Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sarah J. Meyer"'
Autor:
Michael Schmidt, Alexandra T. Linder, Marina Korn, Nick Schellenberg, Sarah J. Meyer, Falk Nimmerjahn, Anja Werner, Markus Abeln, Rita Gerardy-Schahn, Anja K. Münster-Kühnel, Lars Nitschke
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Sialic acids are found as terminal sugars on glycan structures on cellular surfaces. T cells carry these sialoglycans abundantly, and they are thought to serve multiple functions in cell adhesion, cell migration, and protection from complement attack
Externí odkaz:
https://doaj.org/article/8c5b3ce0d2684371a533192aaf40fe7f
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
CD22 and Siglec-G are members of the Siglec family. Both are inhibitory co-receptors on the surface of B cells and inhibit B-cell receptor induced signaling, characterized by inhibition of the calcium mobilization and cellular activation. CD22 functi
Externí odkaz:
https://doaj.org/article/b48c6c77f4934a069d1f982370f20fec
Autor:
Sarah J Meyer, Thomas Winkler, Charlotte Wadewitz, Lars Nitschke, Marie Steffensen, Thomas Weisenburger, Andreas Acs
Publikováno v:
The Journal of Immunology. 207:1018-1032
Germinal center reactions are established during a thymus-dependent immune response. Germinal center (GC) B cells are rapidly proliferating and undergo somatic hypermutation in Ab genes. This results in the production of high-affinity Abs and establi
Autor:
Lars Nitschke, Lena Reimann, Alexander Böser, Sarah J Meyer, Barbara Bertocci, Bettina Warscheid, Claudia Koller, Marina A Korn
Publikováno v:
The Journal of Immunology. 204:3360-3374
B lymphocytes are important players of the adaptive immune system. However, not just activation of B cells but also regulation of B cell signaling is important to prevent hyperactivity and dysregulation of the immune response. Different mechanisms an
Autor:
Jhon R. Enterina, Susmita Sarkar, Laura Streith, Jaesoo Jung, Britni M. Arlian, Sarah J. Meyer, Hiromu Takematsu, Changchun Xiao, Troy A. Baldwin, Lars Nitschke, Mark J. Shlomchik, James C. Paulson, Matthew S. Macauley
Publikováno v:
Cell reports. 38(11)
Germinal centers (GCs) are essential for antibody affinity maturation. GC B cells have a unique repertoire of cell surface glycans compared with naive B cells, yet functional roles for changes in glycosylation in the GC have yet to be ascribed. Detec
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 201(7)
Siglec-G and CD22 are inhibitory receptors on B cells and play an important role in the maintenance of tolerance. Although both molecules are expressed on all B cell populations at a similar level, Siglec-G was found to regulate exclusively B1a cells