Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Sarah J. B. Snelling"'
Autor:
Jolet Y. Mimpen, Robert Hedley, Anna Ridley, Mathew J. Baldwin, Dylan Windell, Ananya Bhalla, Lorenzo Ramos-Mucci, Christopher D. Buckley, Mark C. Coles, Abtin Alvand, Andrew J. Price, Andrew J. Carr, Stephanie G. Dakin, Sarah J. B. Snelling
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-15 (2023)
Abstract Objectives Osteoarthritis (OA) is increasingly recognised as a whole joint disease, with an important role for synovium. However, the repertoire of immune cells and fibroblasts that constitute OA synovium remains understudied. This study aim
Externí odkaz:
https://doaj.org/article/ad4812c86da64d16ae2f61590a6143f6
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Interleukin (IL)-17A, a pro-inflammatory cytokine that is linked to the pathology of several inflammatory diseases, has been shown to be upregulated in early human tendinopathy and to mediate inflammatory and tissue remodelling events. However, it re
Externí odkaz:
https://doaj.org/article/5cfee772202441d8bc7b815beaf17b6f
Publikováno v:
Rheumatology. 62
Background/Aims Traditionally viewed from the perspective of cartilage degeneration, osteoarthritis is increasingly seen as a disease of global joint dysfunction. Connective tissue extracellular matrix (ECM) is a crucial determinant of joint mechanob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58186ac478d8fca4e63298fa6e9061b0
https://doi.org/10.1093/rheumatology/kead104.117
https://doi.org/10.1093/rheumatology/kead104.117
Autor:
L H Appleton, Sarah J. B. Snelling, R J Murphy, Bridget Watkins, Wataru Morita, Kim Wheway, Stephanie G. Dakin, Andrew Carr
Publikováno v:
The American Journal of Sports Medicine. 49:1892-1903
Background: Tendons heal by fibrotic repair, increasing the likelihood of reinjury. Animal tendon injury and overuse models have identified transforming growth factor beta (TGF-β) and bone morphogenetic proteins (BMPs) as growth factors actively inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396fd057f7720a09803bfe138f77dc51
https://doi.org/10.1177/03635465211011158
https://doi.org/10.1177/03635465211011158
Autor:
Andrey Nezhentsev, Roxanna E Abhari, Mathew J Baldwin, Jolet Y Mimpen, Edyta Augustyniak, Mark Isaacs, Pierre-Alexis Mouthuy, Andrew J Carr, Sarah J. B Snelling
Publikováno v:
Rheumatology. 61
Background/Aims Recurrent tears after surgical tendon repair remain common, with 40% of rotator cuff repairs failing within one year. Repair failures can be partly attributed to the use of sutures not designed for the tendon cellular niche nor design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76c2022071c473ffc44b1162cfb77d5b
https://doi.org/10.1093/rheumatology/keac133.280
https://doi.org/10.1093/rheumatology/keac133.280
Autor:
Philippa A. Hulley, Peter C. Taylor, Catherine Swales, Sarah J. B. Snelling, Gary S. Collins, Chethan Jayadev, Andrew Price
Publikováno v:
Bone & Joint Research, Vol 9, Iss 9, Pp 623-632 (2020)
Aims The lack of disease-modifying treatments for osteoarthritis (OA) is linked to a shortage of suitable biomarkers. This study combines multi-molecule synovial fluid analysis with machine learning to produce an accurate diagnostic biomarker model f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae3f60fc58a4f5b046b02cf1e3b6178
https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.99.BJR-2019-0192.R1
https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.99.BJR-2019-0192.R1
Autor:
Mustafa S. Rashid, Sarah J. B. Snelling, Stephanie G. Dakin, Kim Wheway, Bridget Watkins, Navraj S Nagra, Richard J. Smith, Andrew Carr
Publikováno v:
Acta Orthopaedica
article-version (VoR) Version of Record
Acta Orthopaedica, Vol 91, Iss 6, Pp 782-788 (2020)
article-version (VoR) Version of Record
Acta Orthopaedica, Vol 91, Iss 6, Pp 782-788 (2020)
Background and purpose - Biological patches can be used to augment rotator cuff tendon repair in an attempt to improve healing and reduce rates of re-rupture. However, little is known about the in vivo tissue response to these patches. We assessed na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a25b0152e6d7083a45e4872e6d589679
http://europepmc.org/articles/PMC8023931
http://europepmc.org/articles/PMC8023931
Autor:
Roberta De Godoy, Jayesh Dudhia, Mark E. Morrey, Mustafa S. Rashid, Andrew Carr, Stephanie G. Dakin, Pierre-Alexis Mouthuy, Sarah J. B. Snelling, Roger Smith
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
We investigated endogenous tissue response to a woven and electrospun polydioxanone (PDO) and polycaprolactone (PCL) patch intended for tendon repair. A sheep tendon injury model characterised by a natural history of consistent failure of healing was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4c1698e463e1a80330b56d6da2a339
http://link.springer.com/article/10.1038/s41598-020-61725-5
http://link.springer.com/article/10.1038/s41598-020-61725-5
Autor:
Helen J Knowles, Martin Philpott, Srinivasa R. Rao, Sarah J. B. Snelling, Quitterie C. Larrouture, Adam P. Cribbs
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Osteoclasts are multinucleated, bone-resorbing cells. However, they also digest cartilage during skeletal maintenance, development and in degradative conditions including osteoarthritis, rheumatoid arthritis and primary bone sarcoma. This study explo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca54015a618034d4a9a384cd501e35a
https://ora.ox.ac.uk/objects/uuid:83c153db-a50e-4698-a92b-343317d2b104
https://ora.ox.ac.uk/objects/uuid:83c153db-a50e-4698-a92b-343317d2b104
Autor:
Sarah J. B. Snelling, Andrew Price, Andrew Carr, Edyta Augustyniak, Pierre-Alexis Mouthuy, William Jackson, Adele Kastensson, Roxanna E. Abhari, Luka Savić, Mathew Baldwin
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 129
espite the clinical success of Anterior Cruciate Ligament reconstruction (ACLR) in some patients, unsatisfactory clinical outcomes secondary to graft failure are seen, indicating the need to develop new regeneration strategies. The use of degradable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e4ea3e6867a317348d55e193b62876
https://pubmed.ncbi.nlm.nih.gov/34579923
https://pubmed.ncbi.nlm.nih.gov/34579923