Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sarah K Popp"'
Autor:
Sarita Dhounchak, Sarah K Popp, Debra J Brown, D Ross Laybutt, Trevor J Biden, Stefan R Bornstein, Christopher R Parish, Charmaine J Simeonovic
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252607 (2021)
Heparan sulfate proteoglycans (HSPGs) consist of a core protein with side chains of the glycosaminoglycan heparan sulfate (HS). We have previously identified (i) the HSPGs syndecan-1 (SDC1), and collagen type XVIII (COL18) inside mouse and human isle
Externí odkaz:
https://doaj.org/article/68eb3c59062444408e639f2ff92b388d
Autor:
Charmaine J Simeonovic, Sarah K Popp, Lora M Starrs, Debra J Brown, Andrew F Ziolkowski, Barbara Ludwig, Stefan R Bornstein, J Dennis Wilson, Alberto Pugliese, Thomas W H Kay, Helen E Thomas, Thomas Loudovaris, Fui Jiun Choong, Craig Freeman, Christopher R Parish
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191360 (2018)
Type 1 diabetes (T1D) is an autoimmune disease in which insulin-producing beta cells in pancreatic islets are progressively destroyed. Clinical trials of immunotherapies in recently diagnosed T1D patients have only transiently and partially impacted
Externí odkaz:
https://doaj.org/article/3bfbd0d7d48b4557a8441d019c004f28
Autor:
Alessandra, Petrelli, Sarah K, Popp, Riho, Fukuda, Christopher R, Parish, Emanuele, Bosi, Charmaine J, Simeonovic
Publikováno v:
Frontiers in Immunology. 13
Type 1 diabetes (T1D) is an autoimmune disease resulting from the destruction of insulin-producing beta cells in pancreatic islets. T lymphocytes are the claimed pathogenic effectors but abnormalities of other immune cell types, including neutrophils
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee80096509d55149fb2ea2923be123d
https://doi.org/10.3389/fimmu.2022.930553
https://doi.org/10.3389/fimmu.2022.930553
Autor:
Sarah K. Popp, Federica Vecchio, Debra J. Brown, Riho Fukuda, Yuri Suzuki, Yuma Takeda, Rikako Wakamatsu, Mahalakshmi A. Sarma, Jessica Garrett, Anna Giovenzana, Emanuele Bosi, Antony R.A. Lafferty, Karen J. Brown, Elizabeth E. Gardiner, Lucy A. Coupland, Helen E. Thomas, Beng H. Chong, Christopher R. Parish, Manuela Battaglia, Alessandra Petrelli, Charmaine J. Simeonovic
Publikováno v:
JCI Insight. 7
Platelet-neutrophil aggregates (PNAs) facilitate neutrophil activation and migration and could underpin the recruitment of neutrophils to the pancreas during type 1 diabetes (T1D) pathogenesis. PNAs, measured by flow cytometry, were significantly ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0549b1397607c815ab52c1e3f9579695
https://doi.org/10.1172/jci.insight.153993
https://doi.org/10.1172/jci.insight.153993
Autor:
Sarah K. Popp, Christopher R. Parish, Charmaine J. Simeonovic, Trevor J. Biden, Sarita Dhounchak, D. Ross Laybutt, Debra J. Brown, Stefan R. Bornstein
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 6, p e0252607 (2021)
PLoS ONE, Vol 16, Iss 6, p e0252607 (2021)
Heparan sulfate proteoglycans (HSPGs) consist of a core protein with side chains of the glycosaminoglycan heparan sulfate (HS). We have previously identified (i) the HSPGs syndecan-1 (SDC1), and collagen type XVIII (COL18) inside mouse and human isle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f39bdc0d38a6741497adf8084e0053
https://pubmed.ncbi.nlm.nih.gov/34086738
https://pubmed.ncbi.nlm.nih.gov/34086738
Autor:
Charmaine J, Simeonovic, Sarah K, Popp, Debra J, Brown, Fei-Ju, Li, Antony R A, Lafferty, Craig, Freeman, Christopher R, Parish
Publikováno v:
Advances in experimental medicine and biology. 1221
Type 1 diabetes (T1D) results from autoimmune destruction of insulin-producing beta cells in pancreatic islets. The degradation of the glycosaminoglycan heparan sulfate (HS) by the endo-β-D-glycosidase heparanase plays a critical role in multiple st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b5eadad7925d311d863c6ae86fdcbfa
https://pubmed.ncbi.nlm.nih.gov/32274728
https://pubmed.ncbi.nlm.nih.gov/32274728
Autor:
Fei-Ju Li, Antony R Lafferty, Debra J. Brown, Christopher R. Parish, Sarah K. Popp, Craig Freeman, Charmaine J. Simeonovic
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030345204
Type 1 diabetes (T1D) results from autoimmune destruction of insulin-producing beta cells in pancreatic islets. The degradation of the glycosaminoglycan heparan sulfate (HS) by the endo-β-D-glycosidase heparanase plays a critical role in multiple st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20b27eb3f944ed6eead155feda61973a
https://doi.org/10.1007/978-3-030-34521-1_24
https://doi.org/10.1007/978-3-030-34521-1_24
Autor:
Christopher R. Parish, J. Dennis Wilson, Helen E. Thomas, Fui Jiun Choong, Barbara Ludwig, Andrew F. Ziolkowski, Charmaine J. Simeonovic, Sarah K. Popp, Stefan R. Bornstein, Thomas W.H. Kay, Lora Starrs, Craig Freeman, Thomas Loudovaris, Debra J. Brown, Alberto Pugliese
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191360 (2018)
PLoS ONE
PLoS ONE
Type 1 diabetes (T1D) is an autoimmune disease in which insulin-producing beta cells in pancreatic islets are progressively destroyed. Clinical trials of immunotherapies in recently diagnosed T1D patients have only transiently and partially impacted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b710034fc5ae324ee64bd93770d4b09f
http://europepmc.org/articles/PMC5802856?pdf=render
http://europepmc.org/articles/PMC5802856?pdf=render
Autor:
Andrew F. Ziolkowski, Sarah K. Popp, Craig Freeman, Charmaine J. Simeonovic, Christopher R. Parish
Publikováno v:
Journal of Clinical Investigation. 122:132-141
The autoimmune type 1 diabetes (T1D) that arises spontaneously in NOD mice is considered to be a model of T1D in humans. It is characterized by the invasion of pancreatic islets by mononuclear cells (MNCs), which ultimately leads to destruction of in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d131f15c0fc7d29000247b8e471ede98
https://doi.org/10.1172/jci46177
https://doi.org/10.1172/jci46177
Autor:
Michelle J. Townsend, Barbara van Leeuwen, Damien V. Cordery, J. Dennis Wilson, Michelle F. Paule, Sarah K. Popp, William B. Cowden, Charmaine J. Simeonovic
Publikováno v:
Xenotransplantation. 9:169-182
The rejection of pig proislet xenografts in mice is a CD4 T cell-dependent process in which macrophages play an important role. To assess the potential for activated macrophages to act as effector cells in xenograft destruction, we have examined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c4f197fe92118d515bfb364b1b51a7f
https://doi.org/10.1034/j.1399-3089.2002.01024.x
https://doi.org/10.1034/j.1399-3089.2002.01024.x