Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Sarah J. Chittenden"'
Autor:
Glenn D. Flux, Ana Ribeiro, Yong Du, Paul Md Gape, Sarah J. Chittenden, Jim Thurston, Jonathan Gear, Rebecca Gregory, Martin Lee, Iain Murray, Carla Abreu, Dominic P Rushforth
Publikováno v:
The British Journal of Radiology
There is continuing debate concerning the risks of secondary malignancies from low levels of radiation exposure. The current model used for radiation protection is predicated on the assumption that even very low levels of exposure may entail risk. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412e54b8801d1d7242be483cdcabcd09
https://pubmed.ncbi.nlm.nih.gov/32903035
https://pubmed.ncbi.nlm.nih.gov/32903035
Autor:
Jan, Taprogge, Iain, Murray, Jonathan, Gear, Sarah J, Chittenden, Christopher C, Parker, Glenn D, Flux
Publikováno v:
International journal of radiation oncology, biology, physics. 105(4)
A compartmental model was developed based on activity retention data from 6 patients (2 treatments of 110 kBq/kgA single bone compartment cannot accurately describe activity retention in the skeleton. The addition of a second bone compartment improve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e023e325c7e7f76040b8f4fb83ca90f
https://pubmed.ncbi.nlm.nih.gov/31349058
https://pubmed.ncbi.nlm.nih.gov/31349058
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics
Purpose 223Ra-Dichloride is used for treatment of patients with metastatic bone disease from castration-resistant prostate cancer. The uptake and mechanism of action of 223Ra-Dichloride is not well understood. The aim of this work was to develop a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6121ccd1af8e27b6978886ba71d5ae
Autor:
Rebecca Gregory, J L Wevrett, Steve Jeans, Jonathan Gear, Jonathan Wadsley, Sarah Brown, Martha Stuffins, Jill Tipping, Sarah J. Chittenden, Heather Polydor, Gerry Gillen, Nathan Dickson, Glenn D. Flux, Brian Murby, Iain Murray, Darren G. Morgan, Francesca Leek, Aida Hallam, David O. Hall, Colin Brown, Matthew Guy, Sofia Michopoulou, James Scuffham, Andrew Fenwick
Publikováno v:
Physics in Medicine & Biology
The SEL-I-METRY trial (EudraCT No 2015-002269-47) is the first multicentre trial to investigate the role of 123I and 131I SPECT/CT-based tumour dosimetry to predict response to radioiodine therapy. Standardised dosimetry methodology is essential to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0314353186ffe7a8824510b3256639
Autor:
Joe M. O'Sullivan, Bernadette Johnson, V. Ralph McCready, Glenn D. Flux, Ana M. Denis-Bacelar, Antigoni Divoli, David P. Dearnaley, Yong Du, Sarah J. Chittenden
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Denis-Bacelar, A M, Chittenden, S J, Dearnaley, D P, Divoli, A, O'Sullivan, J M, McCready, V R, Johnson, B, Du, Y & Flux, G D 2017, ' Phase I/II trials of (186)Re-HEDP in metastatic castration-resistant prostate cancer: post-hoc analysis of the impact of administered activity and dosimetry on survival ', European Journal of Nuclear Medicine and Molecular Imaging, vol. 44, no. 4, pp. 620-629 . https://doi.org/10.1007/s00259-016-3543-x
Denis-Bacelar, A M, Chittenden, S J, Dearnaley, D P, Divoli, A, O'Sullivan, J M, McCready, V R, Johnson, B, Du, Y & Flux, G D 2017, ' Phase I/II trials of (186)Re-HEDP in metastatic castration-resistant prostate cancer: post-hoc analysis of the impact of administered activity and dosimetry on survival ', European Journal of Nuclear Medicine and Molecular Imaging, vol. 44, no. 4, pp. 620-629 . https://doi.org/10.1007/s00259-016-3543-x
