Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sarah J. O'Meara"'
Autor:
Maja Di Rocco, Eduardo Forleo-Neto, Robert Pignolo, Richard Keen, Philippe Orcel, Thomas Funck-Brentano, Christian Roux, Sami Kolta, Annalisa Madeo, Judith S Bubbear, Jacek Tabarkiewicz, Małgorzata Szczepanek, Javier Bachiller-Corral, Angela M Cheung, Kathryn M Dahir, Esmée Botman, Pieter G Raijmakers, Mona Al Mukaddam, Lianne Tile, Cynthia Portal-Celhay, Neena Sarkar, Peijie Hou, Bret Musser, Anita Boyapati, Kusha Mohammadi, Scott Mellis, Andrew J. Rankin, Aris N. Economides, Dinko Gonzalez Trotter, Gary Herman, Sarah J. O’Meara, Richard DelGizzi, David M. Weinreich, George D. Yancopolous, E. Marelise W. Eekhoff, Frederick S. Kaplan
BackgroundFibrodysplasia ossificans progressiva (FOP), an ultra-rare disorder caused by mutations in the gene encoding activin A receptor type 1 (ACVR1), is characterized by painful flare-ups and cumulative heterotopic ossification (HO). Garetosmab,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c882b21013c888887c75dbb8599f68a0
https://doi.org/10.1101/2023.01.11.23284254
https://doi.org/10.1101/2023.01.11.23284254
Autor:
B. Therese Kinsella, Derick Mitchell, Catherine Godson, John Crean, Andrew Gaffney, Sarah J. O'Meara
Publikováno v:
Journal of Biological Chemistry. 282:15606-15618
Mesangial cell proliferation is pivotal to the pathology of glomerular injury in inflammation. We have previously reported that lipoxins, endogenously produced eicosanoids with anti-inflammatory and pro-resolution bioactions, can inhibit mesangial ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f03ec356a2596c3ad43f22835f1b3e9
https://doi.org/10.1074/jbc.m611004200
https://doi.org/10.1074/jbc.m611004200
Autor:
B. Therese Kinsella, Sarah J. O'Meara
Publikováno v:
British Journal of Pharmacology. 143:318-330
The human (h) and mouse (m) prostacyclin receptors (IPs) undergo isoprenylation through attachment of a C-15 farnesyl moiety within their conserved carboxyl terminal -CSLC sequences. Herein, the effects of a novel farnesyl transferase inhibitor R1157
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fbf04207aef81098568a2d69c6799ad
https://doi.org/10.1038/sj.bjp.0705956
https://doi.org/10.1038/sj.bjp.0705956
Autor:
B. Therese Kinsella, Sarah J. O'Meara
Publikováno v:
British Journal of Pharmacology. 143:292-302
Prostacyclin plays a central role within the vasculature. We have previously established that the prostacyclin receptor (IP) undergoes isoprenylation, a lipid modification obligate for its function. The aim of the current study was to investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::989f6446a61233fa92df7fe44fda31ad
https://doi.org/10.1038/sj.bjp.0705947
https://doi.org/10.1038/sj.bjp.0705947
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 182(6)
Lipoxins (LX) are a class of eicosanoid that possesses a wide spectrum of antiinflammatory and proresolution bioactions. Here we have investigated the impact of the endogenously produced eicosanoid LXA4 on endothelial cell inflammatory, proliferative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ecace9da3263c445062ff198cc46a5
https://pubmed.ncbi.nlm.nih.gov/19265161
https://pubmed.ncbi.nlm.nih.gov/19265161
Publikováno v:
Investigative ophthalmologyvisual science. 48(9)
PURPOSE. Proliferative vitreoretinopathy (PVR), a major reason for failure of retinal detachment surgery, is characterized by the formation of scarlike tissue that contains transdifferentiated retinal pigment epithelial (RPE) cells. The scar tissue o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120b0c35eb99c079dbe9ae4bd36901f4
https://pubmed.ncbi.nlm.nih.gov/17724219
https://pubmed.ncbi.nlm.nih.gov/17724219
Autor:
Derick, Mitchell, Sarah J, O'Meara, Andrew, Gaffney, John K G, Crean, B Therese, Kinsella, Catherine, Godson
Publikováno v:
The Journal of biological chemistry. 282(21)
Mesangial cell proliferation is pivotal to the pathology of glomerular injury in inflammation. We have previously reported that lipoxins, endogenously produced eicosanoids with anti-inflammatory and pro-resolution bioactions, can inhibit mesangial ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d601d1713d722d7fcd0452ca2875c2c
https://pubmed.ncbi.nlm.nih.gov/17403678
https://pubmed.ncbi.nlm.nih.gov/17403678
Publikováno v:
Reviews of Physiology Biochemistry and Pharmacology ISBN: 9783540776031
Lipoxins (LXs) are endogenously produced eicosanoids that are typically generated by transcellular biosynthesis. These trihydroxytetraene-containing lipid mediators and their stable synthetic analogues possess a wide spectrum of anti-inflammatory and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db7143ee28e38e0183b0a2d80a1b0315
https://doi.org/10.1007/112_2006_0606
https://doi.org/10.1007/112_2006_0606
Autor:
Sarah J, O'Meara, B Therese, Kinsella
Publikováno v:
British journal of pharmacology. 143(2)
The human (h) and mouse (m) prostacyclin receptors (IPs) undergo isoprenylation through attachment of a C-15 farnesyl moiety within their conserved carboxyl terminal -CSLC sequences. Herein, the effects of a novel farnesyl transferase inhibitor R1157
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81f7c2eb07d9253234e635ed96a4df68
https://pubmed.ncbi.nlm.nih.gov/28233296
https://pubmed.ncbi.nlm.nih.gov/28233296