Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Sarah K. Highlander"'
Autor:
Sarah K. Highlander, Jason M. Wood, John D. Gillece, Megan Folkerts, Viacheslav Fofanov, Tara Furstenau, Nitin K. Singh, Lisa Guan, Arman Seuylemezian, James N. Benardini, David M. Engelthaler, Kasthuri Venkateswaran, Paul S. Keim
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
The National Aeronautics and Space Administration (NASA) has been monitoring the microbial burden of spacecraft since the 1970’s Viking missions. Originally culture-based and then focused 16S sequencing techniques were used, but we have now applied
Externí odkaz:
https://doaj.org/article/6e144d3cdb0a44009a67bc91f067a5b0
Autor:
Chi Wah Wong, Susan E. Yost, Jin Sun Lee, John D. Gillece, Megan Folkerts, Lauren Reining, Sarah K. Highlander, Zahra Eftekhari, Joanne Mortimer, Yuan Yuan
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Neratinib has great efficacy in treating HER2+ breast cancer but is associated with significant gastrointestinal toxicity. The objective of this pilot study was to understand the association of gut microbiome and neratinib-induced diarrhea. Twenty-fi
Externí odkaz:
https://doaj.org/article/04344c2686dd4b62bc0fdb6eec934bd3
Autor:
Qiyun Zhu, Christopher L. Dupont, Marcus B. Jones, Kevin M. Pham, Zhi-Dong Jiang, Herbert L. DuPont, Sarah K. Highlander
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-20 (2018)
Abstract Background Travelers’ diarrhea (TD) is often caused by enterotoxigenic Escherichia coli, enteroaggregative E. coli, other bacterial pathogens, Norovirus, and occasionally parasites. Nevertheless, standard diagnostic methods fail to identif
Externí odkaz:
https://doaj.org/article/e749764ce0fa484e98f8916916ec9fcf
Autor:
Candace R. Lewis, Kevin S. Bonham, Shelley Hoeft McCann, Alexandra R. Volpe, Viren D’Sa, Marcus Naymik, Matt D. De Both, Matthew J. Huentelman, Kathryn Lemery-Chalfant, Sarah K. Highlander, Sean C. L. Deoni, Vanja Klepac-Ceraj
Publikováno v:
Microorganisms, Vol 9, Iss 8, p 1608 (2021)
Background: While early life exposures such as mode of birth, breastfeeding, and antibiotic use are established regulators of microbiome composition in early childhood, recent research suggests that the social environment may also exert influence. Tw
Externí odkaz:
https://doaj.org/article/15e54b04560544b2ae4194a82fc0b5e7
Autor:
Josh L. Espinoza, Derek M. Harkins, Manolito Torralba, Andres Gomez, Sarah K. Highlander, Marcus B. Jones, Pamela Leong, Richard Saffery, Michelle Bockmann, Claire Kuelbs, Jason M. Inman, Toby Hughes, Jeffrey M. Craig, Karen E. Nelson, Chris L. Dupont
Publikováno v:
mBio, Vol 9, Iss 6 (2018)
ABSTRACT To address the question of how microbial diversity and function in the oral cavities of children relates to caries diagnosis, we surveyed the supragingival plaque biofilm microbiome in 44 juvenile twin pairs. Using shotgun sequencing, we con
Externí odkaz:
https://doaj.org/article/d0f9ec9e3f6946dfaa0c58af1210e690
Autor:
Lauren Reining, Zahra Eftekhari, Megan Folkerts, Sarah K. Highlander, Yuan Yuan, Jin Sun Lee, John D. Gillece, Chi Wah Wong, Joanne E. Mortimer, Susan E. Yost
Publikováno v:
Cancer Research. 81:PS5-41
Background: Neratinib is a potent small molecule tyrosine kinase inhibitor (TKI) of human epidermal growth factor receptors (HER1,2,4). One of the major side effects of neratinib is diarrhea. The human gut contains a dense microbiome ecosystem that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::002fe276131cdd85a191154061e33326
https://doi.org/10.1158/1538-7445.sabcs20-ps5-41
https://doi.org/10.1158/1538-7445.sabcs20-ps5-41
Autor:
Patrick D. Schloss, Matthew L. Jenior, Charles C. Koumpouras, Sarah L. Westcott, Sarah K. Highlander
Publikováno v:
PeerJ, Vol 4, p e1869 (2016)
Over the past 10 years, microbial ecologists have largely abandoned sequencing 16S rRNA genes by the Sanger sequencing method and have instead adopted highly parallelized sequencing platforms. These new platforms, such as 454 and Illumina’s MiSeq,
Externí odkaz:
https://doaj.org/article/43cb332f045c4333963edc4f949dfc0c
Autor:
Jeffrey M. Trent, Sarah K. Highlander, Paulo Gustavo Bergerot, Lauren Reining, Megan Folkerts, JoAnn Hsu, Sumanta K. Pal, John D. Gillece, Nazli Dizman
Publikováno v:
Cancer Medicine
Studies suggest a link between the gut microbiome and metastatic renal cell carcinoma (mRCC) outcomes, including evidence that mRCC patients possess a lower abundance of Bifidobacterium spp. compared to healthy adults. We sought to assess if a Bifido
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab507c2c369d908a9eea2d2203d8223
http://europepmc.org/articles/PMC7826461
http://europepmc.org/articles/PMC7826461
Autor:
Nazli Dizman, Nicholas Salgia, Paulo Gustavo Bergerot, Sumanta K. Pal, Sarah K. Highlander, Jeffrey M. Trent, Manuel Caitano Maia, John D. Gillece, Lauren Reining, Megan Folkerts, JoAnn Hsu
Publikováno v:
European Urology. 78:498-502
Preclinical models and early clinical data suggest an interplay between the gut microbiome and response to immunotherapy in solid tumors including metastatic renal cell carcinoma (mRCC). We sought to characterize the stool microbiome of mRCC patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dc07d2429679e37b95530393a050491
https://doi.org/10.1016/j.eururo.2020.07.011
https://doi.org/10.1016/j.eururo.2020.07.011
Autor:
Nazli Dizman, Luis Meza, Paulo Bergerot, Marice Alcantara, Tanya Dorff, Yung Lyou, Paul Frankel, Yujie Cui, Valerie Mira, Marian Llamas, Joann Hsu, Zeynep Zengin, Nicholas Salgia, Sabrina Salgia, Jasnoor Malhotra, Neal Chawla, Alex Chehrazi-Raffle, Ramya Muddasani, John Gillece, Lauren Reining, Jeff Trent, Motomichi Takahashi, Kentaro Oka, Seiya Higashi, Marcin Kortylewski, Sarah K. Highlander, Sumanta K. Pal
Publikováno v:
Nature medicine. 28(4)
Previous studies have suggested that the gut microbiome influences the response to checkpoint inhibitors (CPIs) in patients with cancer. CBM588 is a bifidogenic live bacterial product that we postulated could augment CPI response through modulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3378fa6e57d09b2c6e662de7b7528b79
https://pubmed.ncbi.nlm.nih.gov/35899808
https://pubmed.ncbi.nlm.nih.gov/35899808