PURPOSE: To investigate the role of patient-specific dosimetry as a predictive marker of survival and as a potential tool for individualised molecular radiotherapy treatment planning of bone metastases from castration-resistant prostate cancer, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c46a6152b373e95545688fcbadc4535
http://europepmc.org/articles/PMC5323472
http://europepmc.org/articles/PMC5323472
Autor:
Sarah J. Chittenden, Glenn D. Flux, Bernadette Johnson, Joe M. O'Sullivan, V. Ralph McCready, David P. Dearnaley, Ana M. Denis-Bacelar, Antigoni Divoli
Publikováno v:
The British Journal of Radiology
Denis-Bacelar, A M, Chittenden, S J, McCready, V R, Divoli, A, Dearnaley, D P, O'Sullivan, J M, Johnson, B & Flux, G D 2018, ' Bone lesion absorbed dose profiles in patients with metastatic prostate cancer treated with molecular radiotherapy ', British Journal of Radiology, vol. 91, 20170795 . https://doi.org/10.1259/bjr.20170795
Denis-Bacelar, A M, Chittenden, S J, McCready, V R, Divoli, A, Dearnaley, D P, O'Sullivan, J M, Johnson, B & Flux, G D 2018, ' Bone lesion absorbed dose profiles in patients with metastatic prostate cancer treated with molecular radiotherapy ', British Journal of Radiology, vol. 91, 20170795 . https://doi.org/10.1259/bjr.20170795
OBJECTIVE:The aim of this study was to calculate the range of absorbed doses that could potentially be delivered by a variety of radiopharmaceuticals and typical fixed administered activities used for bone pain palliation in a cohort of patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d03e73631bf1c28f10da66157ef3ac1
https://pubmed.ncbi.nlm.nih.gov/29293372
https://pubmed.ncbi.nlm.nih.gov/29293372
Autor:
Yong Du, Sarah J. Chittenden, Ana M. Denis-Bacelar, Antigoni Divoli, Glenn D. Flux, David P. Dearnaley, Bernadette Johnson, V. Ralph McCready, Joe M. O'Sullivan
Publikováno v:
European journal of nuclear medicine and molecular imaging. 45(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce93b1bc04bd934205d2c202bda78a30
https://pubmed.ncbi.nlm.nih.gov/28861597
https://pubmed.ncbi.nlm.nih.gov/28861597
Publikováno v:
Nuclear medicine communications. 39(2)
ObjectiveThe aim of the study was to determine the fraction of administered activity that was excreted and retained by a small cohort of patients who each received treatment with radium-223 dichloride (Ra-223). Ra-223 is an -emitting radionuclide tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f477adbcaa732ad92f97b35ec1bfc173
https://pubmed.ncbi.nlm.nih.gov/29189490
https://pubmed.ncbi.nlm.nih.gov/29189490
Autor:
Ana M, Denis-Bacelar, Sarah J, Chittenden, Iain, Murray, Antigoni, Divoli, V, Ralph McCready, David P, Dearnaley, Joe M, O'Sullivan, Bernadette, Johnson, Glenn D, Flux
Publikováno v:
Physics in Medicine and Biology
Skeletal tumour burden is a biomarker of prognosis and survival in cancer patients. This study proposes a novel method based on the linear quadratic model to predict the reduction in metastatic tumour burden as a function of the absorbed doses delive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6bd36300fc96bf7b0c611ac91be823bc
https://pubmed.ncbi.nlm.nih.gov/28291739
https://pubmed.ncbi.nlm.nih.gov/28291739
Autor:
Iain, Murray, Sarah J, Chittenden, Ana M, Denis-Bacelar, Cecilia, Hindorf, Christopher C, Parker, Sue, Chua, Glenn D, Flux
Publikováno v:
European journal of nuclear medicine and molecular imaging. 44(11)
The aims of this study were to calculate bone lesion absorbed doses resulting from a weight-based administration ofFive patients received two intravenous injections ofAbsorbed doses to metastatic bone lesions ranged from 0.6 Gy to 44.1 Gy. For indivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9f4c2658164a1e73bd6a9579cd7b165
https://pubmed.ncbi.nlm.nih.gov/29103200
https://pubmed.ncbi.nlm.nih.gov/29103200