Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sarah K Mercier"'
Autor:
Sarah K Mercier, Heather Donaghy, Rachel A Botting, Stuart G Turville, Andrew N Harman, Najla Nasr, Hong Ji, Ulrike Kusebauch, Luis Mendoza, David Shteynberg, Kerrie Sandgren, Richard J Simpson, Robert L Moritz, Anthony L Cunningham
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003700 (2013)
HIV-1 is taken up by immature monocyte derived dendritic cells (iMDDCs) into tetraspanin rich caves from which the virus can either be transferred to T lymphocytes or enter into endosomes resulting in degradation. HIV-1 binding and fusion with the DC
Externí odkaz:
https://doaj.org/article/b648816bfe1347eea9fbd8993249f6ff
Autor:
Anthony L. Cunningham, Sarah K. Mercier, Kerrie J. Sandgren, Sharon R Lewin, Christopher R. Bye, Najla Nasr, Min Kim, Rachel A. Botting, Paul U. Cameron, Andrew N. Harman
Publikováno v:
The Journal of Immunology. 190:66-79
The lineage relationships and fate of human dendritic cells (DCs) have significance for a number of diseases including HIV where both blood and tissue DCs may be infected. We used gene expression profiling of human monocyte and DC subpopulations sort
Autor:
Joey Lai, Stuart Turville, Shamith A. Samarajiwa, Sarah K. Mercier, Michael Gale, Kate L. Jones, Lachlan Robert Gray, Najla Nasr, Melissa J Churchill, Arjun Rustagi, Helen E. Cumming, Johnson Mak, Heather Donaghy, Andrew N. Harman, Valerie Marsden, Anthony L. Cunningham, Paul J. Hertzog
Publikováno v:
Blood. 118:298-308
Many viruses have developed mechanisms to evade the IFN response. Here, HIV-1 was shown to induce a distinct subset of IFN-stimulated genes (ISGs) in monocyte-derived dendritic cells (DCs), without detectable type I or II IFN. These ISGs all containe
Autor:
Norman Olbourne, Sarah K. Mercier, Najla Nasr, Joey Lai, Min Kim, Andrew N. Harman, Paul R Gorry, Rachel A. Botting, Teresa Domagala, Stuart Turville, Anthony L. Cunningham
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 193(5)
Epidermal Langerhans cells (eLCs) uniquely express the C-type lectin receptor langerin in addition to the HIV entry receptors CD4 and CCR5. They are among the first target cells to encounter HIV in the anogenital stratified squamous mucosa during sex
Autor:
Rachel A. Botting, Ulrike Kusebauch, Hong Ji, Najla Nasr, Luis Mendoza, Stuart Turville, Robert L. Moritz, Sarah K. Mercier, Heather Donaghy, Kerrie J. Sandgren, Andrew N. Harman, Anthony L. Cunningham, Richard J. Simpson, David Shteynberg
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003700 (2013)
PLoS Pathogens
PLoS Pathogens
HIV-1 is taken up by immature monocyte derived dendritic cells (iMDDCs) into tetraspanin rich caves from which the virus can either be transferred to T lymphocytes or enter into endosomes resulting in degradation. HIV-1 binding and fusion with the DC
Autor:
Najla Nasr, Sarah K. Mercier, Marianne Kraus, Owen Tang, Christoph Driessen, Andrew N. Harman, Stuart Turville, Christopher R. Bye, Anthony L. Cunningham, Karen Byth, Barry Slobedman, Josh L. Stern
Publikováno v:
Blood
Dendritic cells (DCs) play a key role in the pathogenesis of HIV infection. HIV interacts with these cells through 2 pathways in 2 temporal phases, initially via endocytosis and then via de novo replication. Here the transcriptional response of human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2eb9a8586d057b80cf249478ab96ee2
https://europepmc.org/articles/PMC2710958/
https://europepmc.org/articles/PMC2710958/
Autor:
John Wilkinson, Anthony L. Cunningham, Sarah Watson, Christopher R. Bye, Andrew N. Harman, Sarah K. Mercier
Publikováno v:
Virology Journal
Virology Journal, Vol 4, Iss 1, p 130 (2007)
Virology Journal, Vol 4, Iss 1, p 130 (2007)
The choice of an appropriate housekeeping gene for normalisation purposes has now become an essential requirement when designing QPCR experiments. This is of particular importance when using QPCR to measure viral and cellular gene transcription level
Autor:
Sarah K. Mercier, Heather Donaghy, Rachel A. Botting, Stuart G. Turville, Andrew N. Harman, Najla Nasr, Hong Ji, Ulrike Kusebauch, Luis Mendoza, David Shteynberg, Kerrie Sandgren, Richard J. Simpson, Robert L. Moritz, Anthony L. Cunningham
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/180ed81c7c9b4da485a8b723fefe9145