powers, Janna Brancato, Mauricio Rojas, Paul J. Wolters, Kevin K. Brown, Timothy S. Blackwell, Tomoko Nakanishi, J. Brent Richards, Anthony N. Gerber, Tasha E. Fingerlin, Norman Sachs, Sara L. Pulit, Zachary Zappala, David A. Schwartz, Ivana V. Yang
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 206:1259-1270
Autor:
Sarah K Sasse, Amber Dahlin, Lynn Sanford, Margaret A. Gruca, Arnav Gupta, Ann Chen Wu, Carlos Iribarren, Robin D. Dowell, Scott T. Weiss, Anthony N. Gerber
Genome wide association studies of asthma have not explained environmental risk or variable clinical efficacy of glucocorticoids. Bidirectional enhancer RNA (eRNA) transcription is a widespread response to environmental signals and glucocorticoids. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::490e96955650a8e5c2fbb3a5a46171ac
https://doi.org/10.1101/2022.11.10.22281906
https://doi.org/10.1101/2022.11.10.22281906
Autor:
Manale El Kharbili, Katja Aviszus, Sarah K. Sasse, Xiaoyun Zhao, Karina A. Serban, Susan M. Majka, Anthony N. Gerber, Fabienne Gally
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 36(5)
Resolution of inflammation is an active process that is tightly regulated to achieve repair and tissue homeostasis. In the absence of resolution, persistent inflammation underlies the pathogenesis of chronic lung disease such as chronic obstructive p
Autor:
Akanksha Bansal, Mahmoud M. Mostafa, Cora Kooi, Sarah K. Sasse, Aubrey N. Michi, Suharsh V. Shah, Richard Leigh, Anthony N. Gerber, Robert Newton
Publikováno v:
The Journal of biological chemistry. 298(4)
While glucocorticoids act via the glucocorticoid receptor (GR; NR3C1) to reduce the expression of many inflammatory genes, repression is not an invariable outcome. Here, we explore synergy occurring between synthetic glucocorticoids (dexamethasone an
Autor:
Margaret Gruca, Anthony N. Gerber, Arnav Gupta, Sarah K. Sasse, Lynn Sanford, Robin D. Dowell
Publikováno v:
The Journal of Biological Chemistry
The heterogeneity of respirable particulates and compounds complicates our understanding of transcriptional responses to air pollution. Here, we address this by applying precision nuclear run-on sequencing and the assay for transposase-accessible chr
Autor:
Robin D. Dowell, Margaret Gruca, Sarah K. Sasse, Anthony N. Gerber, Lynn Sanford, Arnav Gupta
Heterogeneity of respirable particulates and compounds complicates understanding transcriptional responses to air pollution. Here, we address this problem through applying precision nuclear run-on sequencing (PRO-seq) to measure nascent transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cf7f7979d006de6c66f169e9528d894
https://doi.org/10.1101/2021.02.23.432311
https://doi.org/10.1101/2021.02.23.432311
Autor:
Tsukasa Okamoto, Fabienne Gally, Anthony N. Gerber, Bing Ren, Jonathan S. Kurche, Sebastian Preissl, Xiaomeng Hou, Hong W. Chu, Olivier Poirion, David A. Schwartz, Jonathan Cardwell, Sarah K. Sasse, Justin Buchanan, Margaret Gruca, Ivana V. Yang, Robin D. Dowell, Sean P. Colgan
Publikováno v:
JCI Insight, Vol 6, Iss 2 (2021)
JCI Insight
JCI Insight
The G/T transversion rs35705950, located approximately 3 kb upstream of the MUC5B start site, is the cardinal risk factor for idiopathic pulmonary fibrosis (IPF). Here, we investigate the function and chromatin structure of this –3 kb region and pr