Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sarah J. Northall"'
Autor:
Alessandro Stirpe, Nora Guidotti, Sarah J Northall, Sinan Kilic, Alexandre Hainard, Oscar Vadas, Beat Fierz, Thomas Schalch
Publikováno v:
eLife, Vol 10 (2021)
The SUV39 class of methyltransferase enzymes deposits histone H3 lysine 9 di- and trimethylation (H3K9me2/3), the hallmark of constitutive heterochromatin. How these enzymes are regulated to mark specific genomic regions as heterochromatic is poorly
Externí odkaz:
https://doaj.org/article/9fce28dce8f64cc388467c3c13dde5f4
Autor:
Oliver J Wilkinson, Alejandro Martín-González, Haejoo Kang, Sarah J Northall, Dale B Wigley, Fernando Moreno-Herrero, Mark Simon Dillingham
Publikováno v:
eLife, Vol 8 (2019)
CtIP is involved in the resection of broken DNA during the S and G2 phases of the cell cycle for repair by recombination. Acting with the MRN complex, it plays a particularly important role in handling complex DNA end structures by localised nucleoly
Externí odkaz:
https://doaj.org/article/990f52da8a4c4714a3896f10d6bc2499
Publikováno v:
Current Opinion in Structural Biology
Eukaryotic genomes are segregated into active euchromatic and repressed heterochromatic compartments. Gene regulatory networks, chromosomal structures, and genome integrity rely on the timely and locus-specific establishment of active and silent stat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1c0adcd9262f74d224ebc0f7a455ec
https://pubmed.ncbi.nlm.nih.gov/34303934
https://pubmed.ncbi.nlm.nih.gov/34303934
Autor:
Tabitha Jenkins, Sarah J. Northall, Rebecca Lever, Panos Soultanas, Christopher D.O. Cooper, Andrew Cubbon, Denis Ptchelkine, Hannah Betts, Vincenzo Taresco, Peter J. McHugh, Edward L. Bolt
Publikováno v:
NAR Cancer
Genome instability is a characteristic enabling factor for carcinogenesis. HelQ helicase is a component of human DNA maintenance systems that prevent or reverse genome instability arising during DNA replication. Here, we provide details of the molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a302c643896100694713f42ec0efef4
https://doi.org/10.1093/narcan/zcaa043
https://doi.org/10.1093/narcan/zcaa043
Autor:
Nora Guidotti, Sarah J. Northall, Alessandro Stirpe, Alexandre Hainard, Sinan Kilic, Oscar Vadas, Thomas Schalch, Beat Fierz
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
The SUV39 class of methyltransferase enzymes deposits histone H3 lysine 9 di- and trimethylation (H3K9me2/3), the hallmark of constitutive heterochromatin. How these enzymes are regulated to mark specific genomic regions as heterochromatic is poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c9be829d56fa33d095f690d2fd376d
https://pubmed.ncbi.nlm.nih.gov/34524082
https://pubmed.ncbi.nlm.nih.gov/34524082
Autor:
Oscar Vadas, Sinan Kilic, Sarah J. Northall, Nora Guidotti, Beat Fierz, Alessandro Stirpe, Thomas Schalch, Alexandre Hainard
The SUV39 class of methyltransferase enzymes deposits histone lysine 9 di- and tri-methylation (H3K9me2/3), the epigenetic hallmark of constitutive heterochromatin, which serves as the central recruitment platform for the heterochromatic silencing ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46d068a03b6766426f255f4219b8e909
https://doi.org/10.1101/2020.06.30.177071
https://doi.org/10.1101/2020.06.30.177071
Autor:
Edward L. Bolt, Panos Soultanas, Denis Ptchelkine, Tabitha Jenkins, Christopher D.O. Cooper, Sarah J. Northall, Vincenzo Taresco
Cells reactivate compromised DNA replication forks using enzymes that include DNA helicases for separating DNA strands and remodelling protein-DNA complexes. HelQ helicase promotes replication-coupled DNA repair in mammals in a network of interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d582533ef7617bafa0b7ac76bcdf9ae7
https://doi.org/10.1101/511758
https://doi.org/10.1101/511758
Autor:
Alejandro Martín-González, Oliver J Wilkinson, Mark S. Dillingham, Haejoo Kang, Dale B. Wigley, Fernando Moreno-Herrero, Sarah J Northall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8a3dafa476503c7cd4a09bcf320161a
https://doi.org/10.7554/elife.42129.027
https://doi.org/10.7554/elife.42129.027
Autor:
Mark S. Dillingham, Alejandro Martín-González, Moreno-Hererro F, Dale B. Wigley, Haejoo Kang, Sarah J Northall, Oliver J Wilkinson
SummaryCtIP is involved in the resection of double-stranded DNA breaks during the S and G2 phases of the cell cycle for repair by homologous recombination. Acting in concert with the MRN complex, it plays a particularly important role in handling com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2306c536a186030a2ebec65edd884e