Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sarah J. West"'
Publikováno v:
Frontiers in Pain Research, Vol 5 (2024)
ObjectiveQuantitative sensory testing is often used to investigate pain in the context of experimental and clinical research studies. However, many of the devices used for QST protocols are only available in resource rich environments, thereby inadve
Externí odkaz:
https://doaj.org/article/6d17eba60e7c40b1abb4143aaa313370
Autor:
Christopher M. Tegley, Mehrnouch Motamedi, Dale E. Mais, Keith B. Marschke, Josef D. Ringgenberg, Sarah J. West, Lin Zhi, William T. Schrader, Barbara Pio, Todd K. Jones, James P. Edwards
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:2075-2078
A series of 1,2-dihydrochromeno[3,4-f]quinoline derivatives was synthesized and tested in biological assays to evaluate the nonsteroidal progesterone receptor modulator pharmacophore (4) as antiprogestins. A number of potent analogues were identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28915ebc3cfc48f929f24dd1d13142fe
https://doi.org/10.1016/s0960-894x(03)00256-7
https://doi.org/10.1016/s0960-894x(03)00256-7
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. :145-153
Measurements have been made of the light scattering properties of emulsion droplets produced using a Microfluidizer. The droplet size distributions were measured by both Integrated Light Scattering (ILS) over a wide range of scattering angles, and by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30271855de3f660d116a5b539416511c
https://doi.org/10.1016/s0927-7757(97)03783-7
https://doi.org/10.1016/s0927-7757(97)03783-7
Autor:
Keith B. Marschke, Andres Negro-Vilar, Mehrnoush Motamedi, Esther A. Martinborough, William Y. Chang, Sarah J. West, E. Adam Kallel, Arjan van Oeveren, Lin Zhi, Shuo Zhao, Yixing Shen, Francisco J. López
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(6)
A series of selective androgen receptor modulators (SARMs) with a wide spectrum of receptor modulating activities was developed based on optimization of the 4-substituted 6-bisalkylamino-2-quinolinones (3). Significance of the trifluoromethyl group o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1906b957fc7d008590c87b18d7b55a99
https://pubmed.ncbi.nlm.nih.gov/17267219
https://pubmed.ncbi.nlm.nih.gov/17267219
Autor:
Sarah J. West, George A. Doherty, Gary Chrebet, Richard Hajdu, James A. Milligan, Naomi Nomura, Carol Ann Keohane, Hugh Rosen, Huijuan Xie, Suzanne M. Mandala, Mark Rosenbach, Shu-Yu Sun, Michael J. Forrest, Gan-Ju Shei, Jeffrey J. Hale, James D. Bergstrom, Sander G. Mills, Deborah Card, Leslie Toth
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(13)
Structurally modified 3-(N-benzylamino)propylphosphonic acid S1P receptor agonists that maintain affinity for S1P1, and have decreased affinity for S1P3 are efficacious, but exhibit decreased acute cardiovascular toxicity in rodents than do nonselect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865fad3df6cfb865d4a5870ef4c4f90f
https://pubmed.ncbi.nlm.nih.gov/15177461
https://pubmed.ncbi.nlm.nih.gov/15177461
Autor:
Lin Zhi, Todd K. Jones, James P. Edwards, Christopher M. Tegley, Mark E. Goldman, Luc J. Farmer, David T. Winn, Sarah J. West, Pooley Charlotte L F, Dale E. Mais, Keith B. Marschke, Lawrence G. Hamann
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(19)
A series of nonsteroidal human progesterone receptor (hPR) antagonists based on conformationally-restricted analogues of a 6-aryl-1,2-dihydro-2,2,4-trimethylquinoline pharmacophore were synthesized and evaluated for their ability to bind to the human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50bc5711ef4413690fecc5cb0cd0133c
https://pubmed.ncbi.nlm.nih.gov/9873612
https://pubmed.ncbi.nlm.nih.gov/9873612
Publikováno v:
HETEROCYCLES. 34:483
Pictet-Spengler condensation of N b -benzyl-β-methyltryptophan methyl ester (2RS, 3SR; 4) with aldehydes followed by benzylation afforded trans, cis-1,3,4-trisubstituted 1,2,3,4-tetrahydro-β-carbolines in complete stereospecific fashion. Tetrahydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87d92d7cb3f7429614517cf096bd1f2e
https://doi.org/10.3987/com-91-5912
https://doi.org/10.3987/com-91-5912