Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Sarah K England"'
Autor:
Neal G. Ravindra, Camilo Espinosa, Eloïse Berson, Thanaphong Phongpreecha, Peinan Zhao, Martin Becker, Alan L. Chang, Sayane Shome, Ivana Marić, Davide De Francesco, Samson Mataraso, Geetha Saarunya, Melan Thuraiappah, Lei Xue, Brice Gaudillière, Martin S. Angst, Gary M. Shaw, Erik D. Herzog, David K. Stevenson, Sarah K. England, Nima Aghaeepour
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Preterm birth (PTB) is the leading cause of infant mortality globally. Research has focused on developing predictive models for PTB without prioritizing cost-effective interventions. Physical activity and sleep present unique opportunities f
Externí odkaz:
https://doaj.org/article/05646d15d14e4a168c26939cdb678d79
Autor:
Barbara B. Warner, Bruce A. Rosa, I. Malick Ndao, Phillip I. Tarr, J. Philip Miller, Sarah K. England, Joan L. Luby, Cynthia E. Rogers, Carla Hall-Moore, Renay E. Bryant, Jacqueline D. Wang, Laura A. Linneman, Tara A. Smyser, Christopher D. Smyser, Deanna M. Barch, Gregory E. Miller, Edith Chen, John Martin, Makedonka Mitreva
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Health disparities are driven by underlying social disadvantage and psychosocial stressors. However, how social disadvantage and psychosocial stressors lead to adverse health outcomes is unclear, particularly when exposure begins prenatally.
Externí odkaz:
https://doaj.org/article/e02c20e1c051453987d0471351f063de
Autor:
Yingye Fang, Erin L. Reinl, Audrey Liu, Trinidi D. Prochaska, Manasi Malik, Antonina I. Frolova, Sarah K. England, Princess I. Imoukhuede
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e25761- (2024)
Oxytocin acts through the oxytocin receptor (OXTR) to modulate uterine contractility. We previously identified OXTR genetic variants and showed that, in HEK293T cells, two of the OXTR protein variants localized to the cell surface less than wild-type
Externí odkaz:
https://doaj.org/article/de72c2ef8acb44f8828eaa62a83993ef
Autor:
Tusar Giri, Jia Jiang, Zhiqiang Xu, Ronald McCarthy, Carmen M. Halabi, Eric Tycksen, Alison G. Cahill, Sarah K. England, Arvind Palanisamy
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Despite the widespread use of oxytocin for induction of labor, mechanistic insights into fetal/neonatal wellbeing are lacking because of the absence of an animal model that recapitulates modern obstetric practice. Here, we create and validat
Externí odkaz:
https://doaj.org/article/4d38c134bb1f485a9120cb40bbe9b4c8
Autor:
Zili Xie, Jing Feng, Tao Cai, Ronald McCarthy, Mark D. Eschbach II, Yuhui Wang, Yonghui Zhao, Zhihua Yi, Kaikai Zang, Yi Yuan, Xueming Hu, Fengxian Li, Qin Liu, Aditi Das, Sarah K. England, Hongzhen Hu
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
Pain emanating from the female reproductive tract is notoriously difficult to treat, and the prevalence of transient pelvic pain has been placed as high as 70%–80% in women surveyed. Although sex hormones, especially estrogen, are thought to underl
Externí odkaz:
https://doaj.org/article/1e3179dd5f3f45ad820c9ae4eb63a426
Autor:
Molly J Stout, Jessica Chubiz, Nandini Raghuraman, Peinan Zhao, Methodius G Tuuli, Lihong V Wang, Alison G Cahill, Phillip S Cuculich, Yong Wang, Emily S Jungheim, Erik D Herzog, Justin Fay, Alan L Schwartz, George A Macones, Sarah K England
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0272155 (2022)
BackgroundWorldwide, 10% of babies are born preterm, defined as a live birth before 37 weeks of gestation. Preterm birth is the leading cause of neonatal death, and survivors face lifelong risks of adverse outcomes. New approaches with large sample s
Externí odkaz:
https://doaj.org/article/516ff6d9829c462e852399634a2070f6
Autor:
Juan J. Ferreira, Chinwendu Amazu, Lis C. Puga-Molina, Xiaofeng Ma, Sarah K. England, Celia M. Santi
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103210- (2021)
Summary: Depolarization of the myometrial smooth muscle cell (MSMC) resting membrane potential is necessary for the uterus to transition from a quiescent state to a contractile state. The molecular mechanisms involved in this transition are not compl
Externí odkaz:
https://doaj.org/article/7110ec77e6cd4632b93850830151803b
Autor:
Joan L. Luby, Sarah K. England, Deanna M. Barch, Barbara B. Warner, Cynthia Rogers, Christopher D. Smyser, Regina Triplett, Jyoti Arora, Tara A. Smyser, George M. Slavich, Peinan Zhao, Molly Stout, Erik Herzog, J. Philip Miller
Publikováno v:
Journal of Perinatology. 43:477-483
Objective Whether psychosocial adversity during pregnancy impacts fetal health outcomes at birth remains underexplored. This is a critical issue given significant social disadvantage and psychosocial stress faced by pregnant women worldwide. Study de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0415abda321570a8b7a7296c0d26fb98
https://doi.org/10.1038/s41372-023-01643-2
https://doi.org/10.1038/s41372-023-01643-2
Autor:
Nathaniel W. York, Helen Parker, Zili Xie, David Tyus, Maham Akbar Waheed, Zihan Yan, Dorothy K. Grange, Maria Sara Remedi, Sarah K. England, Hongzhen Hu, Colin G. Nichols
Publikováno v:
JCI Insight, Vol 5, Iss 23 (2020)
Cantú syndrome (CS), caused by gain-of-function (GOF) mutations in pore-forming (Kir6.1, KCNJ8) and accessory (SUR2, ABCC9) ATP-sensitive potassium (KATP) channel subunit genes, is frequently accompanied by gastrointestinal (GI) dysmotility, and we
Externí odkaz:
https://doaj.org/article/573f155ab6f149b99f5480cd8417f575
Autor:
Tusar Giri, Jia Jiang, Zhiqiang Xu, Ronald McCarthy, Carmen M. Halabi, Eric Tycksen, Alison G. Cahill, Sarah K. England, Arvind Palanisamy
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/30a1f38063dd469f812b17e865c82659